Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19

Detalhes bibliográficos
Autor(a) principal: Lavezzo, Stephanie Zambrano
Data de Publicação: 2022
Outros Autores: Beltrame, Samantha Ellen, Ribeiro, Carolina Heitmann Mares Azevedo, Prete, Ana Cristina Lo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26388
Resumo: Severe cases of COVID-19 may require oxygen support therapies, such as the use of Extracorporeal Oxygenation Membrane (ECMO) and mechanical ventilation (MV). ECMO is a therapy used for temporary support in cases of pulmonary and/or cardiac function failure. This integrative review aimed to assess the scientific literature on the effectiveness of ECMO in critically patients with COVID-19. Articles collected from PubMed, published from December 2019 to June 2021, using the descriptors "COVID-19" and "ECMO" were included in this review. Articles that did not present results on the assessment of the relation between ECMO and COVID-19 and those that fell into the category of letter to the editor model or narrative reviews were excluded. For an integrated discussion, the articles were grouped in a table containing title, objective, method, methodology, results and conclusion. 36 articles were included for the integrative analysis. It was possible to evidence a greater efficacy of ECMO in younger patients (< 71 years), with greater disease severity and in those with comorbidities. However, the therapy has certain types of complications, such as a high risk of thrombosis and circuit failure, which can lead to an unsuccessful weaning from ECMO. ECMO therapy can help critically patients with COVID-19 in certain conditions, although it may increase the risk of thrombosis, and further studies are needed for better clarification.                                                    
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spelling Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19 Eficacia de la terapia de oxigenación por membrana extracorpórea (ECMO) en pacientes críticos con COVID-19 Efetividade da terapia por oxigenação de membrana extracorpórea (ECMO) em pacientes críticos com COVID-19COVID-19Extracorporeal Membrane OxygenationEficácia.COVID-19Oxigenación por Membrana ExtracorpóreaEficacia.COVID-19Oxigenação por Membrana ExtracorpóreaEfficiency.Severe cases of COVID-19 may require oxygen support therapies, such as the use of Extracorporeal Oxygenation Membrane (ECMO) and mechanical ventilation (MV). ECMO is a therapy used for temporary support in cases of pulmonary and/or cardiac function failure. This integrative review aimed to assess the scientific literature on the effectiveness of ECMO in critically patients with COVID-19. Articles collected from PubMed, published from December 2019 to June 2021, using the descriptors "COVID-19" and "ECMO" were included in this review. Articles that did not present results on the assessment of the relation between ECMO and COVID-19 and those that fell into the category of letter to the editor model or narrative reviews were excluded. For an integrated discussion, the articles were grouped in a table containing title, objective, method, methodology, results and conclusion. 36 articles were included for the integrative analysis. It was possible to evidence a greater efficacy of ECMO in younger patients (< 71 years), with greater disease severity and in those with comorbidities. However, the therapy has certain types of complications, such as a high risk of thrombosis and circuit failure, which can lead to an unsuccessful weaning from ECMO. ECMO therapy can help critically patients with COVID-19 in certain conditions, although it may increase the risk of thrombosis, and further studies are needed for better clarification.                                                    Los casos graves de COVID-19 pueden requerir terapias de apoyo de oxígeno, como el uso de oxigenación por membrana extracorpórea (ECMO) y ventilación mecánica (VM). ECMO es una terapia utilizada como soporte temporal en casos de falla de la función pulmonar y/o cardíaca. Esta revisión integradora tuvo como objetivo evaluar la literatura científica sobre la efectividad de ECMO en pacientes críticos con COVID-19. En esta revisión se incluyeron artículos recopilados de PubMed, publicados entre diciembre de 2019 y junio de 2021, utilizando los descriptores "COVID-19" y "ECMO". Se excluyeron los artículos que no presentaron resultados sobre la evaluación de la relación de ECMO con el COVID-19 y aquellos que encajan en la categoría de modelo de carta al editor o reseñas narrativas. Para una discusión integrada, los artículos fueron agrupados en una tabla que contenía título, objetivo, método, metodología, resultados y conclusión. Para el análisis integrador se incluyeron 36 artículos. Se pudo evidenciar una mayor efectividad de ECMO en pacientes más jóvenes (< 71 años), con mayor gravedad de la enfermedad y en aquellos con comorbilidades. Sin embargo, la terapia tiene ciertos tipos de complicaciones, como un alto riesgo de trombosis y fallas en el circuito, que pueden conducir a un destete ECMO fallido. La terapia ECMO puede ayudar a los pacientes críticos con COVID-19 en ciertas condiciones, aunque puede aumentar el riesgo de trombosis, y se necesitan más estudios para obtener más aclaraciones.Casos graves de COVID-19 podem necessitar de terapias de suporte de oxigênio, como a utilização de Membrana de Oxigenação Extracorpórea (ECMO) e ventilação mecânica (VM). A ECMO é uma terapia usada para suporte temporário em casos de falência da função pulmonar e/ou cardíaca. Esta revisão integrativa objetivou avaliar a literatura científica sobre a efetividade da ECMO em pacientes críticos com COVID-19. Foram incluídos na presente revisão artigos coletados do PubMed, publicados no