Anaplastic mammary carcinoma in cat

Detalhes bibliográficos
Autor(a) principal: Soares, Maria
Data de Publicação: 2021
Outros Autores: Correia, Jorge Manuel de Jesus, Nascimento, Catarina, Ferreira, Fernando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/23414
Resumo: Research Areas: Veterinary Sciences
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spelling Anaplastic mammary carcinoma in catAnaplasticFeline mammary carcinomaClinicopathologicalImmunohistochemicalResearch Areas: Veterinary SciencesClinical, pathological, and immunohistochemical findings related to a feline mammary tumor with similar features to canine anaplastic mammary carcinoma are herein described for the first time. A female cat was presented for clinical evaluation with gastrointestinal signs, oedema, erythema, and painful lesion in the right inguinal region. Three weeks later, the mass had doubled in size and radiographic revaluation of the thoracic cavity revealed a metastatic pattern. Due to the poor prognosis and decline of the clinical status the owners decided for euthanasia. Post-mortem examination exposed a mammary tumoral mass with subcutaneous oedema, an enlargement of the right inguinal lymph node, and nodules in several organs. Histological analysis confirmed the presence of large pleomorphic epithelial cells, often grouped in small clusters with bizarre nuclei. Immunohistochemical study of the different lesions was performed and both primary tumor and regional metastasis showed tumor cells to be negative estrogen receptor alpha, positive progesterone receptor, positive HER-2, and positive pan-cytokeratin. Given that the clinical history was compatible with an inflammatory mammary carcinoma, the cyclooxygenase-2 expression levels were evaluated and presented a weak immunoreactivity. Regarding the distant metastatic lesions, tumor cells were negative for ER-α and PR and, positive both for HER-2 and pan-cytokeratin.MDPIRepositório da Universidade de LisboaSoares, MariaCorreia, Jorge Manuel de JesusNascimento, CatarinaFerreira, Fernando2022-02-06T23:07:08Z2021-05-042021-05-04T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/23414engSoares M, Correia J, Nascimento C, Ferreira F. 2021. Anaplastic mammary carcinoma in cat. Veterinary Sciences, 8(5):77. Doi: 10.3390/vetsci805007710.3390/vetsci80500772306-7381info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:52:58Zoai:www.repository.utl.pt:10400.5/23414Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:07:39.537804Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Anaplastic mammary carcinoma in cat
title Anaplastic mammary carcinoma in cat
spellingShingle Anaplastic mammary carcinoma in cat
Soares, Maria
Anaplastic
Feline mammary carcinoma
Clinicopathological
Immunohistochemical
title_short Anaplastic mammary carcinoma in cat
title_full Anaplastic mammary carcinoma in cat
title_fullStr Anaplastic mammary carcinoma in cat
title_full_unstemmed Anaplastic mammary carcinoma in cat
title_sort Anaplastic mammary carcinoma in cat
author Soares, Maria
author_facet Soares, Maria
Correia, Jorge Manuel de Jesus
Nascimento, Catarina
Ferreira, Fernando
author_role author
author2 Correia, Jorge Manuel de Jesus
Nascimento, Catarina
Ferreira, Fernando
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Soares, Maria
Correia, Jorge Manuel de Jesus
Nascimento, Catarina
Ferreira, Fernando
dc.subject.por.fl_str_mv Anaplastic
Feline mammary carcinoma
Clinicopathological
Immunohistochemical
topic Anaplastic
Feline mammary carcinoma
Clinicopathological
Immunohistochemical
description Research Areas: Veterinary Sciences
publishDate 2021
dc.date.none.fl_str_mv 2021-05-04
2021-05-04T00:00:00Z
2022-02-06T23:07:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/23414
url http://hdl.handle.net/10400.5/23414
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Soares M, Correia J, Nascimento C, Ferreira F. 2021. Anaplastic mammary carcinoma in cat. Veterinary Sciences, 8(5):77. Doi: 10.3390/vetsci8050077
10.3390/vetsci8050077
2306-7381
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron_str RCAAP
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