Genetics. Sowing the seeds of centromeres.

Detalhes bibliográficos
Autor(a) principal: Jansen, L. E. T.
Data de Publicação: 2012
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/615
Resumo: The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior?
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spelling Genetics. Sowing the seeds of centromeres.AnimalsCentromereDrosophilaHistonesThe centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior?American Association for the Advancement of ScienceARCAJansen, L. E. T.2016-05-24T11:10:36Z2012-01-202012-01-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/615engJansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300.10.1126/science.1218162info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:00Zoai:arca.igc.gulbenkian.pt:10400.7/615Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:51.590949Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Genetics. Sowing the seeds of centromeres.
title Genetics. Sowing the seeds of centromeres.
spellingShingle Genetics. Sowing the seeds of centromeres.
Jansen, L. E. T.
Animals
Centromere
Drosophila
Histones
title_short Genetics. Sowing the seeds of centromeres.
title_full Genetics. Sowing the seeds of centromeres.
title_fullStr Genetics. Sowing the seeds of centromeres.
title_full_unstemmed Genetics. Sowing the seeds of centromeres.
title_sort Genetics. Sowing the seeds of centromeres.
author Jansen, L. E. T.
author_facet Jansen, L. E. T.
author_role author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Jansen, L. E. T.
dc.subject.por.fl_str_mv Animals
Centromere
Drosophila
Histones
topic Animals
Centromere
Drosophila
Histones
description The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior?
publishDate 2012
dc.date.none.fl_str_mv 2012-01-20
2012-01-20T00:00:00Z
2016-05-24T11:10:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/615
url http://hdl.handle.net/10400.7/615
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Jansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300.
10.1126/science.1218162
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Association for the Advancement of Science
publisher.none.fl_str_mv American Association for the Advancement of Science
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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