Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/58602 |
Resumo: | A pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation. |
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Grain boundary corrosion in TiO2 bone scaffolds doped with group II cationsCorrosionDoped TiO2Grain boundaryOsteogenic differentiationSrTiO3Engenharia e Tecnologia::Biotecnologia IndustrialScience & TechnologyA pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation.(undefined)info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoKlemm, A.Gomez-Florit, ManuelCarvalho, P. A.Wachendörfer, M.Gomes, Manuela E.Haugen, H. J.Tiainen, H.2019-042019-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/58602engKlemm A., Gómez-Florit M., Carvalho P. A., Wachendörfer M., Gomes M. E., Haugen H. J., Tiainen H. Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations, Journal Of The European Ceramic Society, Vol. 39, Issue 4, pp. 1577-1585, doi:10.1016/j.jeurceramsoc.2018.12.055, 20180955-221910.1016/j.jeurceramsoc.2018.12.055https://www.sciencedirect.com/science/article/pii/S095522191830774Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:18:31Zoai:repositorium.sdum.uminho.pt:1822/58602Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:11:21.278631Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
title |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
spellingShingle |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations Klemm, A. Corrosion Doped TiO2 Grain boundary Osteogenic differentiation SrTiO3 Engenharia e Tecnologia::Biotecnologia Industrial Science & Technology |
title_short |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
title_full |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
title_fullStr |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
title_full_unstemmed |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
title_sort |
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations |
author |
Klemm, A. |
author_facet |
Klemm, A. Gomez-Florit, Manuel Carvalho, P. A. Wachendörfer, M. Gomes, Manuela E. Haugen, H. J. Tiainen, H. |
author_role |
author |
author2 |
Gomez-Florit, Manuel Carvalho, P. A. Wachendörfer, M. Gomes, Manuela E. Haugen, H. J. Tiainen, H. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Klemm, A. Gomez-Florit, Manuel Carvalho, P. A. Wachendörfer, M. Gomes, Manuela E. Haugen, H. J. Tiainen, H. |
dc.subject.por.fl_str_mv |
Corrosion Doped TiO2 Grain boundary Osteogenic differentiation SrTiO3 Engenharia e Tecnologia::Biotecnologia Industrial Science & Technology |
topic |
Corrosion Doped TiO2 Grain boundary Osteogenic differentiation SrTiO3 Engenharia e Tecnologia::Biotecnologia Industrial Science & Technology |
description |
A pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. Cationic doping of TiO2 showed to increase the compressive strength but increased the amount of impurities in grain boundaries as well. Therefore, this study showed the different grain boundary formation for Ca, Sr and Mg doped scaffolds and their corrosion behavior. After corrosion, the amorphous phase in grain boundaries was dissolved in all doped scaffolds. Differences occurred due to the formation of an additional crystalline phase in Sr doped scaffolds. The presence of an amorphous and crystalline phase led to an inhomogeneous dissolution in grain boundaries and a significant decrease in compressive strength already after 4 h in contact with an acidic environment. Released ions did not show any cytotoxic effect on hASCs. Mg doped TiO2 scaffolds led to sig- nificant increased osteogenic differentiation. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-04 2019-04-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/58602 |
url |
http://hdl.handle.net/1822/58602 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Klemm A., Gómez-Florit M., Carvalho P. A., Wachendörfer M., Gomes M. E., Haugen H. J., Tiainen H. Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations, Journal Of The European Ceramic Society, Vol. 39, Issue 4, pp. 1577-1585, doi:10.1016/j.jeurceramsoc.2018.12.055, 2018 0955-2219 10.1016/j.jeurceramsoc.2018.12.055 https://www.sciencedirect.com/science/article/pii/S095522191830774X |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132545089011712 |