High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles

Detalhes bibliográficos
Autor(a) principal: Pereira, Joana Isabel Carvalho
Data de Publicação: 2018
Outros Autores: Oliveira, Manoel M. Evangelista, Barbosa, Augusto Alexandre Costa, Vaz, C., Velegraki, A., Zancopé-Oliveira, R. M., Pais, Célia, Sampaio, Paula
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/72685
Resumo: Previous studies have correlated the severity of recurrent vulvovaginal Candida infections (VVC) and balanitis in patients from China with the presence of some dominant genotypes at the ORF RLM1. Here we tested VVC vs non-VVC isolates from Portugal, Brazil and Greece and, although the same genotypes were identified in VVC isolates, they were present in only five out of 150 strains. However, this analysis showed that VVC isolates presented a higher percentage of genotypes with similar high molecular weight alleles, in comparison with strains isolated from other biological sources
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spelling High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight allelesCandida albicansRLM1Vulvovaginal candidiasisAllelesStress resistanceCiências Médicas::Biotecnologia MédicaScience & TechnologyPrevious studies have correlated the severity of recurrent vulvovaginal Candida infections (VVC) and balanitis in patients from China with the presence of some dominant genotypes at the ORF RLM1. Here we tested VVC vs non-VVC isolates from Portugal, Brazil and Greece and, although the same genotypes were identified in VVC isolates, they were present in only five out of 150 strains. However, this analysis showed that VVC isolates presented a higher percentage of genotypes with similar high molecular weight alleles, in comparison with strains isolated from other biological sourcesOxford University PressUniversidade do MinhoPereira, Joana Isabel CarvalhoOliveira, Manoel M. EvangelistaBarbosa, Augusto Alexandre CostaVaz, C.Velegraki, A.Zancopé-Oliveira, R. M.Pais, CéliaSampaio, Paula20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/72685engCarvalho-Pereira, J., Oliveira, M. M. E., Costa-Barbosa, A., Vaz, C., Velegraki, A., Zancopé-Oliveira, R. M., ... & Sampaio, P. (2018). High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles. Medical mycology, 56(5), 649-6511369-37861460-270910.1093/mmy/myx07929420774https://academic.oup.com/mmy/article/56/5/649/4372446info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:29:57Zoai:repositorium.sdum.uminho.pt:1822/72685Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:25:03.092115Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
title High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
spellingShingle High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
Pereira, Joana Isabel Carvalho
Candida albicans
RLM1
Vulvovaginal candidiasis
Alleles
Stress resistance
Ciências Médicas::Biotecnologia Médica
Science & Technology
title_short High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
title_full High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
title_fullStr High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
title_full_unstemmed High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
title_sort High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles
author Pereira, Joana Isabel Carvalho
author_facet Pereira, Joana Isabel Carvalho
Oliveira, Manoel M. Evangelista
Barbosa, Augusto Alexandre Costa
Vaz, C.
Velegraki, A.
Zancopé-Oliveira, R. M.
Pais, Célia
Sampaio, Paula
author_role author
author2 Oliveira, Manoel M. Evangelista
Barbosa, Augusto Alexandre Costa
Vaz, C.
Velegraki, A.
Zancopé-Oliveira, R. M.
Pais, Célia
Sampaio, Paula
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Pereira, Joana Isabel Carvalho
Oliveira, Manoel M. Evangelista
Barbosa, Augusto Alexandre Costa
Vaz, C.
Velegraki, A.
Zancopé-Oliveira, R. M.
Pais, Célia
Sampaio, Paula
dc.subject.por.fl_str_mv Candida albicans
RLM1
Vulvovaginal candidiasis
Alleles
Stress resistance
Ciências Médicas::Biotecnologia Médica
Science & Technology
topic Candida albicans
RLM1
Vulvovaginal candidiasis
Alleles
Stress resistance
Ciências Médicas::Biotecnologia Médica
Science & Technology
description Previous studies have correlated the severity of recurrent vulvovaginal Candida infections (VVC) and balanitis in patients from China with the presence of some dominant genotypes at the ORF RLM1. Here we tested VVC vs non-VVC isolates from Portugal, Brazil and Greece and, although the same genotypes were identified in VVC isolates, they were present in only five out of 150 strains. However, this analysis showed that VVC isolates presented a higher percentage of genotypes with similar high molecular weight alleles, in comparison with strains isolated from other biological sources
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/72685
url http://hdl.handle.net/1822/72685
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Carvalho-Pereira, J., Oliveira, M. M. E., Costa-Barbosa, A., Vaz, C., Velegraki, A., Zancopé-Oliveira, R. M., ... & Sampaio, P. (2018). High variability within Candida albicans transcription factor RLM1: Isolates from vulvovaginal infections show a clear bias toward high molecular weight alleles. Medical mycology, 56(5), 649-651
1369-3786
1460-2709
10.1093/mmy/myx079
29420774
https://academic.oup.com/mmy/article/56/5/649/4372446
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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