RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS

Detalhes bibliográficos
Autor(a) principal: Pinto Sousa, Pedro
Data de Publicação: 2022
Outros Autores: Sá Pinto, Pedro, Machado, Rui, Almeida, Rui
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48750/acv.172
Resumo: Introduction: Renal autotransplantation (RA) is a safe and effective procedure to reconstruct the urinary tract which first successful surgery was performed by Hardy in 1963. The main indications reported to perform a RA generally include renovascular disease, ureteral pathologies and neoplastic disease. Furthermore, RA may be useful as an ultimate recourse in preventing kidney loss in highly selected patients, especially when conventional methods have failed. Materials and Methods: The authors describe four total different situations where the RA was the key solution for the pathology initially presented. Clinical case I – A 52 years old male with a previous history of left nephrectomy due to a preceding exacerbation of his basal Crohn's disease and also a right ureter cutaneostomie, presented now with repetitive urinary tract infections that led to renal function impairment; Clinical case II – A 57 years old female with the diagnosis of renal artery aneurysm while being studied as a potential kidney donor; Clinical case III – A 49 years old male admitted in the emergency room after a penetrating trauma which conditioned bowel and ureteral lesions with postoperative consecutive and recurrent peritoneal infections that compounded a necessity for a left ureterostomy, that the patient vehemently refused; Clinical case IV – A 24 years old female with the diagnosis of Nutcracker syndrome identified after being studied regarding repetitive urgency admissions with frank haematuria. Results: Every patient was submitted to laparoscopic nephrectomy, ex-vivo reconstruction, if necessary, and kidney transplantation to the iliac fossa. The interventions were uneventful and only one patient faced a minor post-operative complication (surgical wound dehiscende). We performed an ultrasound and renal scintigraphy evaluation on following days after each procedure to attest normal renal perfusion. Discussion: The RA were conducted in two patients with ureteral cutaneostomie because there was no viable alternative but kidney loss. The other two clinical cases were treated with RA because they concerned a complex renovascular disease (one arterial and the other venous). Despite the existence of an endovascular option for these patients, long term follow-up studies are still lacking. Conclusion: The RA is a viable option in specific situations for kidney salvage. The recent development of laparoscopic nephrectomy significantly decreased the surgical hostility to the patient and promoted the RA as a value option for the treatment of complex vascular pathologies, traumatic disease and specific medical situations. It represents a credible alternative with attested results already described in the literature thus requiring a vast Institutional experience withconventional renal transplantation.  
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spelling RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONSAUTOTRANSPLANTE RENAL: UMA SOLUÇÃO PARA SITUAÇÕES COMPLEXAS DIVERSASRenal auto-transplantNutcracker syndromeRenal artery aneurysmEx-vivo repairlaparoscopyAutotransplante renallaparoscopiaSíndrome de nutcrackerAneurisma da artéria renalReparo ex vivoIntroduction: Renal autotransplantation (RA) is a safe and effective procedure to reconstruct the urinary tract which first successful surgery was performed by Hardy in 1963. The main indications reported to perform a RA generally include renovascular disease, ureteral pathologies and neoplastic disease. Furthermore, RA may be useful as an ultimate recourse in preventing kidney loss in highly selected patients, especially when conventional methods have failed. Materials and Methods: The authors describe four total different situations where the RA was the key solution for the pathology initially presented. Clinical case I – A 52 years old male with a previous history of left nephrectomy due to a preceding exacerbation of his basal Crohn's disease and also a right ureter cutaneostomie, presented now with repetitive urinary tract infections that led to renal function impairment; Clinical case II – A 57 years old female with the diagnosis of renal artery aneurysm while being studied as a potential kidney donor; Clinical case III – A 49 years old male admitted in the emergency room after a penetrating trauma which conditioned bowel and ureteral lesions with postoperative consecutive and recurrent peritoneal infections that compounded a necessity for a left ureterostomy, that the patient vehemently refused; Clinical case IV – A 24 years old female with the diagnosis of Nutcracker syndrome identified after being studied regarding repetitive urgency admissions with frank haematuria. Results: Every patient was submitted to laparoscopic nephrectomy, ex-vivo