Severe hypokalemia in a child with mild gastroenteritis

Detalhes bibliográficos
Autor(a) principal: Faria, Catarina
Data de Publicação: 2019
Outros Autores: Ferreira, Carina, Sarmento, Alzira, Gonçalves, Sara, Rocha, Paula, Duarte, Carlos, Mota, Conceição
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338
Resumo: Background: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity.
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spelling Severe hypokalemia in a child with mild gastroenteritisHipocalémia grave numa criança com gastroenterite ligeiraCase ReportsBackground: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity.Introdução: A hipocalémia (potássio sérico inferior a 3.5 mmol/L) pode ser causada por vários mecanismos. A hipocalémia grave é uma emergência médica pelas importantes repercussões cardíacas que pode ter. Caso clínico: Uma rapariga de oito anos, previamente saudável, com crescimento normal e tensão arterial tendencialmente baixa, foi observada por dor abdominal persistente, anorexia e febre dois dias após recuperar de uma gastroenterite aguda ligeira. A avaliação bioquímica revelou hipocalémia grave (1.8 mmol/L), hipomagnesémia e alcalose metabólica. A rapariga foi admitida na Unidade de Cuidados Intensivos Pediátricos para correção dos distúrbios eletrolíticos, monitorização cardíaca e investigação. O ionograma urinário (urina pontual) revelou excreção inapropriada de potássio. A correção iónica foi alcançada através de suplementação intravenosa e oral associadas a espironolactona. A pesquisa de mutações para Síndrome de Gitelman foi positiva. Discussão/Conclusão: Perante uma discrepância entre o quadro clínico e a gravidade da hipocalémia, deverão ser suspeitadas e pesquisadas causas complexas deste distúrbio eletrolítico.Centro Hospitalar Universitário do Porto2019-10-14T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338eng2183-9417Faria, CatarinaFerreira, CarinaSarmento, AlziraGonçalves, SaraRocha, PaulaDuarte, CarlosMota, Conceiçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:32Zoai:ojs.revistas.rcaap.pt:article/15338Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:28.032310Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Severe hypokalemia in a child with mild gastroenteritis
Hipocalémia grave numa criança com gastroenterite ligeira
title Severe hypokalemia in a child with mild gastroenteritis
spellingShingle Severe hypokalemia in a child with mild gastroenteritis
Faria, Catarina
Case Reports
title_short Severe hypokalemia in a child with mild gastroenteritis
title_full Severe hypokalemia in a child with mild gastroenteritis
title_fullStr Severe hypokalemia in a child with mild gastroenteritis
title_full_unstemmed Severe hypokalemia in a child with mild gastroenteritis
title_sort Severe hypokalemia in a child with mild gastroenteritis
author Faria, Catarina
author_facet Faria, Catarina
Ferreira, Carina
Sarmento, Alzira
Gonçalves, Sara
Rocha, Paula
Duarte, Carlos
Mota, Conceição
author_role author
author2 Ferreira, Carina
Sarmento, Alzira
Gonçalves, Sara
Rocha, Paula
Duarte, Carlos
Mota, Conceição
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Faria, Catarina
Ferreira, Carina
Sarmento, Alzira
Gonçalves, Sara
Rocha, Paula
Duarte, Carlos
Mota, Conceição
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Background: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-14T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338
url https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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