Bacteriophages as a tool to tackle Alzheimer´s Disease
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/77007 |
Resumo: | Invited Lecture. |
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Bacteriophages as a tool to tackle Alzheimer´s DiseaseInvited Lecture.Amyloid-beta (AB) is a prime suspect to cause Alzheimers disease (AD), an irreversible, progressive and age-dependent neurodegenerative disorder affecting millions of people worldwide. An accumulation of AB in the brain leads to its aggregation into soluble oligomeric and fibrillar clusters, which are the culprits to impair synaptic function and memory formation in mice models. Currently, we lack diagnostic tools to detect AB oligomers/fibrils in the brain, and the ones used provide a late diagnosis. In order to overcome the blood-brain-barrier (BBB), we used bacteriophages (phages) and phage display technology, to develop a phage-based tool for AD early diagnosis. In this seminar an overview of this work and the latest results will be presented.info:eu-repo/semantics/publishedVersionUniversidade do MinhoMartins, Ivone M.2021-05-032021-05-03T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectapplication/pdfhttp://hdl.handle.net/1822/77007engMartins, Ivone M., Invited Lecture: Bacteriophages as a tool to tackle Alzheimer´s Disease. SILS - CNS Seminars, Amsterdam, The Netherlands, 2021.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:19:29Zoai:repositorium.sdum.uminho.pt:1822/77007Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:12:26.135913Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
title |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
spellingShingle |
Bacteriophages as a tool to tackle Alzheimer´s Disease Martins, Ivone M. |
title_short |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
title_full |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
title_fullStr |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
title_full_unstemmed |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
title_sort |
Bacteriophages as a tool to tackle Alzheimer´s Disease |
author |
Martins, Ivone M. |
author_facet |
Martins, Ivone M. |
author_role |
author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Martins, Ivone M. |
description |
Invited Lecture. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-03 2021-05-03T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/77007 |
url |
http://hdl.handle.net/1822/77007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Martins, Ivone M., Invited Lecture: Bacteriophages as a tool to tackle Alzheimer´s Disease. SILS - CNS Seminars, Amsterdam, The Netherlands, 2021. |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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