Insights into nanomedicine for head and neck cancer diagnosis and treatment
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/17743 |
Resumo: | Head and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed. |
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Insights into nanomedicine for head and neck cancer diagnosis and treatmentHead and neck cancerNanomedicineDrug deliveryNanocarrierHyperthermiaTarget therapeuticTheragnosticHead and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed.MDPISapientiaViegas, Cláudia SofiaPereira, Daniela S. M.Fonte, Pedro2022-03-31T15:52:41Z2022-03-112022-03-24T14:47:29Z2022-03-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/17743engMaterials 15 (6): 2086 (2022)1996-194410.3390/ma15062086info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-13T02:07:16Zoai:sapientia.ualg.pt:10400.1/17743Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:07:37.056001Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
title |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
spellingShingle |
Insights into nanomedicine for head and neck cancer diagnosis and treatment Viegas, Cláudia Sofia Head and neck cancer Nanomedicine Drug delivery Nanocarrier Hyperthermia Target therapeutic Theragnostic |
title_short |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
title_full |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
title_fullStr |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
title_full_unstemmed |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
title_sort |
Insights into nanomedicine for head and neck cancer diagnosis and treatment |
author |
Viegas, Cláudia Sofia |
author_facet |
Viegas, Cláudia Sofia Pereira, Daniela S. M. Fonte, Pedro |
author_role |
author |
author2 |
Pereira, Daniela S. M. Fonte, Pedro |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Viegas, Cláudia Sofia Pereira, Daniela S. M. Fonte, Pedro |
dc.subject.por.fl_str_mv |
Head and neck cancer Nanomedicine Drug delivery Nanocarrier Hyperthermia Target therapeutic Theragnostic |
topic |
Head and neck cancer Nanomedicine Drug delivery Nanocarrier Hyperthermia Target therapeutic Theragnostic |
description |
Head and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-31T15:52:41Z 2022-03-11 2022-03-24T14:47:29Z 2022-03-11T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/17743 |
url |
http://hdl.handle.net/10400.1/17743 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials 15 (6): 2086 (2022) 1996-1944 10.3390/ma15062086 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133321640280064 |