Significance of Cancer Stem Cells in Anti-Cancer Therapies

Detalhes bibliográficos
Autor(a) principal: Botelho, Mónica
Data de Publicação: 2016
Outros Autores: Alves, Helena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/4534
Resumo: Stem cells are the focus of cutting edge research interest because of their competence both to self-renew and proliferate, and to differentiate into a variety of tissues, offering enticing prospects of growing replacement organs in vitro, among other possible therapeutic implications. It is conceivable that cancer stem cells share a number of biological hallmarks that are different from their normal-tissue counterparts and that these might be taken advantage of for therapeutic benefits. In this review we discuss the significance of cancer stem cells in diagnosis and prognosis of cancer as well as in the development of new strategies for anti-cancer drug design.
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spelling Significance of Cancer Stem Cells in Anti-Cancer TherapiesStem CellsCancerStem Cell MarkersAnti-cancer TherapiesStem cells are the focus of cutting edge research interest because of their competence both to self-renew and proliferate, and to differentiate into a variety of tissues, offering enticing prospects of growing replacement organs in vitro, among other possible therapeutic implications. It is conceivable that cancer stem cells share a number of biological hallmarks that are different from their normal-tissue counterparts and that these might be taken advantage of for therapeutic benefits. In this review we discuss the significance of cancer stem cells in diagnosis and prognosis of cancer as well as in the development of new strategies for anti-cancer drug design.Hyderabad : PeertechzRepositório Científico do Instituto Nacional de SaúdeBotelho, MónicaAlves, Helena2017-03-07T13:24:29Z2016-12-312016-12-31T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/4534engInt J Immunother Cancer Res. 2016;2(1):14-16. Epub 2016 Dec 312455-8591info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:40:23Zoai:repositorio.insa.pt:10400.18/4534Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:39:18.853708Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Significance of Cancer Stem Cells in Anti-Cancer Therapies
title Significance of Cancer Stem Cells in Anti-Cancer Therapies
spellingShingle Significance of Cancer Stem Cells in Anti-Cancer Therapies
Botelho, Mónica
Stem Cells
Cancer
Stem Cell Markers
Anti-cancer Therapies
title_short Significance of Cancer Stem Cells in Anti-Cancer Therapies
title_full Significance of Cancer Stem Cells in Anti-Cancer Therapies
title_fullStr Significance of Cancer Stem Cells in Anti-Cancer Therapies
title_full_unstemmed Significance of Cancer Stem Cells in Anti-Cancer Therapies
title_sort Significance of Cancer Stem Cells in Anti-Cancer Therapies
author Botelho, Mónica
author_facet Botelho, Mónica
Alves, Helena
author_role author
author2 Alves, Helena
author2_role author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Botelho, Mónica
Alves, Helena
dc.subject.por.fl_str_mv Stem Cells
Cancer
Stem Cell Markers
Anti-cancer Therapies
topic Stem Cells
Cancer
Stem Cell Markers
Anti-cancer Therapies
description Stem cells are the focus of cutting edge research interest because of their competence both to self-renew and proliferate, and to differentiate into a variety of tissues, offering enticing prospects of growing replacement organs in vitro, among other possible therapeutic implications. It is conceivable that cancer stem cells share a number of biological hallmarks that are different from their normal-tissue counterparts and that these might be taken advantage of for therapeutic benefits. In this review we discuss the significance of cancer stem cells in diagnosis and prognosis of cancer as well as in the development of new strategies for anti-cancer drug design.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-31
2016-12-31T00:00:00Z
2017-03-07T13:24:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/4534
url http://hdl.handle.net/10400.18/4534
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Immunother Cancer Res. 2016;2(1):14-16. Epub 2016 Dec 31
2455-8591
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hyderabad : Peertechz
publisher.none.fl_str_mv Hyderabad : Peertechz
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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