Insights into nanomedicine for head and neck cancer diagnosis and treatment

Detalhes bibliográficos
Autor(a) principal: Viegas, Cláudia Sofia
Data de Publicação: 2022
Outros Autores: Pereira, Daniela S. M., Fonte, Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/17743
Resumo: Head and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed.
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spelling Insights into nanomedicine for head and neck cancer diagnosis and treatmentHead and neck cancerNanomedicineDrug deliveryNanocarrierHyperthermiaTarget therapeuticTheragnosticHead and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed.MDPISapientiaViegas, Cláudia SofiaPereira, Daniela S. M.Fonte, Pedro2022-03-31T15:52:41Z2022-03-112022-03-24T14:47:29Z2022-03-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/17743engMaterials 15 (6): 2086 (2022)1996-194410.3390/ma15062086info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-13T02:07:16Zoai:sapientia.ualg.pt:10400.1/17743Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:07:37.056001Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Insights into nanomedicine for head and neck cancer diagnosis and treatment
title Insights into nanomedicine for head and neck cancer diagnosis and treatment
spellingShingle Insights into nanomedicine for head and neck cancer diagnosis and treatment
Viegas, Cláudia Sofia
Head and neck cancer
Nanomedicine
Drug delivery
Nanocarrier
Hyperthermia
Target therapeutic
Theragnostic
title_short Insights into nanomedicine for head and neck cancer diagnosis and treatment
title_full Insights into nanomedicine for head and neck cancer diagnosis and treatment
title_fullStr Insights into nanomedicine for head and neck cancer diagnosis and treatment
title_full_unstemmed Insights into nanomedicine for head and neck cancer diagnosis and treatment
title_sort Insights into nanomedicine for head and neck cancer diagnosis and treatment
author Viegas, Cláudia Sofia
author_facet Viegas, Cláudia Sofia
Pereira, Daniela S. M.
Fonte, Pedro
author_role author
author2 Pereira, Daniela S. M.
Fonte, Pedro
author2_role author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Viegas, Cláudia Sofia
Pereira, Daniela S. M.
Fonte, Pedro
dc.subject.por.fl_str_mv Head and neck cancer
Nanomedicine
Drug delivery
Nanocarrier
Hyperthermia
Target therapeutic
Theragnostic
topic Head and neck cancer
Nanomedicine
Drug delivery
Nanocarrier
Hyperthermia
Target therapeutic
Theragnostic
description Head and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-31T15:52:41Z
2022-03-11
2022-03-24T14:47:29Z
2022-03-11T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/17743
url http://hdl.handle.net/10400.1/17743
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials 15 (6): 2086 (2022)
1996-1944
10.3390/ma15062086
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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