Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/36850 https://doi.org/10.1007/s00414-016-1497-y |
Resumo: | We analyzed the GlobalFiler short tandem repeat (STR) loci for 152 and 70 unrelated individuals from Angolan and Guinean immigrant populations inhabiting Southern Portugal, respectively. After Bonferroni correction, no significant deviations from the Hardy-Weinberg equilibrium and linkage disequilibrium were detected for either population. For the Angolan population, SE33 was the most informative marker. In contrast, D5S818 and D13S317 were the least informative loci. The combined power of discrimination was 99.9999999999999999999999961907%. For the Guinean population, SE33 and D21S1 were the most informative loci, while D13S317 was the least. The combined power of discrimination was 99.99999999999999999999997915%. No significant differences were observed between Angolan, Guinean, and Afro-American populations for any of the analyzed STRs. The South African population presented significant differences at D22S1045 and D10S1248 when compared to Angola, and at D22S1045 when compared to Guinea-Bissau. The MDS plot and neighbor-joining tree analysis revealed that Angolan and Guinean populations are genetically close to African-American and South African populations, and genetically different from Korean, Mexican, European (including American-Caucasian), and Middle Eastern populations. |
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Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern PortugalContinental Population GroupsDNA FingerprintingEthnic GroupsGene FrequencyGenetic LociHumansPolymerase Chain ReactionPortugalEmigrants and ImmigrantsGenetics, PopulationMicrosatellite RepeatsWe analyzed the GlobalFiler short tandem repeat (STR) loci for 152 and 70 unrelated individuals from Angolan and Guinean immigrant populations inhabiting Southern Portugal, respectively. After Bonferroni correction, no significant deviations from the Hardy-Weinberg equilibrium and linkage disequilibrium were detected for either population. For the Angolan population, SE33 was the most informative marker. In contrast, D5S818 and D13S317 were the least informative loci. The combined power of discrimination was 99.9999999999999999999999961907%. For the Guinean population, SE33 and D21S1 were the most informative loci, while D13S317 was the least. The combined power of discrimination was 99.99999999999999999999997915%. No significant differences were observed between Angolan, Guinean, and Afro-American populations for any of the analyzed STRs. The South African population presented significant differences at D22S1045 and D10S1248 when compared to Angola, and at D22S1045 when compared to Guinea-Bissau. The MDS plot and neighbor-joining tree analysis revealed that Angolan and Guinean populations are genetically close to African-American and South African populations, and genetically different from Korean, Mexican, European (including American-Caucasian), and Middle Eastern populations.eu-repo/semantics/submittedVersionSpringer2021-06-22T08:43:47Z2021-06-222017-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/36850http://hdl.handle.net/10400.26/36850https://doi.org/10.1007/s00414-016-1497-yengGuerreiro, S., Ribeiro, T., Porto, M. J., Carneiro de Sousa, M. J., & Dario, P. (2017). Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal. International journal of legal medicine, 131(2), 365–3681437-1596https://link.springer.com/article/10.1007%2Fs00414-016-1497-yGuerreiro, SoraiaRibeiro, TeresaPorto, Maria JoãoCarneiro De Sousa Pinto Costa, Maria JoséDario, Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:21:43Zoai:comum.rcaap.pt:10400.26/36850Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:40.833101Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
title |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
spellingShingle |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal Guerreiro, Soraia Continental Population Groups DNA Fingerprinting Ethnic Groups Gene Frequency Genetic Loci Humans Polymerase Chain Reaction Portugal Emigrants and Immigrants Genetics, Population Microsatellite Repeats |
title_short |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
title_full |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
title_fullStr |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
title_full_unstemmed |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
title_sort |
Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal |
author |
Guerreiro, Soraia |
author_facet |
Guerreiro, Soraia Ribeiro, Teresa Porto, Maria João Carneiro De Sousa Pinto Costa, Maria José Dario, Paulo |
author_role |
author |
author2 |
Ribeiro, Teresa Porto, Maria João Carneiro De Sousa Pinto Costa, Maria José Dario, Paulo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Guerreiro, Soraia Ribeiro, Teresa Porto, Maria João Carneiro De Sousa Pinto Costa, Maria José Dario, Paulo |
dc.subject.por.fl_str_mv |
Continental Population Groups DNA Fingerprinting Ethnic Groups Gene Frequency Genetic Loci Humans Polymerase Chain Reaction Portugal Emigrants and Immigrants Genetics, Population Microsatellite Repeats |
topic |
Continental Population Groups DNA Fingerprinting Ethnic Groups Gene Frequency Genetic Loci Humans Polymerase Chain Reaction Portugal Emigrants and Immigrants Genetics, Population Microsatellite Repeats |
description |
We analyzed the GlobalFiler short tandem repeat (STR) loci for 152 and 70 unrelated individuals from Angolan and Guinean immigrant populations inhabiting Southern Portugal, respectively. After Bonferroni correction, no significant deviations from the Hardy-Weinberg equilibrium and linkage disequilibrium were detected for either population. For the Angolan population, SE33 was the most informative marker. In contrast, D5S818 and D13S317 were the least informative loci. The combined power of discrimination was 99.9999999999999999999999961907%. For the Guinean population, SE33 and D21S1 were the most informative loci, while D13S317 was the least. The combined power of discrimination was 99.99999999999999999999997915%. No significant differences were observed between Angolan, Guinean, and Afro-American populations for any of the analyzed STRs. The South African population presented significant differences at D22S1045 and D10S1248 when compared to Angola, and at D22S1045 when compared to Guinea-Bissau. The MDS plot and neighbor-joining tree analysis revealed that Angolan and Guinean populations are genetically close to African-American and South African populations, and genetically different from Korean, Mexican, European (including American-Caucasian), and Middle Eastern populations. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-01T00:00:00Z 2021-06-22T08:43:47Z 2021-06-22 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/36850 http://hdl.handle.net/10400.26/36850 https://doi.org/10.1007/s00414-016-1497-y |
url |
http://hdl.handle.net/10400.26/36850 https://doi.org/10.1007/s00414-016-1497-y |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Guerreiro, S., Ribeiro, T., Porto, M. J., Carneiro de Sousa, M. J., & Dario, P. (2017). Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal. International journal of legal medicine, 131(2), 365–368 1437-1596 https://link.springer.com/article/10.1007%2Fs00414-016-1497-y |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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