Rethinking Alzheimer’s disease
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/49159 |
Resumo: | Copyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
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Rethinking Alzheimer’s diseaseCopyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.Alzheimer’s disease (AD) is a neurodegenerative disorder with insidious onset and progressive course, which prevalence increases with the age. It is characterized by neuronal degeneration and death, related to the deposition in the brain of the amyloid β1–42 peptide and the hyperphosphorylated tau protein, and initially affects brain areas, namely the hippocampus and other medial temporal lobe structures, which are important for memory processes (Blennow et al., 2006). As a consequence of the aging of the population, the number of patients with AD and other dementias, as well as the number of elderly people who, although not demented, suffer from significant cognitive decline, is growing worrisomely (Alzheimer’s Disease International, 2009).FrontiersRepositório da Universidade de LisboaDe Mendonça, Alexandre2021-07-27T13:13:37Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49159engFront Neurol. 2012 Mar 27;3:4510.3389/fneur.2012.000451664-2295info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:52:34Zoai:repositorio.ul.pt:10451/49159Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:43.605672Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Rethinking Alzheimer’s disease |
title |
Rethinking Alzheimer’s disease |
spellingShingle |
Rethinking Alzheimer’s disease De Mendonça, Alexandre |
title_short |
Rethinking Alzheimer’s disease |
title_full |
Rethinking Alzheimer’s disease |
title_fullStr |
Rethinking Alzheimer’s disease |
title_full_unstemmed |
Rethinking Alzheimer’s disease |
title_sort |
Rethinking Alzheimer’s disease |
author |
De Mendonça, Alexandre |
author_facet |
De Mendonça, Alexandre |
author_role |
author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
De Mendonça, Alexandre |
description |
Copyright: © 2012 de Mendonça. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 2012-01-01T00:00:00Z 2021-07-27T13:13:37Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/49159 |
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http://hdl.handle.net/10451/49159 |
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eng |
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eng |
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Front Neurol. 2012 Mar 27;3:45 10.3389/fneur.2012.00045 1664-2295 |
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openAccess |
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Frontiers |
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Frontiers |
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