Oral tolerance induction protocol to egg white - A report of three pediatric cases

• Autor(a) principal: Granado,Maria Cristina
• Data de Publicação: 2022
• Outros Autores: Sousa,Dinis, Mendes,Ana Raquel, Santalha,Marta, Silva,Armandina, Costa,Alberto
• Tipo de documento: Relatório
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0871-97212022000300229
• topic: Egg hypersensitivity; food hypersensitivity; immunotherapy; oral tolerance induction

ABSTRACT Food allergies are the main cause of anaphylaxis in children. Cow’s milk and egg white are the most common agents and elimination diets are considered the current strategy for their management. Many children can tolerate increasing amounts of the known allergen, and thus, oral tolerance induction protocols seem to be a promising approach. The authors present a protocol drawn up in a pediatric allergic diseases’ outpatient clinic, at a level II hospital, with the aim of egg white oral tolerance induction. During the protocol there is an increase in the amount of egg white offered to children, at the end, tolerance is tested with the ingestion of an entire egg. The protocol was performed in three children with anaphylaxis to egg white. Two children completed the protocol successfully. Oral tolerance to egg white allows a less restrictive diet and improves the quality of life of the patients and their caregivers.