A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma

Detalhes bibliográficos
Autor(a) principal: Ramos, R
Data de Publicação: 2018
Outros Autores: Fernandes, JS, Almeida, M, Almeida, R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.23/1317
Resumo: Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.
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spelling A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System LymphomaLinfoma/quimioterapiaLinfoma/radioterapiaNeoplasias do Sistema Nervoso Central/quimioterapiaNeoplasias do Sistema Nervoso Central/radioterapiaPrimary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.Repositório Científico do Hospital de BragaRamos, RFernandes, JSAlmeida, MAlmeida, R2019-03-01T14:13:09Z2018-12-28T00:00:00Z2018-12-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.23/1317engActa Med Port. 2018 Dec 28;31(12):777-783.10.20344/amp.10198info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T09:03:13Zoai:repositorio.hospitaldebraga.pt:10400.23/1317Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:55:50.835576Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
spellingShingle A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
Ramos, R
Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
title_short A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_full A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_fullStr A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_full_unstemmed A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_sort A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
author Ramos, R
author_facet Ramos, R
Fernandes, JS
Almeida, M
Almeida, R
author_role author
author2 Fernandes, JS
Almeida, M
Almeida, R
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Hospital de Braga
dc.contributor.author.fl_str_mv Ramos, R
Fernandes, JS
Almeida, M
Almeida, R
dc.subject.por.fl_str_mv Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
topic Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
description Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-28T00:00:00Z
2018-12-28T00:00:00Z
2019-03-01T14:13:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.23/1317
url http://hdl.handle.net/10400.23/1317
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Med Port. 2018 Dec 28;31(12):777-783.
10.20344/amp.10198
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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