Rethinking Alzheimer’s disease

Detalhes bibliográficos
Autor(a) principal: De Mendonça, Alexandre
Data de Publicação: 2012
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/49159
Resumo: Copyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
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spelling Rethinking Alzheimer’s diseaseCopyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.Alzheimer’s disease (AD) is a neurodegenerative disorder with insidious onset and progressive course, which prevalence increases with the age. It is characterized by neuronal degeneration and death, related to the deposition in the brain of the amyloid β1–42 peptide and the hyperphosphorylated tau protein, and initially affects brain areas, namely the hippocampus and other medial temporal lobe structures, which are important for memory processes (Blennow et al., 2006). As a consequence of the aging of the population, the number of patients with AD and other dementias, as well as the number of elderly people who, although not demented, suffer from significant cognitive decline, is growing worrisomely (Alzheimer’s Disease International, 2009).FrontiersRepositório da Universidade de LisboaDe Mendonça, Alexandre2021-07-27T13:13:37Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49159engFront Neurol. 2012 Mar 27;3:4510.3389/fneur.2012.000451664-2295info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:52:34Zoai:repositorio.ul.pt:10451/49159Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:43.605672Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rethinking Alzheimer’s disease
title Rethinking Alzheimer’s disease
spellingShingle Rethinking Alzheimer’s disease
De Mendonça, Alexandre
title_short Rethinking Alzheimer’s disease
title_full Rethinking Alzheimer’s disease
title_fullStr Rethinking Alzheimer’s disease
title_full_unstemmed Rethinking Alzheimer’s disease
title_sort Rethinking Alzheimer’s disease
author De Mendonça, Alexandre
author_facet De Mendonça, Alexandre
author_role author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv De Mendonça, Alexandre
description Copyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
2021-07-27T13:13:37Z
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dc.relation.none.fl_str_mv Front Neurol. 2012 Mar 27;3:45
10.3389/fneur.2012.00045
1664-2295
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