Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences

Detalhes bibliográficos
Autor(a) principal: Morais, Paulo
Data de Publicação: 2022
Outros Autores: Trovão, Nídia S, Abecasis, Ana B, Parreira, Ricardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/136260
Resumo: Copyright © 2022 Elsevier B.V. All rights reserved.
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spelling Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequencesAmino Acid SequenceAnimalsCulicidaeGenetic VariationGenome, ViralNidovirales/geneticsPhylogenyGeneticsEcology, Evolution, Behavior and SystematicsVirologySDG 15 - Life on LandSDG 3 - Good Health and Well-beingCopyright © 2022 Elsevier B.V. All rights reserved.Research on the recently established Mesoniviridae family (Order Nidovirales), RNA genome insect-specific viruses, has been steadily growing in the last decade. However, after the last detailed phylogenetic characterization of mesoniviruses in 2014, numerous new sequences, even in organisms other than mosquitos, have been identified and characterized. In this study, we analyzed nucleotide and protein sequences of mesoniviruses with a wide range of molecular tools including genetic distance, Shannon entropy, selective pressure analysis, polymorphism identification, principal coordinate analysis, likelihood mapping and phylodynamic reconstruction. We also sought to revaluate new mesoniviruses sequence positions within the family, proposing a taxonomic revision. The different sub-lineages of mosquito mesoniviruses sequences presented low sequence diversity and entropy, with incongruences to the existing taxonomy being found after an extensive phylogenetic characterization. High sequence discrepancy and differences in genome organization were found between mosquito mesoniviruses and other mesoniviruses, so their future classification, as other meso-like viruses that are found in other organisms, should be approached with caution. No evidence of frequent recombination was found, and mesonivirus genomes seem to evolve under strong purifying selection. Insufficient data by root-to-tip analysis did not yet allow for an adequate phylogeographic reconstruction.Instituto de Higiene e Medicina Tropical (IHMT)TB, HIV and opportunistic diseases and pathogens (THOP)Global Health and Tropical Medicine (GHTM)Vector borne diseases and pathogens (VBD)RUNMorais, PauloTrovão, Nídia SAbecasis, Ana BParreira, Ricardo2022-04-11T22:37:05Z2022-052022-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/136260eng0168-1702PURE: 43046907https://doi.org/10.1016/j.virusres.2022.198727info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:26Zoai:run.unl.pt:10362/136260Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:39.945293Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
title Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
spellingShingle Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
Morais, Paulo
Amino Acid Sequence
Animals
Culicidae
Genetic Variation
Genome, Viral
Nidovirales/genetics
Phylogeny
Genetics
Ecology, Evolution, Behavior and Systematics
Virology
SDG 15 - Life on Land
SDG 3 - Good Health and Well-being
title_short Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
title_full Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
title_fullStr Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
title_full_unstemmed Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
title_sort Readdressing the genetic diversity and taxonomy of the Mesoniviridae family, as well as its relationships with other nidoviruses and putative mesonivirus-like viral sequences
author Morais, Paulo
author_facet Morais, Paulo
Trovão, Nídia S
Abecasis, Ana B
Parreira, Ricardo
author_role author
author2 Trovão, Nídia S
Abecasis, Ana B
Parreira, Ricardo
author2_role author
author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
TB, HIV and opportunistic diseases and pathogens (THOP)
Global Health and Tropical Medicine (GHTM)
Vector borne diseases and pathogens (VBD)
RUN
dc.contributor.author.fl_str_mv Morais, Paulo
Trovão, Nídia S
Abecasis, Ana B
Parreira, Ricardo
dc.subject.por.fl_str_mv Amino Acid Sequence
Animals
Culicidae
Genetic Variation
Genome, Viral
Nidovirales/genetics
Phylogeny
Genetics
Ecology, Evolution, Behavior and Systematics
Virology
SDG 15 - Life on Land
SDG 3 - Good Health and Well-being
topic Amino Acid Sequence
Animals
Culicidae
Genetic Variation
Genome, Viral
Nidovirales/genetics
Phylogeny
Genetics
Ecology, Evolution, Behavior and Systematics
Virology
SDG 15 - Life on Land
SDG 3 - Good Health and Well-being
description Copyright © 2022 Elsevier B.V. All rights reserved.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-11T22:37:05Z
2022-05
2022-05-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/136260
url http://hdl.handle.net/10362/136260
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0168-1702
PURE: 43046907
https://doi.org/10.1016/j.virusres.2022.198727
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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