Severe hypokalemia in a child with mild gastroenteritis
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338 |
Resumo: | Background: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity. |
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Severe hypokalemia in a child with mild gastroenteritisHipocalémia grave numa criança com gastroenterite ligeiraCase ReportsBackground: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity.Introdução: A hipocalémia (potássio sérico inferior a 3.5 mmol/L) pode ser causada por vários mecanismos. A hipocalémia grave é uma emergência médica pelas importantes repercussões cardíacas que pode ter. Caso clínico: Uma rapariga de oito anos, previamente saudável, com crescimento normal e tensão arterial tendencialmente baixa, foi observada por dor abdominal persistente, anorexia e febre dois dias após recuperar de uma gastroenterite aguda ligeira. A avaliação bioquímica revelou hipocalémia grave (1.8 mmol/L), hipomagnesémia e alcalose metabólica. A rapariga foi admitida na Unidade de Cuidados Intensivos Pediátricos para correção dos distúrbios eletrolíticos, monitorização cardíaca e investigação. O ionograma urinário (urina pontual) revelou excreção inapropriada de potássio. A correção iónica foi alcançada através de suplementação intravenosa e oral associadas a espironolactona. A pesquisa de mutações para Síndrome de Gitelman foi positiva. Discussão/Conclusão: Perante uma discrepância entre o quadro clínico e a gravidade da hipocalémia, deverão ser suspeitadas e pesquisadas causas complexas deste distúrbio eletrolítico.Centro Hospitalar Universitário do Porto2019-10-14T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338eng2183-9417Faria, CatarinaFerreira, CarinaSarmento, AlziraGonçalves, SaraRocha, PaulaDuarte, CarlosMota, Conceiçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:32Zoai:ojs.revistas.rcaap.pt:article/15338Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:28.032310Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Severe hypokalemia in a child with mild gastroenteritis Hipocalémia grave numa criança com gastroenterite ligeira |
title |
Severe hypokalemia in a child with mild gastroenteritis |
spellingShingle |
Severe hypokalemia in a child with mild gastroenteritis Faria, Catarina Case Reports |
title_short |
Severe hypokalemia in a child with mild gastroenteritis |
title_full |
Severe hypokalemia in a child with mild gastroenteritis |
title_fullStr |
Severe hypokalemia in a child with mild gastroenteritis |
title_full_unstemmed |
Severe hypokalemia in a child with mild gastroenteritis |
title_sort |
Severe hypokalemia in a child with mild gastroenteritis |
author |
Faria, Catarina |
author_facet |
Faria, Catarina Ferreira, Carina Sarmento, Alzira Gonçalves, Sara Rocha, Paula Duarte, Carlos Mota, Conceição |
author_role |
author |
author2 |
Ferreira, Carina Sarmento, Alzira Gonçalves, Sara Rocha, Paula Duarte, Carlos Mota, Conceição |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Faria, Catarina Ferreira, Carina Sarmento, Alzira Gonçalves, Sara Rocha, Paula Duarte, Carlos Mota, Conceição |
dc.subject.por.fl_str_mv |
Case Reports |
topic |
Case Reports |
description |
Background: Hypokalemia (serum potassium below 3.5 mmol/L) may be caused by several mechanisms. Severe hypokalemia must be immediately managed, as it can have important cardiac repercussions. Clinical case: A previously healthy eight-year-old female, with normal growth and normal-to-low blood pressure, was observed due to persistent abdominal pain, anorexia, and fever two days after overcoming a mild gastroenteritis episode. Serum biochemistry revealed severe hypokalemia (1.8 mmol/L), hypomagnesemia, and metabolic alkalosis. The patient was admitted to the Pediatric Intensive Care Unit for correction of electrolyte imbalance, cardiac monitoring, and investigation. Complementary studies included a spot urine ionogram that revealed inappropriate potassium wasting. Ionic correction was achieved by both intravenous and oral supplementation plus spironolactone. Genetic testing was positive for Gitelman syndrome. Discussion/Conclusion: Suspicion of complex causes should be raised and a comprehensive approach undertaken upon a discrepancy between clinical history and hypokalemia severity. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-14T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338 |
url |
https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15338 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2183-9417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1799130433245413376 |