SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/143607 |
Resumo: | Publisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritisdata from the EULAR COVAX physician-reported registryArthritis, JuvenileCOVID-19VaccinationRheumatologyImmunology and AllergyImmunologySDG 3 - Good Health and Well-beingPublisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.BACKGROUND: There is a lack of data on SARS-CoV-2 vaccination safety in children and young people (CYP) with rheumatic and musculoskeletal diseases (RMDs). Current vaccination guidance is based on data from adults with RMDs or CYP without RMDs. OBJECTIVES: To describe the safety of SARS-COV-2 vaccination in adolescents with inflammatory RMDs and adults with juvenile idiopathic arthritis (JIA). METHODS: We described patient characteristics, flares and adverse events (AEs) in adolescent cases under 18 with inflammatory RMDs and adult cases aged 18 or above with JIA submitted to the European Alliance of Associations for Rheumatology COVAX registry. RESULTS: A total of 110 cases were reported to the registry. Thirty-six adolescent cases were reported from four countries, most with JIA (42%). Over half (56%) reported early reactogenic-like AEs. One mild polyarthralgia flare and one serious AE of special interest (malaise) were reported. No CYP reported SARS-CoV-2 infection postvaccination.Seventy-four adult JIA cases were reported from 11 countries. Almost two-thirds (62%) reported early reactogenic-like AEs and two flares were reported (mild polyarthralgia and moderate uveitis). No serious AEs of special interest were reported among adults with JIA. Three female patients aged 20-30 years were diagnosed with SARS-CoV-2 postvaccination; all fully recovered. CONCLUSIONS: This is an important contribution to research on SARS-CoV-2 vaccine safety in adolescents with RMDs and adults with JIA. It is important to note the low frequency of disease flares, serious AEs and SARS-CoV-2 reinfection seen in both populations, although the dataset is limited by its size.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNLawson-Tovey, SaskiaMachado, Pedro M.Strangfeld, AnjaMateus, ElsaGossec, LaureCarmona, LoretoRaffeiner, BerndBulina, InitaClemente, DanielZepa, JulijaRodrigues, Ana M.Mariette, XavierHyrich, Kimme L.2022-09-08T22:49:04Z2022-07-012022-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/143607eng2044-6055PURE: 46124232https://doi.org/10.1136/rmdopen-2022-002322info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:22:10Zoai:run.unl.pt:10362/143607Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:51:02.766876Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis data from the EULAR COVAX physician-reported registry |
| title |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| spellingShingle |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis Lawson-Tovey, Saskia Arthritis, Juvenile COVID-19 Vaccination Rheumatology Immunology and Allergy Immunology SDG 3 - Good Health and Well-being |
| title_short |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| title_full |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| title_fullStr |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| title_full_unstemmed |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| title_sort |
SARS-CoV-2 vaccine safety in adolescents with inflammatory rheumatic and musculoskeletal diseases and adults with juvenile idiopathic arthritis |
| author |
Lawson-Tovey, Saskia |
| author_facet |
Lawson-Tovey, Saskia Machado, Pedro M. Strangfeld, Anja Mateus, Elsa Gossec, Laure Carmona, Loreto Raffeiner, Bernd Bulina, Inita Clemente, Daniel Zepa, Julija Rodrigues, Ana M. Mariette, Xavier Hyrich, Kimme L. |
| author_role |
author |
| author2 |
Machado, Pedro M. Strangfeld, Anja Mateus, Elsa Gossec, Laure Carmona, Loreto Raffeiner, Bernd Bulina, Inita Clemente, Daniel Zepa, Julija Rodrigues, Ana M. Mariette, Xavier Hyrich, Kimme L. |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Estudos de Doenças Crónicas (CEDOC) RUN |
| dc.contributor.author.fl_str_mv |
Lawson-Tovey, Saskia Machado, Pedro M. Strangfeld, Anja Mateus, Elsa Gossec, Laure Carmona, Loreto Raffeiner, Bernd Bulina, Inita Clemente, Daniel Zepa, Julija Rodrigues, Ana M. Mariette, Xavier Hyrich, Kimme L. |
| dc.subject.por.fl_str_mv |
Arthritis, Juvenile COVID-19 Vaccination Rheumatology Immunology and Allergy Immunology SDG 3 - Good Health and Well-being |
| topic |
Arthritis, Juvenile COVID-19 Vaccination Rheumatology Immunology and Allergy Immunology SDG 3 - Good Health and Well-being |
| description |
Publisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-09-08T22:49:04Z 2022-07-01 2022-07-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/143607 |
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http://hdl.handle.net/10362/143607 |
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eng |
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eng |
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2044-6055 PURE: 46124232 https://doi.org/10.1136/rmdopen-2022-002322 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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