período de dezembro de 2019 a junho de 2021, utilizando-se os descritores “COVID-19” e “ECMO”. Foram excluídos artigos que não apresentavam resultados sobre a avaliação da relação da ECMO com a COVID-19 e os que se enquadravam na categoria de modelo de carta ao editor ou revisões narrativas. Para a discussão de forma integrada, os artigos foram agrupados em uma tabela contendo título, objetivo, método, metodologia, resultados e conclusão. Foram incluídos para a análise integrativa, 36 artigos. Foi possível evidenciar uma maior eficácia da ECMO nos pacientes mais jovens (< 71 anos), com maior gravidade da doença e nos que apresentavam comorbidades. Porém, a terapia apresenta certos tipos de complicações, como alto risco de trombose e falhas no circuito, o que podem levar a um desmame malsucedido da ECMO. A terapia com ECMO pode auxiliar pacientes graves com COVID-19 em determinadas condições, embora possa aumentar o risco de trombose, sendo necessários mais estudos para um melhor esclarecimento.                                                   Research, Society and Development2022-02-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2638810.33448/rsd-v11i3.26388Research, Society and Development; Vol. 11 No. 3; e5911326388Research, Society and Development; Vol. 11 Núm. 3; e5911326388Research, Society and Development; v. 11 n. 3; e59113263882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26388/23001Copyright (c) 2022 Stephanie Zambrano Lavezzo; Samantha Ellen Beltrame; Carolina Heitmann Mares Azevedo Ribeiro; Ana Cristina Lo Pretehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLavezzo, Stephanie Zambrano Beltrame, Samantha Ellen Ribeiro, Carolina Heitmann Mares Azevedo Prete, Ana Cristina Lo 2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26388Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:26.985873Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
Eficacia de la terapia de oxigenación por membrana extracorpórea (ECMO) en pacientes críticos con COVID-19
Efetividade da terapia por oxigenação de membrana extracorpórea (ECMO) em pacientes críticos com COVID-19
title Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
spellingShingle Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
Lavezzo, Stephanie Zambrano
COVID-19
Extracorporeal Membrane Oxygenation
Eficácia.
COVID-19
Oxigenación por Membrana Extracorpórea
Eficacia.
COVID-19
Oxigenação por Membrana Extracorpórea
Efficiency.
title_short Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
title_full Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
title_fullStr Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
title_full_unstemmed Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
title_sort Effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in critically patients with COVID-19
author Lavezzo, Stephanie Zambrano
author_facet Lavezzo, Stephanie Zambrano
Beltrame, Samantha Ellen
Ribeiro, Carolina Heitmann Mares Azevedo
Prete, Ana Cristina Lo
author_role author
author2 Beltrame, Samantha Ellen
Ribeiro, Carolina Heitmann Mares Azevedo
Prete, Ana Cristina Lo
author2_role author
author
author
dc.contributor.author.fl_str_mv Lavezzo, Stephanie Zambrano
Beltrame, Samantha Ellen
Ribeiro, Carolina Heitmann Mares Azevedo
Prete, Ana Cristina Lo
dc.subject.por.fl_str_mv COVID-19
Extracorporeal Membrane Oxygenation
Eficácia.
COVID-19
Oxigenación por Membrana Extracorpórea
Eficacia.
COVID-19
Oxigenação por Membrana Extracorpórea
Efficiency.
topic COVID-19
Extracorporeal Membrane Oxygenation
Eficácia.
COVID-19
Oxigenación por Membrana Extracorpórea
Eficacia.
COVID-19
Oxigenação por Membrana Extracorpórea
Efficiency.
description Severe cases of COVID-19 may require oxygen support therapies, such as the use of Extracorporeal Oxygenation Membrane (ECMO) and mechanical ventilation (MV). ECMO is a therapy used for temporary support in cases of pulmonary and/or cardiac function failure. This integrative review aimed to assess the scientific literature on the effectiveness of ECMO in critically patients with COVID-19. Articles collected from PubMed, published from December 2019 to June 2021, using the descriptors "COVID-19" and "ECMO" were included in this review. Articles that did not present results on the assessment of the relation between ECMO and COVID-19 and those that fell into the category of letter to the editor model or narrative reviews were excluded. For an integrated discussion, the articles were grouped in a table containing title, objective, method, methodology, results and conclusion. 36 articles were included for the integrative analysis. It was possible to evidence a greater efficacy of ECMO in younger patients (< 71 years), with greater disease severity and in those with comorbidities. However, the therapy has certain types of complications, such as a high risk of thrombosis and circuit failure, which can lead to an unsuccessful weaning from ECMO. ECMO therapy can help critically patients with COVID-19 in certain conditions, although it may increase the risk of thrombosis, and further studies are needed for better clarification.                                                    
publishDate 2022
dc.date.none.fl_str_mv 2022-02-12
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dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26388
10.33448/rsd-v11i3.26388
url https://rsdjournal.org/index.php/rsd/article/view/26388
identifier_str_mv 10.33448/rsd-v11i3.26388
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dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 3; e5911326388
Research, Society and Development; Vol. 11 Núm. 3; e5911326388
Research, Society and Development; v. 11 n. 3; e5911326388
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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