Continuous Glucose Monitoring in Preterm infants- A Systematic Review

• Autor(a) principal: Tiago Jorge Cardoso Pinto Ribeiro
• Data de Publicação: 2021
• Tipo de documento: Dissertação
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://hdl.handle.net/10216/134450
• topic: Medicina clínica; Clinical medicine

Introduction: Dysglycemic events are common occurrences in preterm infants, this imbalance of blood glucose levels could lead to increased risk of death, sepsis, neurosensorial impairment, retinopathy of premature, among other unfavorable consequences. Continuous glucose monitoring (CGM) allows for an early detection of dysglycemic events. This systematic review aims to assess the effect of continuous glucose monitoring in preterm infants. Methods We thoroughly search several electronic databases from August 2020 to February 2021, we included reports based on inclusion/exclusion criteria. Primary outcomes where percentage of time spent in euglycemic range, number of dysglycemic episodes and mortality. Results: Three studies were included after screening, a total of 278 combined preterm newborns were included, with bias risk ranging from low to intermediate. CGM was compared with intermittent methods of blood glucose measurement (capillary test), interventions and outcomes evaluated differed between studies. Conclusions: CGM allows for better glycemic control, reduces number of painful readings, allows for early detection of dysglycemic events and reduces time spent in dysglycemic states (both hyperglycemia and hypoglycemia) when combined with corrective measures. Further research needs to be conducted to evaluate the long-term impact of CGM in neurosensorial and physical development of preterm infants.