reconstruction, if necessary, and kidney transplantation to the iliac fossa. The interventions were uneventful and only one patient faced a minor post-operative complication (surgical wound dehiscende). We performed an ultrasound and renal scintigraphy evaluation on following days after each procedure to attest normal renal perfusion. Discussion: The RA were conducted in two patients with ureteral cutaneostomie because there was no viable alternative but kidney loss. The other two clinical cases were treated with RA because they concerned a complex renovascular disease (one arterial and the other venous). Despite the existence of an endovascular option for these patients, long term follow-up studies are still lacking. Conclusion: The RA is a viable option in specific situations for kidney salvage. The recent development of laparoscopic nephrectomy significantly decreased the surgical hostility to the patient and promoted the RA as a value option for the treatment of complex vascular pathologies, traumatic disease and specific medical situations. It represents a credible alternative with attested results already described in the literature thus requiring a vast Institutional experience withconventional renal transplantation.  Introdução: O autotransplante renal (RA) é um procedimento seguro e eficaz, utilizado em patologias que requeiram reconstrução do trato urinário, cujo primeira intervenção foi descrita por Hardy em 1963. As principais indicações são doença renovascular, patologias ureterais e doença neoplásica. O RA poderá ainda ser útil em casos selecionados, como último recurso na prevenção de perda renal, especialmente quando os métodos convencionais não tiveram sucesso. Materiais e métodos: Os autores pretendem descrever quatro diferentes situações em que o RA foi a melhor solução para a patologia apresentada pelos doentes. Caso clínico I — Doente do sexo masculino, 52 anos de idade, com história de nefrectomia esquerda prévia e urete- rostomia direita, no contexto de exacerbação da sua doença de Crohn. Apresentava-se agora, recentemente, com infeções urinárias de repetição e consequente disfunção renal; Caso clínico II — Doente do sexo feminino, 57 anos de idade, a quem foi diagnosticado um aneurisma da artéria renal enquanto era estudada como potencial dadora para transplante renal; Caso clínico III — Doente do sexo masculino, 49 anos de idade, admitido no Serviço de urgência vítima de trauma penetrante com atingimento abdominal e consequentes lesões ureterais e do trato intestinal. Submetido a laparo- tomia com reconstrução das mesmas, mas posteriores peritonites de repetição que condicionaram necessidade de ureterostomia que o doente recusava; Caso clínico IV — Doente do sexo feminino, 24 anos de idade, com o diagnóstico de Síndrome de Nutcraker após estudo realizado na sequência de admissão no Serviço de urgência com hematúria franca. Resultados: Todos os doentes foram submetidos a RA. As intervenções cirúrgicas decorreram sem intercorrências com apenas um doente a ter desenvolvido uma complicação (deiscência de ferida cirúrgica) no período pós-operatório. Foi realizado ecoDoppler e cintigrafia renal nos dias subsequentes ao procedimento que atestou a normal perfusão dos rins transplantados. Discussão: O RA foi realizado em dois doentes no contexto de lesões ureterais e perante a ausência de tratamento viável alternativo que não a perda do rim. Os outros dois casos ocorreram no contexto de patologias renovasculares complexas (uma arterial e outra venosa). Apesar da existência de opções endovasculares para estes casos, a publicação de resultados de seguimento a longo prazo ainda é escassa. Conclusão: O RA é uma opção viável em situações específicas em que é imperial a salvação do rim. Os avanços recentes com nefrectomia laparoscópica vieram reduzir de forma significativa a agressividade do procedimento cirúrgico, promovendo o RA como uma arma de tratamento de real valor no tratamento de patologias vasculares complexas, doença renovascular e ureteral traumática bem como situações médicas específicas. O RA representa assim, uma alternativa credível com resultados demonstrados e publicados, exigindo, contudo, ser realizado num Centro com elevada experiência institucional.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2022-03-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.172oai:ojs.acvjournal.com:article/172Angiologia e Cirurgia Vascular; Vol. 17 No. 4 (2021): December; 339-343Angiologia e Cirurgia Vascular; Vol. 17 N.º 4 (2021): Dezembro; 339-3432183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://acvjournal.com/index.php/acv/article/view/172https://doi.org/10.48750/acv.172http://acvjournal.com/index.php/acv/article/view/172/277Copyright (c) 2022 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessPinto Sousa, PedroSá Pinto, PedroMachado, RuiAlmeida, Rui2022-05-23T15:10:04Zoai:ojs.acvjournal.com:article/172Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T14:57:33.617346Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
