Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family

Detalhes bibliográficos
Autor(a) principal: Tanaka, Kohtaro
Data de Publicação: 2015
Outros Autores: Diekmann, Yoan, Hazbun, Alexis, Hijazi, Assia, Vreede, Barbara, Roch, Fernando, Sucena, Élio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/786
Resumo: The deposited article version is a "MBE Advance Access" published on March 4, 2015" provided by Oxford University Press, and it contains attached the supplementary materials within the pdf.
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spelling Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene FamilyAnimalsEmbryo, NonmammalianEvolution, MolecularGene DuplicationGene Expression ProfilingInsectsOrgan SpecificityPhylogenySpecies SpecificityGene Expression RegulationGenes, InsectMultigene FamilyThe deposited article version is a "MBE Advance Access" published on March 4, 2015" provided by Oxford University Press, and it contains attached the supplementary materials within the pdf.The deposited article is a post-print version.Some supplementary materials are not present in the uploaded version of the article.Gene families often consist of members with diverse expression domains reflecting their functions in a wide variety of tissues. However, how the expression of individual members, and thus their tissue-specific functions, diversified during the course of gene family expansion is not well understood. In this study, we approached this question through the analysis of the duplication history and transcriptional evolution of a rapidly expanding subfamily of insect Ly6 genes. We analyzed different insect genomes and identified seven Ly6 genes that have originated from a single ancestor through sequential duplication within the higher Diptera. We then determined how the original embryonic expression pattern of the founding gene diversified by characterizing its tissue-specific expression in the beetle Tribolium castaneum, the butterfly Bicyclus anynana, and the mosquito Anopheles stephensi and those of its duplicates in three higher dipteran species, representing various stages of the duplication history (Megaselia abdita, Ceratitis capitata, and Drosophila melanogaster). Our results revealed that frequent neofunctionalization episodes contributed to the increased expression breadth of this subfamily and that these events occurred after duplication and speciation events at comparable frequencies. In addition, at each duplication node, we consistently found asymmetric expression divergence. One paralog inherited most of the tissue-specificities of the founder gene, whereas the other paralog evolved drastically reduced expression domains. Our approach attests to the power of combining a well-established duplication history with a comprehensive coverage of representative species in acquiring unequivocal information about the dynamics of gene expression evolution in gene families.IAEA Seibersdorf (Austria); USDA; Duke University; McGill University; DRGC (Kyoto); DSHB (Iowa); Toulouse RIO Imaging Platform; Fundação para a Ciência e a Tecnologia grants: (SFRH/BPD/75139/2010, ANR-13-ISV7-0001-01, ANR-13-ISV7-0001-02, FCT-ANR/BIA-ANM/0003/2013); Fundação Calouste Gulbenkian; Instituto Gulbenkian de Ciência; Agence Nationale de la Recherche (ANR).Oxford University PressARCATanaka, KohtaroDiekmann, YoanHazbun, AlexisHijazi, AssiaVreede, BarbaraRoch, FernandoSucena, Élio2017-09-14T15:25:29Z2015-03-042015-03-04T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/786engKohtaro Tanaka, Yoan Diekmann, Alexis Hazbun, Assia Hijazi, Barbara Vreede, Fernando Roch, Élio Sucena; Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family, Molecular Biology and Evolution, Volume 32, Issue 7, 1 July 2015, Pages 1730–1747, https://doi.org/10.1093/molbev/msv05210.1093/molbev/msv052info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:11Zoai:arca.igc.gulbenkian.pt:10400.7/786Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:12:00.729605Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
title Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
spellingShingle Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
Tanaka, Kohtaro
Animals
Embryo, Nonmammalian
Evolution, Molecular
Gene Duplication
Gene Expression Profiling
Insects
Organ Specificity
Phylogeny
Species Specificity
Gene Expression Regulation
Genes, Insect
Multigene Family
title_short Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
title_full Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
title_fullStr Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
title_full_unstemmed Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
title_sort Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family
author Tanaka, Kohtaro
author_facet Tanaka, Kohtaro
Diekmann, Yoan
Hazbun, Alexis
Hijazi, Assia
Vreede, Barbara
Roch, Fernando
Sucena, Élio
author_role author
author2 Diekmann, Yoan
Hazbun, Alexis
Hijazi, Assia
Vreede, Barbara
Roch, Fernando
Sucena, Élio
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Tanaka, Kohtaro
Diekmann, Yoan
Hazbun, Alexis
Hijazi, Assia
Vreede, Barbara
Roch, Fernando
Sucena, Élio
dc.subject.por.fl_str_mv Animals
Embryo, Nonmammalian
Evolution, Molecular
Gene Duplication
Gene Expression Profiling
Insects
Organ Specificity
Phylogeny
Species Specificity
Gene Expression Regulation
Genes, Insect
Multigene Family
topic Animals
Embryo, Nonmammalian
Evolution, Molecular
Gene Duplication
Gene Expression Profiling
Insects
Organ Specificity
Phylogeny
Species Specificity
Gene Expression Regulation
Genes, Insect
Multigene Family
description The deposited article version is a "MBE Advance Access" published on March 4, 2015" provided by Oxford University Press, and it contains attached the supplementary materials within the pdf.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-04
2015-03-04T00:00:00Z
2017-09-14T15:25:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/786
url http://hdl.handle.net/10400.7/786
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Kohtaro Tanaka, Yoan Diekmann, Alexis Hazbun, Assia Hijazi, Barbara Vreede, Fernando Roch, Élio Sucena; Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family, Molecular Biology and Evolution, Volume 32, Issue 7, 1 July 2015, Pages 1730–1747, https://doi.org/10.1093/molbev/msv052
10.1093/molbev/msv052
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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