Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations

Detalhes bibliográficos
Autor(a) principal: Klemm, A.
Data de Publicação: 2019
Outros Autores: Gomez-Florit, Manuel, Carvalho, P. A., Wachendörfer, M., Gomes, Manuela E., Haugen, H. J., Tiainen, H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/58602
Resumo: A pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation.
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spelling Grain boundary corrosion in TiO2 bone scaffolds doped with group II cationsCorrosionDoped TiO2Grain boundaryOsteogenic differentiationSrTiO3Engenharia e Tecnologia::Biotecnologia IndustrialScience & TechnologyA pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation.(undefined)info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoKlemm, A.Gomez-Florit, ManuelCarvalho, P. A.Wachendörfer, M.Gomes, Manuela E.Haugen, H. J.Tiainen, H.2019-042019-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/58602engKlemm A., Gómez-Florit M., Carvalho P. A., Wachendörfer M., Gomes M. E., Haugen H. J., Tiainen H. Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations, Journal Of The European Ceramic Society, Vol. 39, Issue 4, pp. 1577-1585, doi:10.1016/j.jeurceramsoc.2018.12.055, 20180955-221910.1016/j.jeurceramsoc.2018.12.055https://www.sciencedirect.com/science/article/pii/S095522191830774Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:18:31Zoai:repositorium.sdum.uminho.pt:1822/58602Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:11:21.278631Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
title Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
spellingShingle Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
Klemm, A.
Corrosion
Doped TiO2
Grain boundary
Osteogenic differentiation
SrTiO3
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
title_short Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
title_full Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
title_fullStr Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
title_full_unstemmed Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
title_sort Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
author Klemm, A.
author_facet Klemm, A.
Gomez-Florit, Manuel
Carvalho, P. A.
Wachendörfer, M.
Gomes, Manuela E.
Haugen, H. J.
Tiainen, H.
author_role author
author2 Gomez-Florit, Manuel
Carvalho, P. A.
Wachendörfer, M.
Gomes, Manuela E.
Haugen, H. J.
Tiainen, H.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Klemm, A.
Gomez-Florit, Manuel
Carvalho, P. A.
Wachendörfer, M.
Gomes, Manuela E.
Haugen, H. J.
Tiainen, H.
dc.subject.por.fl_str_mv Corrosion
Doped TiO2
Grain boundary
Osteogenic differentiation
SrTiO3
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
topic Corrosion
Doped TiO2
Grain boundary
Osteogenic differentiation
SrTiO3
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
description A pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation.
publishDate 2019
dc.date.none.fl_str_mv 2019-04
2019-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/58602
url http://hdl.handle.net/1822/58602
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Klemm A., Gómez-Florit M., Carvalho P. A., Wachendörfer M., Gomes M. E., Haugen H. J., Tiainen H. Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations, Journal Of The European Ceramic Society, Vol. 39, Issue 4, pp. 1577-1585, doi:10.1016/j.jeurceramsoc.2018.12.055, 2018
0955-2219
10.1016/j.jeurceramsoc.2018.12.055
https://www.sciencedirect.com/science/article/pii/S095522191830774X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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