AUTOTRANSPLANTE RENAL: UMA SOLUÇÃO PARA SITUAÇÕES COMPLEXAS DIVERSAS
title RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
spellingShingle RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
Pinto Sousa, Pedro
Renal auto-transplant
Nutcracker syndrome
Renal artery aneurysm
Ex-vivo repair
laparoscopy
Autotransplante renal
laparoscopia
Síndrome de nutcracker
Aneurisma da artéria renal
Reparo ex vivo
title_short RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
title_full RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
title_fullStr RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
title_full_unstemmed RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
title_sort RENAL AUTOTRANSPLANTATION: A SOLUTION FOR DIFFERENT COMPLEX SITUATIONS
author Pinto Sousa, Pedro
author_facet Pinto Sousa, Pedro
Sá Pinto, Pedro
Machado, Rui
Almeida, Rui
author_role author
author2 Sá Pinto, Pedro
Machado, Rui
Almeida, Rui
author2_role author
author
author
dc.contributor.author.fl_str_mv Pinto Sousa, Pedro
Sá Pinto, Pedro
Machado, Rui
Almeida, Rui
dc.subject.por.fl_str_mv Renal auto-transplant
Nutcracker syndrome
Renal artery aneurysm
Ex-vivo repair
laparoscopy
Autotransplante renal
laparoscopia
Síndrome de nutcracker
Aneurisma da artéria renal
Reparo ex vivo
topic Renal auto-transplant
Nutcracker syndrome
Renal artery aneurysm
Ex-vivo repair
laparoscopy
Autotransplante renal
laparoscopia
Síndrome de nutcracker
Aneurisma da artéria renal
Reparo ex vivo
description Introduction: Renal autotransplantation (RA) is a safe and effective procedure to reconstruct the urinary tract which first successful surgery was performed by Hardy in 1963. The main indications reported to perform a RA generally include renovascular disease, ureteral pathologies and neoplastic disease. Furthermore, RA may be useful as an ultimate recourse in preventing kidney loss in highly selected patients, especially when conventional methods have failed. Materials and Methods: The authors describe four total different situations where the RA was the key solution for the pathology initially presented. Clinical case I – A 52 years old male with a previous history of left nephrectomy due to a preceding exacerbation of his basal Crohn's disease and also a right ureter cutaneostomie, presented now with repetitive urinary tract infections that led to renal function impairment; Clinical case II – A 57 years old female with the diagnosis of renal artery aneurysm while being studied as a potential kidney donor; Clinical case III – A 49 years old male admitted in the emergency room after a penetrating trauma which conditioned bowel and ureteral lesions with postoperative consecutive and recurrent peritoneal infections that compounded a necessity for a left ureterostomy, that the patient vehemently refused; Clinical case IV – A 24 years old female with the diagnosis of Nutcracker syndrome identified after being studied regarding repetitive urgency admissions with frank haematuria. Results: Every patient was submitted to laparoscopic nephrectomy, ex-vivo reconstruction, if necessary, and kidney transplantation to the iliac fossa. The interventions were uneventful and only one patient faced a minor post-operative complication (surgical wound dehiscende). We performed an ultrasound and renal scintigraphy evaluation on following days after each procedure to attest normal renal perfusion. Discussion: The RA were conducted in two patients with ureteral cutaneostomie because there was no viable alternative but kidney loss. The other two clinical cases were treated with RA because they concerned a complex renovascular disease (one arterial and the other venous). Despite the existence of an endovascular option for these patients, long term follow-up studies are still lacking. Conclusion: The RA is a viable option in specific situations for kidney salvage. The recent development of laparoscopic nephrectomy significantly decreased the surgical hostility to the patient and promoted the RA as a value option for the treatment of complex vascular pathologies, traumatic disease and specific medical situations. It represents a credible alternative with attested results already described in the literature thus requiring a vast Institutional experience withconventional renal transplantation.  
publishDate 2022
dc.date.none.fl_str_mv 2022-03-02T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.172
oai:ojs.acvjournal.com:article/172
url https://doi.org/10.48750/acv.172
identifier_str_mv oai:ojs.acvjournal.com:article/172
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/172
https://doi.org/10.48750/acv.172
http://acvjournal.com/index.php/acv/article/view/172/277
dc.rights.driver.fl_str_mv Copyright (c) 2022 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 17 No. 4 (2021): December; 339-343
Angiologia e Cirurgia Vascular; Vol. 17 N.º 4 (2021): Dezembro; 339-343
2183-0096
1646-706X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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