A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.23/1317 |
Resumo: | Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out. |
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A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System LymphomaLinfoma/quimioterapiaLinfoma/radioterapiaNeoplasias do Sistema Nervoso Central/quimioterapiaNeoplasias do Sistema Nervoso Central/radioterapiaPrimary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.Repositório Científico do Hospital de BragaRamos, RFernandes, JSAlmeida, MAlmeida, R2019-03-01T14:13:09Z2018-12-28T00:00:00Z2018-12-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.23/1317engActa Med Port. 2018 Dec 28;31(12):777-783.10.20344/amp.10198info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T09:03:13Zoai:repositorio.hospitaldebraga.pt:10400.23/1317Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:55:50.835576Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
title |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
spellingShingle |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma Ramos, R Linfoma/quimioterapia Linfoma/radioterapia Neoplasias do Sistema Nervoso Central/quimioterapia Neoplasias do Sistema Nervoso Central/radioterapia |
title_short |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
title_full |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
title_fullStr |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
title_full_unstemmed |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
title_sort |
A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma |
author |
Ramos, R |
author_facet |
Ramos, R Fernandes, JS Almeida, M Almeida, R |
author_role |
author |
author2 |
Fernandes, JS Almeida, M Almeida, R |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Hospital de Braga |
dc.contributor.author.fl_str_mv |
Ramos, R Fernandes, JS Almeida, M Almeida, R |
dc.subject.por.fl_str_mv |
Linfoma/quimioterapia Linfoma/radioterapia Neoplasias do Sistema Nervoso Central/quimioterapia Neoplasias do Sistema Nervoso Central/radioterapia |
topic |
Linfoma/quimioterapia Linfoma/radioterapia Neoplasias do Sistema Nervoso Central/quimioterapia Neoplasias do Sistema Nervoso Central/radioterapia |
description |
Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-28T00:00:00Z 2018-12-28T00:00:00Z 2019-03-01T14:13:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.23/1317 |
url |
http://hdl.handle.net/10400.23/1317 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Med Port. 2018 Dec 28;31(12):777-783. 10.20344/amp.10198 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130427007434752 |