Genetics. Sowing the seeds of centromeres.
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.7/615 |
Resumo: | The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior? |
id |
RCAP_7800be44c0c9ec8c4118347d9d3dab9c |
---|---|
oai_identifier_str |
oai:arca.igc.gulbenkian.pt:10400.7/615 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Genetics. Sowing the seeds of centromeres.AnimalsCentromereDrosophilaHistonesThe centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior?American Association for the Advancement of ScienceARCAJansen, L. E. T.2016-05-24T11:10:36Z2012-01-202012-01-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/615engJansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300.10.1126/science.1218162info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:00Zoai:arca.igc.gulbenkian.pt:10400.7/615Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:51.590949Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Genetics. Sowing the seeds of centromeres. |
title |
Genetics. Sowing the seeds of centromeres. |
spellingShingle |
Genetics. Sowing the seeds of centromeres. Jansen, L. E. T. Animals Centromere Drosophila Histones |
title_short |
Genetics. Sowing the seeds of centromeres. |
title_full |
Genetics. Sowing the seeds of centromeres. |
title_fullStr |
Genetics. Sowing the seeds of centromeres. |
title_full_unstemmed |
Genetics. Sowing the seeds of centromeres. |
title_sort |
Genetics. Sowing the seeds of centromeres. |
author |
Jansen, L. E. T. |
author_facet |
Jansen, L. E. T. |
author_role |
author |
dc.contributor.none.fl_str_mv |
ARCA |
dc.contributor.author.fl_str_mv |
Jansen, L. E. T. |
dc.subject.por.fl_str_mv |
Animals Centromere Drosophila Histones |
topic |
Animals Centromere Drosophila Histones |
description |
The centromere is a chromatin-based platform that accumulates microtubule-binding proteins that drive chromosome segregation during cell division. Despite their size (on the order of megabases of DNA in mammals) and conserved role, centromeres have the remarkable capacity to leave their usual comfort zone and to reform at a new chromosomal site (1). Although found rarely, these so-called neocentromeres are by most measures bona fide and segregate chromosomes with high fidelity. What accounts for this nomadic behavior? |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-01-20 2012-01-20T00:00:00Z 2016-05-24T11:10:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.7/615 |
url |
http://hdl.handle.net/10400.7/615 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Jansen, L. E. T. (2012). Genetics. Sowing the seeds of centromeres. Science, 335(6066), 299–300. 10.1126/science.1218162 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
American Association for the Advancement of Science |
publisher.none.fl_str_mv |
American Association for the Advancement of Science |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130573786054656 |