The value of abdominal fat biopsy in the diagnostic search for amyloid substance

• Autor(a) principal: Ascensão, Margarida
• Data de Publicação: 1997
• Outros Autores: Figueiredo, Helena, Parente, Francisco, Matos, Rita, Alexandrino, Borges, Serra e Silva, Políbio
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/2227
• topic: amiloidose sistémica; biópsia de gordura abdominal; diagnóstico; permanganato de potássio; systemic amyloidosis; abdominal fat biopsy; diagnosis; potassium permanganate

Considering their interest in amyloidosis, particu­ larly of lhe primary type (AL), and the results descri­bed in the literature, that indicate a high sensitivity yield in the localization of amyloid substance in ab­dominalfat biopsy, the authors developed and appli­ed this technique, particularly after 1990. They analyse the results obtained from forty-eight patients submitted to this study by abdominal subcu­taneous fat biopsy, appreciating the technique sensi­tivity and specificity and dedicating special attention to the criteria that lead to its execution. Also they dis­cuss the vahle of the potassium permanganate test. With this work, thea uthors wish to communicate their experience and evahlate the criteria for theamyloid substance search, contributing to the increase in diag­nosis of amyloidosis by use of a simple technique.