The third generation of drug-eluting stents: reassuring data while we wait for the next one

Detalhes bibliográficos
Autor(a) principal: Baptista, Sérgio
Data de Publicação: 2021
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54357
Resumo: © 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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spelling The third generation of drug-eluting stents: reassuring data while we wait for the next oneA terceira geração de endopróteses com efeito de droga: dados tranquilizadores enquanto esperamos pela próxima© 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)The benefits of new technologies almost always come at a cost, often creating new problems, for which new solutions must be sought. The development of coronary stents is a perfect example of this. The first bare-metal stents (BMS) revolutionized percutaneous coronary intervention, since they overcame the acute and late elastic recoil seen after balloon angioplasty, thus significantly reducing the risk of restenosis, and solved the problem of acute vessel closure associated with balloon angioplasty due to vessel dissection. However, despite these benefits, BMS were associated with neointimal hyperplasia due to deep arterial injury, resulting in in-stent restenosis in 15-30% of cases. Stents eluting antiproliferative agents were the next step. The first generation of drug-eluting stents (DES) used sirolimus (Cypher, Cordis J&J) and paclitaxel (Taxus, Boston Scientific), incorporated in biostable polymers coating stainless steel stent platforms.ElsevierRepositório da Universidade de LisboaBaptista, Sérgio2022-09-07T14:05:16Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54357engRev Port Cardiol (Engl Ed). 2021 Feb;40(2):77-800870-255110.1016/j.repc.2020.12.0042174-2030info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:00:06Zoai:repositorio.ul.pt:10451/54357Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:04:51.416197Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The third generation of drug-eluting stents: reassuring data while we wait for the next one
A terceira geração de endopróteses com efeito de droga: dados tranquilizadores enquanto esperamos pela próxima
title The third generation of drug-eluting stents: reassuring data while we wait for the next one
spellingShingle The third generation of drug-eluting stents: reassuring data while we wait for the next one
Baptista, Sérgio
title_short The third generation of drug-eluting stents: reassuring data while we wait for the next one
title_full The third generation of drug-eluting stents: reassuring data while we wait for the next one
title_fullStr The third generation of drug-eluting stents: reassuring data while we wait for the next one
title_full_unstemmed The third generation of drug-eluting stents: reassuring data while we wait for the next one
title_sort The third generation of drug-eluting stents: reassuring data while we wait for the next one
author Baptista, Sérgio
author_facet Baptista, Sérgio
author_role author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Baptista, Sérgio
description © 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2022-09-07T14:05:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54357
url http://hdl.handle.net/10451/54357
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Port Cardiol (Engl Ed). 2021 Feb;40(2):77-80
0870-2551
10.1016/j.repc.2020.12.004
2174-2030
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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