Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications

Detalhes bibliográficos
Autor(a) principal: Zielińska, Aleksandra
Data de Publicação: 2021
Outros Autores: Szalata, Marlena, Gorczyński, Adam, Karczewski, Jacek, Eder, Piotr, Severino, Patrícia, Cabeda, JM, Souto, Eliana B., Słomski, Ryszard
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10284/9783
Resumo: Physicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals’ potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.
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spelling Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applicationsNanoparticlesCancer diagnosisTreatment of cancerNanotherapeuticsTherapeutic nanoparticles CancersPhysicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals’ potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.Repositório Institucional da Universidade Fernando PessoaZielińska, AleksandraSzalata, MarlenaGorczyński, AdamKarczewski, JacekEder, PiotrSeverino, PatríciaCabeda, JMSouto, Eliana B.Słomski, Ryszard2021-04-26T08:29:07Z2021-04-01T00:00:00Z2021-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10284/9783eng2072-669410.3390/cancers13081896info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-06T02:09:10Zoai:bdigital.ufp.pt:10284/9783Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:46:39.781755Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
title Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
spellingShingle Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
Zielińska, Aleksandra
Nanoparticles
Cancer diagnosis
Treatment of cancer
Nanotherapeutics
Therapeutic nanoparticles Cancers
title_short Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
title_full Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
title_fullStr Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
title_full_unstemmed Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
title_sort Cancer nanopharmaceuticals: physicochemical characterization and in vitro/in vivo applications
author Zielińska, Aleksandra
author_facet Zielińska, Aleksandra
Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, JM
Souto, Eliana B.
Słomski, Ryszard
author_role author
author2 Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, JM
Souto, Eliana B.
Słomski, Ryszard
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Institucional da Universidade Fernando Pessoa
dc.contributor.author.fl_str_mv Zielińska, Aleksandra
Szalata, Marlena
Gorczyński, Adam
Karczewski, Jacek
Eder, Piotr
Severino, Patrícia
Cabeda, JM
Souto, Eliana B.
Słomski, Ryszard
dc.subject.por.fl_str_mv Nanoparticles
Cancer diagnosis
Treatment of cancer
Nanotherapeutics
Therapeutic nanoparticles Cancers
topic Nanoparticles
Cancer diagnosis
Treatment of cancer
Nanotherapeutics
Therapeutic nanoparticles Cancers
description Physicochemical, pharmacokinetic, and biopharmaceutical characterization tools play a key role in the assessment of nanopharmaceuticals’ potential imaging analysis and for site-specific delivery of anti-cancers to neoplastic cells/tissues. If diagnostic tools and therapeutic approaches are combined in one single nanoparticle, a new platform called nanotheragnostics is generated. Several analytical technologies allow us to characterize nanopharmaceuticals and nanoparticles and their properties so that they can be properly used in cancer therapy. This paper describes the role of multifunctional nanoparticles in cancer diagnosis and treatment, describing how nanotheragnostics can be useful in modern chemotherapy, and finally, the challenges associated with the commercialization of nanoparticles for cancer therapy.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-26T08:29:07Z
2021-04-01T00:00:00Z
2021-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10284/9783
url http://hdl.handle.net/10284/9783
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2072-6694
10.3390/cancers13081896
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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