Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report

Detalhes bibliográficos
Autor(a) principal: Liz-Pimenta, Joana
Data de Publicação: 2022
Outros Autores: Dias, Nuno, Barbosa, Miguel, Sousa, Marta
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350
Resumo: Priapism may be a side effect of low-molecular-weight heparins, and its mechanism remains unknown. The authors present a clinical case of a 51-year-old male patient with oligodendroglioma. The patient presented ischemic priapism on the third month after starting tinzaparin, without other recent changes to his medication and he denied the use of other new medicines. The patient went through surgery and the erection was resolved but presented fibrosis of the cavernous body which left him with erectile dysfunction. Since this event, the patient is no longer receiving Heparin and has had no other episodes of priapism. The prompt recognition of this side effect may decrease its morbidity and consequent impact on the quality of life. More studies are needed to better understand its pathophysiology.
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spelling Priapism Secondary to Low-Molecular-Weight Heparins: A Case ReportPriapismo Secundário a Heparinas de Baixo-Peso-Molecular: Um Caso ClínicoHeparinLow-Molecular-Weight/adverse effectsPriapism/chemically inducedHeparina de Baixo Peso Molecular/efeitos adversosPriapismo/induzido quimicamentePriapism may be a side effect of low-molecular-weight heparins, and its mechanism remains unknown. The authors present a clinical case of a 51-year-old male patient with oligodendroglioma. The patient presented ischemic priapism on the third month after starting tinzaparin, without other recent changes to his medication and he denied the use of other new medicines. The patient went through surgery and the erection was resolved but presented fibrosis of the cavernous body which left him with erectile dysfunction. Since this event, the patient is no longer receiving Heparin and has had no other episodes of priapism. The prompt recognition of this side effect may decrease its morbidity and consequent impact on the quality of life. More studies are needed to better understand its pathophysiology.O priapismo pode ser um efeito adverso das heparinas de baixo peso molecular, cuja fisiopatologia não é totalmente compreendida. Os autores apresentam o caso de um doente, do sexo masculino, 51 anos, com diagnóstico de oligodendroglioma. O doente apresentou um episódio de priapismo, no terceiro mês sob tinzaparina, sem nenhuma outra alteração recente da sua medicação habitual e com consumo de outros medicamentos negado. Foi submetido a cirurgia, com resolução do priapismo, mas apresentou fibrose sequelar dos corpos cavernosos, com consequente disfunção eréctil. Desde então o doente não retomou heparina e não apresentou novos episódios de priapismo. Um célere reconhecimento do quadro pode contribuir para menores sequelas, com consequente diminuição da morbilidade e impacto na qualidade de vida. Mais investigação é necessária para aumentar o conhecimento sobre a fisiopatologia desta situação.Ordem dos Médicos2022-08-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350Acta Médica Portuguesa; Vol. 36 No. 5 (2023): May; 358-360Acta Médica Portuguesa; Vol. 36 N.º 5 (2023): Maio; 358-3601646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350/6748Direitos de Autor (c) 2023 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessLiz-Pimenta, JoanaDias, NunoBarbosa, MiguelSousa, Marta2023-05-07T03:00:33Zoai:ojs.www.actamedicaportuguesa.com:article/18350Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:21:02.596681Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
Priapismo Secundário a Heparinas de Baixo-Peso-Molecular: Um Caso Clínico
title Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
spellingShingle Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
Liz-Pimenta, Joana
Heparin
Low-Molecular-Weight/adverse effects
Priapism/chemically induced
Heparina de Baixo Peso Molecular/efeitos adversos
Priapismo/induzido quimicamente
title_short Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
title_full Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
title_fullStr Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
title_full_unstemmed Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
title_sort Priapism Secondary to Low-Molecular-Weight Heparins: A Case Report
author Liz-Pimenta, Joana
author_facet Liz-Pimenta, Joana
Dias, Nuno
Barbosa, Miguel
Sousa, Marta
author_role author
author2 Dias, Nuno
Barbosa, Miguel
Sousa, Marta
author2_role author
author
author
dc.contributor.author.fl_str_mv Liz-Pimenta, Joana
Dias, Nuno
Barbosa, Miguel
Sousa, Marta
dc.subject.por.fl_str_mv Heparin
Low-Molecular-Weight/adverse effects
Priapism/chemically induced
Heparina de Baixo Peso Molecular/efeitos adversos
Priapismo/induzido quimicamente
topic Heparin
Low-Molecular-Weight/adverse effects
Priapism/chemically induced
Heparina de Baixo Peso Molecular/efeitos adversos
Priapismo/induzido quimicamente
description Priapism may be a side effect of low-molecular-weight heparins, and its mechanism remains unknown. The authors present a clinical case of a 51-year-old male patient with oligodendroglioma. The patient presented ischemic priapism on the third month after starting tinzaparin, without other recent changes to his medication and he denied the use of other new medicines. The patient went through surgery and the erection was resolved but presented fibrosis of the cavernous body which left him with erectile dysfunction. Since this event, the patient is no longer receiving Heparin and has had no other episodes of priapism. The prompt recognition of this side effect may decrease its morbidity and consequent impact on the quality of life. More studies are needed to better understand its pathophysiology.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-29
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/18350/6748
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2023 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2023 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 36 No. 5 (2023): May; 358-360
Acta Médica Portuguesa; Vol. 36 N.º 5 (2023): Maio; 358-360
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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