IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies

Detalhes bibliográficos
Autor(a) principal: Alves, Cátia
Data de Publicação: 2018
Outros Autores: Sousa, Ana Rita Lima, Diogo, Duarte Miguel de Melo, Correia, Ilídio Joaquim Sobreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/4708
Resumo: IR780, a molecule with a strong optical absorption and emission in the near infrared (NIR) region, is receiving an increasing attention from researchers working in the area of cancer treatment and imaging. Upon irradiation with NIR light, IR780 can produce reactive oxygen species as well as increase the body temperature, thus being a promising agent for application in cancer photodynamic and photothermal therapy. However, IR780’s poor water solubility, fast clearance, acute toxicity and low tumor uptake may limit its use. To overcome such issues, several types of nanomaterials have been used to encapsulate and deliver IR780 to tumor cells. This mini-review is focused on the application of IR780 based nanostructures for cancer imaging, and photothermal, photodynamic and combinatorial therapies.
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spelling IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapiesCancerCombinatorial therapyImagingR780Photodynamic therapyPhotothermal therapyIR780, a molecule with a strong optical absorption and emission in the near infrared (NIR) region, is receiving an increasing attention from researchers working in the area of cancer treatment and imaging. Upon irradiation with NIR light, IR780 can produce reactive oxygen species as well as increase the body temperature, thus being a promising agent for application in cancer photodynamic and photothermal therapy. However, IR780’s poor water solubility, fast clearance, acute toxicity and low tumor uptake may limit its use. To overcome such issues, several types of nanomaterials have been used to encapsulate and deliver IR780 to tumor cells. This mini-review is focused on the application of IR780 based nanostructures for cancer imaging, and photothermal, photodynamic and combinatorial therapies.ElsevieruBibliorumAlves, CátiaSousa, Ana Rita LimaDiogo, Duarte Miguel de MeloCorreia, Ilídio Joaquim Sobreira2018-03-22T10:26:58Z2018-03-132018-03-13T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/4708engAlves, C.G., Lima-Sousa, R., de Melo-Diogo, D., Louro, R.O., Correia I.J. (2018) “IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies” International Journal of Pharmaceutics, Vol. 542, pp.164-17510.1016/j.ijpharm.2018.03.020metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-20T02:30:33Zoai:ubibliorum.ubi.pt:10400.6/4708Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:45:45.520535Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
title IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
spellingShingle IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
Alves, Cátia
Cancer
Combinatorial therapy
Imaging
R780
Photodynamic therapy
Photothermal therapy
title_short IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
title_full IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
title_fullStr IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
title_full_unstemmed IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
title_sort IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies
author Alves, Cátia
author_facet Alves, Cátia
Sousa, Ana Rita Lima
Diogo, Duarte Miguel de Melo
Correia, Ilídio Joaquim Sobreira
author_role author
author2 Sousa, Ana Rita Lima
Diogo, Duarte Miguel de Melo
Correia, Ilídio Joaquim Sobreira
author2_role author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Alves, Cátia
Sousa, Ana Rita Lima
Diogo, Duarte Miguel de Melo
Correia, Ilídio Joaquim Sobreira
dc.subject.por.fl_str_mv Cancer
Combinatorial therapy
Imaging
R780
Photodynamic therapy
Photothermal therapy
topic Cancer
Combinatorial therapy
Imaging
R780
Photodynamic therapy
Photothermal therapy
description IR780, a molecule with a strong optical absorption and emission in the near infrared (NIR) region, is receiving an increasing attention from researchers working in the area of cancer treatment and imaging. Upon irradiation with NIR light, IR780 can produce reactive oxygen species as well as increase the body temperature, thus being a promising agent for application in cancer photodynamic and photothermal therapy. However, IR780’s poor water solubility, fast clearance, acute toxicity and low tumor uptake may limit its use. To overcome such issues, several types of nanomaterials have been used to encapsulate and deliver IR780 to tumor cells. This mini-review is focused on the application of IR780 based nanostructures for cancer imaging, and photothermal, photodynamic and combinatorial therapies.
publishDate 2018
dc.date.none.fl_str_mv 2018-03-22T10:26:58Z
2018-03-13
2018-03-13T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/4708
url http://hdl.handle.net/10400.6/4708
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Alves, C.G., Lima-Sousa, R., de Melo-Diogo, D., Louro, R.O., Correia I.J. (2018) “IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies” International Journal of Pharmaceutics, Vol. 542, pp.164-175
10.1016/j.ijpharm.2018.03.020
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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