Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient

Detalhes bibliográficos
Autor(a) principal: Ventura Aguiar, P.
Data de Publicação: 2015
Outros Autores: Dias, C., Azevedo, P., Silva, H., Almeida, M., Pedroso, S., Martins, L., Dias, L., Rodrigues, A., Viscaíño, R., Cabrita, A., Henriques, A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.16/1988
Resumo: BACKGROUND: Histiocytic sarcoma (HS) is a rare hematologic neoplasm with a few hundred cases having been described to date.
id RCAP_700fff47dd6d1322340f77c721c5f6ec
oai_identifier_str oai:repositorio.chporto.pt:10400.16/1988
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipientChronic kidney diseaseHistiocytic sarcomaMalignancyPost-transplant lymphoproliferative diseaseTransplantBACKGROUND: Histiocytic sarcoma (HS) is a rare hematologic neoplasm with a few hundred cases having been described to date.CASE PRESENTATION: We report the case of a 56-year-old woman with a history of hepatitis C infection and chronic kidney disease (CKD), submitted to a kidney transplant in 1984, under maintenance immunosuppression with prednisone and azathioprine. Patient presented with a relentlessly growing mass on her right front thorax. It was painless, smooth, and adherent to the deep muscle. Laboratory studies were unremarkable. Ultrasonography and computerized tomography (CT) scan revealed a highly vascularized heterogeneous mass (8×9 cm), with a necrotic centre. Positron emission tomography (PET) scan demonstrated multiple thoracic, abdominal, and pelvic nodules. Histology revealed a highly undifferentiated HS (vimentin, CD68, CD99, and CD4 positive). In spite of having started treatment with etoposide and thalidomide, no clinical response was achieved and the patient died three months later.CONCLUSIONS: To the authors' knowledge, this is the first described case of HS in a solid organ transplant patient.Society of Diabetic Nephropathy PreventionRepositório Científico do Centro Hospitalar Universitário de Santo AntónioVentura Aguiar, P.Dias, C.Azevedo, P.Silva, H.Almeida, M.Pedroso, S.Martins, L.Dias, L.Rodrigues, A.Viscaíño, R.Cabrita, A.Henriques, A.2016-08-01T10:54:33Z2015-072015-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/1988engJ Nephropathol. 2015 Jul;4(3):97-100.2251-836310.12860/jnp.2015.18info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T10:58:35Zoai:repositorio.chporto.pt:10400.16/1988Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:17.556511Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
title Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
spellingShingle Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
Ventura Aguiar, P.
Chronic kidney disease
Histiocytic sarcoma
Malignancy
Post-transplant lymphoproliferative disease
Transplant
title_short Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
title_full Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
title_fullStr Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
title_full_unstemmed Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
title_sort Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient
author Ventura Aguiar, P.
author_facet Ventura Aguiar, P.
Dias, C.
Azevedo, P.
Silva, H.
Almeida, M.
Pedroso, S.
Martins, L.
Dias, L.
Rodrigues, A.
Viscaíño, R.
Cabrita, A.
Henriques, A.
author_role author
author2 Dias, C.
Azevedo, P.
Silva, H.
Almeida, M.
Pedroso, S.
Martins, L.
Dias, L.
Rodrigues, A.
Viscaíño, R.
Cabrita, A.
Henriques, A.
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Centro Hospitalar Universitário de Santo António
dc.contributor.author.fl_str_mv Ventura Aguiar, P.
Dias, C.
Azevedo, P.
Silva, H.
Almeida, M.
Pedroso, S.
Martins, L.
Dias, L.
Rodrigues, A.
Viscaíño, R.
Cabrita, A.
Henriques, A.
dc.subject.por.fl_str_mv Chronic kidney disease
Histiocytic sarcoma
Malignancy
Post-transplant lymphoproliferative disease
Transplant
topic Chronic kidney disease
Histiocytic sarcoma
Malignancy
Post-transplant lymphoproliferative disease
Transplant
description BACKGROUND: Histiocytic sarcoma (HS) is a rare hematologic neoplasm with a few hundred cases having been described to date.
publishDate 2015
dc.date.none.fl_str_mv 2015-07
2015-07-01T00:00:00Z
2016-08-01T10:54:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.16/1988
url http://hdl.handle.net/10400.16/1988
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Nephropathol. 2015 Jul;4(3):97-100.
2251-8363
10.12860/jnp.2015.18
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Society of Diabetic Nephropathy Prevention
publisher.none.fl_str_mv Society of Diabetic Nephropathy Prevention
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799133644163383296

Registros relacionados