Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis

Detalhes bibliográficos
Autor(a) principal: Cardoso, Ana
Data de Publicação: 2021
Outros Autores: Branco, Carolina, Sant’Ana, Mariana, Costa, Cláudia, Marques Da Silva, Bernardo, Agapito Fonseca, José, Outerelo, Cristina, Gameiro, Joana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/59788
Resumo: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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spelling Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysisChronic haemodialysisHeart failureHypoalbuminaemiaMalnutritionMortality© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Introduction: The prevalence of chronic kidney disease (CKD) and heart failure (HF) has been rising over the past decade, with a prevalence close to 40%. Cardiovascular disease and malnutrition are common comorbidities and known risk factors for mortality in haemodialysis (HD) patients. We aimed to evaluate the one-year mortality rate after dialysis induction, and the impact of serum albumin levels on survival outcomes, in patients with CKD and HF. Methods: This was a retrospective analysis of patients with CKD and HF who underwent chronic HD between January 2016 and December 2019 in a tertiary-care Portuguese hospital. Variables were submitted to univariate and multivariate analysis to determine factors predictive of one-mortality after HD start. Results: In total, 204 patients were analysed (mean age 75.1 ± 10.3 years). Within the first year of HD start, 28.7% of patients died. These patients were significantly older [79.8 ± 7.2 versus 72.9 ± 10.9 years, p < 0.001; OR 1.08 (1.04-1.13), p < 0.001] and had a higher mean Charlson Index [9.0 ± 1.8 versus 8.3 ± 2.0, p = 0.015; OR 1.22 (1.04-1.44), p = 0.017], lower serum creatinine [5.1 ± 1.6 mg/dL versus 5.8 ± 2.0 mg/dL; p = 0.021; OR 0.80 (0.65-0.97), p = 0.022], lower albumin levels [3.1 ± 0.6 g/dL versus 3.4 ± 0.6 g/dL, p < 0.001; OR 0.38 (0.22-0.66), p = 0.001] and started haemodialysis with a central venous catheter more frequently [80.4% versus 66.2%, p = 0.050]. Multivariate analysis identified older age [aOR 1.07 (1.03-1.12), p = 0.002], lower serum creatinine [aOR 0.80 (0.64-0.99), p = 0.049] and lower serum albumin [aOR 0.41 (0.22-0.75), p = 0.004] as predictors of one-year mortality. Conclusion: In our cohort, older age, lower serum creatinine and lower serum albumin were independent risk factors for one-year mortality, highlighting the prognostic importance of malnutrition in patients starting chronic HD.MDPIRepositório da Universidade de LisboaCardoso, AnaBranco, CarolinaSant’Ana, MarianaCosta, CláudiaMarques Da Silva, BernardoAgapito Fonseca, JoséOuterelo, CristinaGameiro, Joana2023-10-16T14:07:47Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/59788engJ Clin Med. 2021 Sep 29;10(19):4518.10.3390/jcm101945182077-0383info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:08:48Zoai:repositorio.ul.pt:10451/59788Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:09:30.280621Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
title Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
spellingShingle Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
Cardoso, Ana
Chronic haemodialysis
Heart failure
Hypoalbuminaemia
Malnutrition
Mortality
title_short Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
title_full Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
title_fullStr Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
title_full_unstemmed Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
title_sort Hypoalbuminaemia and one-year mortality in haemodialysis patients with heart failure: a cohort analysis
author Cardoso, Ana
author_facet Cardoso, Ana
Branco, Carolina
Sant’Ana, Mariana
Costa, Cláudia
Marques Da Silva, Bernardo
Agapito Fonseca, José
Outerelo, Cristina
Gameiro, Joana
author_role author
author2 Branco, Carolina
Sant’Ana, Mariana
Costa, Cláudia
Marques Da Silva, Bernardo
Agapito Fonseca, José
Outerelo, Cristina
Gameiro, Joana
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Cardoso, Ana
Branco, Carolina
Sant’Ana, Mariana
Costa, Cláudia
Marques Da Silva, Bernardo
Agapito Fonseca, José
Outerelo, Cristina
Gameiro, Joana
dc.subject.por.fl_str_mv Chronic haemodialysis
Heart failure
Hypoalbuminaemia
Malnutrition
Mortality
topic Chronic haemodialysis
Heart failure
Hypoalbuminaemia
Malnutrition
Mortality
description © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2023-10-16T14:07:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/59788
url http://hdl.handle.net/10451/59788
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Clin Med. 2021 Sep 29;10(19):4518.
10.3390/jcm10194518
2077-0383
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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