Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications

Detalhes bibliográficos
Autor(a) principal: Coimbra, Patrícia
Data de Publicação: 2010
Outros Autores: Ferreira, Paula, Sousa, Hermínio C. de, Batista, Patrícia Sofia Pinhanços, Rodrigues, Miguel, Correia, Ilídio Joaquim Sobreira, Gil, Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/4627
Resumo: In this work, porous scaffolds obtained from the freeze-drying of pectin/chitosan polyelectrolyte complexes were prepared and characterized by FTIR, SEM and weight loss studies. Additionally, the cytotoxicity of the prepared scaffolds was evaluated in vitro, using human osteoblast cells. The results obtained showed that cells adhered to scaffolds and proliferated. The study also confirmed that the degradation by-products of pectin/chitosan scaffold are noncytotoxic.
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spelling Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applicationsPolymeric scaffoldPolyelectrolyte complexesCytotoxicityOsteoblastsIn this work, porous scaffolds obtained from the freeze-drying of pectin/chitosan polyelectrolyte complexes were prepared and characterized by FTIR, SEM and weight loss studies. Additionally, the cytotoxicity of the prepared scaffolds was evaluated in vitro, using human osteoblast cells. The results obtained showed that cells adhered to scaffolds and proliferated. The study also confirmed that the degradation by-products of pectin/chitosan scaffold are noncytotoxic.ElsevieruBibliorumCoimbra, PatríciaFerreira, PaulaSousa, Hermínio C. deBatista, Patrícia Sofia PinhançosRodrigues, MiguelCorreia, Ilídio Joaquim SobreiraGil, Maria2018-03-19T10:37:36Z2010-10-162010-10-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/4627engCoimbra, P., Ferreira, P., Sousa, H.C., Batista, P., Rodrigues, M.A., Correia, I.J. e Gil, M. H. (2011) “Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications”, International Journal of Biological Macromolecules, Vol. 48 (1), pp. 112-11810.1016/j.ijbiomac.2010.10.006metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-07T02:30:44Zoai:ubibliorum.ubi.pt:10400.6/4627Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:45:41.465711Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
title Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
spellingShingle Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
Coimbra, Patrícia
Polymeric scaffold
Polyelectrolyte complexes
Cytotoxicity
Osteoblasts
title_short Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
title_full Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
title_fullStr Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
title_full_unstemmed Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
title_sort Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications
author Coimbra, Patrícia
author_facet Coimbra, Patrícia
Ferreira, Paula
Sousa, Hermínio C. de
Batista, Patrícia Sofia Pinhanços
Rodrigues, Miguel
Correia, Ilídio Joaquim Sobreira
Gil, Maria
author_role author
author2 Ferreira, Paula
Sousa, Hermínio C. de
Batista, Patrícia Sofia Pinhanços
Rodrigues, Miguel
Correia, Ilídio Joaquim Sobreira
Gil, Maria
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Coimbra, Patrícia
Ferreira, Paula
Sousa, Hermínio C. de
Batista, Patrícia Sofia Pinhanços
Rodrigues, Miguel
Correia, Ilídio Joaquim Sobreira
Gil, Maria
dc.subject.por.fl_str_mv Polymeric scaffold
Polyelectrolyte complexes
Cytotoxicity
Osteoblasts
topic Polymeric scaffold
Polyelectrolyte complexes
Cytotoxicity
Osteoblasts
description In this work, porous scaffolds obtained from the freeze-drying of pectin/chitosan polyelectrolyte complexes were prepared and characterized by FTIR, SEM and weight loss studies. Additionally, the cytotoxicity of the prepared scaffolds was evaluated in vitro, using human osteoblast cells. The results obtained showed that cells adhered to scaffolds and proliferated. The study also confirmed that the degradation by-products of pectin/chitosan scaffold are noncytotoxic.
publishDate 2010
dc.date.none.fl_str_mv 2010-10-16
2010-10-16T00:00:00Z
2018-03-19T10:37:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/4627
url http://hdl.handle.net/10400.6/4627
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Coimbra, P., Ferreira, P., Sousa, H.C., Batista, P., Rodrigues, M.A., Correia, I.J. e Gil, M. H. (2011) “Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications”, International Journal of Biological Macromolecules, Vol. 48 (1), pp. 112-118
10.1016/j.ijbiomac.2010.10.006
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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