The influence of Arsenic on the toxicity of carbon nanoparticles in bivalves

• Autor(a) principal: Freitas, Rosa
• Data de Publicação: 2018
• Outros Autores: Coppola, Francesca, De Marchi, Lucia, Codela, Valeria, Pretti, Carlo, Chiellini, Federica, Morelli, Andrea, Polese, Gianluca, Soares, Amadeu M. V. M., Figueira, Etelvina
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10773/27404
• topic: Mixture of contaminants; Metabolism; Oxidative stress; Neurotoxicity; Ruditapes philippinarum; Functionalized multi-walled carbon nanotubes

Although an increasing number of studies have been published on the effects of emergent pollutants such as carbon nanoparticles, there is still scarce information on the impact of these contaminants on marine organisms when acting in combination with classical pollutants such as meta(loid)s. The present study evaluated the impacts of Arsenic and Multi-Walled Carbon Nanotubes (MWCNTs) in the clam Ruditapes philippinarum, assessing the effects induced when both contaminants were acting individually (As, NP) and as a mixture (As+NP). Metabolic capacity (electron transport system activity), oxidative stress (antioxidant and biotransformation enzymes activity and cellular damage) and neurotoxicity (Acetylcholinesterase activity) biomarkers were evaluated inclams aftera28 daysexposure period.Theresults obtained showedthatthe accumulation ofAs was not affected by the presence of the NPs. Our results demonstrated that higher injuries were noticed in clams exposed to NPs, with higher metabolic depression and oxidative stress, regardless of the presence of As. Furthermore, higher neurotoxicity was observed in clams exposed to the combination of both contaminants in comparison to the effects of As and NPs individually.