Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries

Detalhes bibliográficos
Autor(a) principal: Fronteira, Inês
Data de Publicação: 2022
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25761/anaisihmt.429
Resumo: Introduction: Some vaccines seem to have effects beyond those of targeted diseases. These are called non-specific effects. Objective: To identify the studies conducted in PALOP on non-specific effects of human vaccines and summarize their main findings. Methods: Rapid review of experimental, cohort, case-control and cross-sectional studies indexed in Pubmed, Scopus or LILACS on i) non-specific effects of vaccines in ii) human populations from iii) Angola, Cape Verde, Guinea-Bissau, Equatorial Guinea, Mozambique and/or São Tomé and Príncipe. Qualitative synthesis of results. Results: 421 studies retrieved; data collected on 67. 66 of these were conducted in Guinea-Bissau, were mainly cohort and experimental studies and most commonly included measles vaccine, BCG, DTP and OPV. The non-specific effects studied included mostly mortality and morbidity. Discussion: Non-specific effects of vaccines are a relevant issue for global public health.
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spelling Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African CountriesLes effets non spécifiques des vaccines : une révision rapide des études réalisés aux pays africaines de langue officiel portugaiseEfeitos não específicos das vacinas: revisão rápida dos estudos realizados nos países africanos de língua oficial portuguesaIntroduction: Some vaccines seem to have effects beyond those of targeted diseases. These are called non-specific effects. Objective: To identify the studies conducted in PALOP on non-specific effects of human vaccines and summarize their main findings. Methods: Rapid review of experimental, cohort, case-control and cross-sectional studies indexed in Pubmed, Scopus or LILACS on i) non-specific effects of vaccines in ii) human populations from iii) Angola, Cape Verde, Guinea-Bissau, Equatorial Guinea, Mozambique and/or São Tomé and Príncipe. Qualitative synthesis of results. Results: 421 studies retrieved; data collected on 67. 66 of these were conducted in Guinea-Bissau, were mainly cohort and experimental studies and most commonly included measles vaccine, BCG, DTP and OPV. The non-specific effects studied included mostly mortality and morbidity. Discussion: Non-specific effects of vaccines are a relevant issue for global public health.Introduction: Certains vaccins semblent avoir des effets autres que ceux sur les maladies pour lesquelles ils ont été conçus, appelés effets non spécifiques. Objectif: Identifier les études menées dans le cadre du PALOP sur les effets non spécifiques des vaccins humains et résumer leurs principaux résultats. Méthodes: Revue rapide des études expérimentales, de cohorte, cas-témoins et transversales indexées dans Pubmed, Scopus ou LILACS sur i) les effets non spécifiques des vaccins dans ii) les populations humaines de iii) l'Angola, le Cap-Vert, la Guinée-Bissau, la Guinée équatoriale, le Mozambique et/ou São Tomé et Príncipe. Synthèse qualitative des résultats. Résultats: 421 études retrouvées, données ont été colligés sur 67. 66 des 67 études ont été menées en Guinée-Bissau, étaient principalement des études de cohorte et expérimentales et portaient le plus souvent sur le vaccin contre la rougeole, le BCG, le DTP et le VOP. Les effets non spécifiques étudiés comprenaient surtout la mortalité et la morbidité. Discussion: Les effets non spécifiques des vaccins sont une question importante pour la santé publique mondiale.Introdução: Algumas vacinas parecem ter também efeitos para além daqueles nas doenças para as quais foram desenhadas, denominados de efeitos não específicos. Objetivo: Identificar os estudos realizados nos PALOP sobre os efeitos não específicos das vacinas humanas e resumir os seus principais achados. Métodos: Revisão rápida de estudos experimentais, coorte, caso-controlo e transversais indexados na Pubmed, Scopus ou LILACS sobre os i) efeitos não específicos de vacinas em ii) populações humanas de iii) Angola, Cabo Verde, Guiné-Bissau, Guiné Equatorial, Moçambique e/ou São Tomé e Príncipe. Síntese qualitativa dos resultados.Resultados: 421 estudos recuperados, colhidos dados sobre 67. Destes, 66 foram realizados na Guiné-Bissau, eram prin- cipalmente estudos de coorte e experimentais e incluíam mais frequentemente a vacina do sarampo, BCG, DTP e VOP. Os efeitos não específicos estudados incluíam maioritariamente a mortalidade e a morbilidade. Discussão: Os efeitos não específicos das vacinas são um tema relevante para a saúde pública global.Universidade Nova de Lisboa2022-10-22info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25761/anaisihmt.429oai:ojs.anaisihmt.com:article/429Anais do Instituto de Higiene e Medicina Tropical; Vol 21 (2022): Estratégias de vacinação em contexto pandémico; 48-65Anais do Instituto de Higiene e Medicina Tropical; v. 21 (2022): Estratégias de vacinação em contexto pandémico; 48-652184-23100303-7762reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://anaisihmt.com/index.php/ihmt/article/view/429https://doi.org/10.25761/anaisihmt.429http://anaisihmt.com/index.php/ihmt/article/view/429/354http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFronteira, Inês2022-10-26T05:45:20Zoai:ojs.anaisihmt.com:article/429Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:14:03.096247Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
Les effets non spécifiques des vaccines : une révision rapide des études réalisés aux pays africaines de langue officiel portugaise
Efeitos não específicos das vacinas: revisão rápida dos estudos realizados nos países africanos de língua oficial portuguesa
title Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
spellingShingle Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
Fronteira, Inês
title_short Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
title_full Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
title_fullStr Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
title_full_unstemmed Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
title_sort Non-specific effects of vaccines: a rapid review of studies conducted in Portuguese Speaking African Countries
author Fronteira, Inês
author_facet Fronteira, Inês
author_role author
dc.contributor.author.fl_str_mv Fronteira, Inês
description Introduction: Some vaccines seem to have effects beyond those of targeted diseases. These are called non-specific effects. Objective: To identify the studies conducted in PALOP on non-specific effects of human vaccines and summarize their main findings. Methods: Rapid review of experimental, cohort, case-control and cross-sectional studies indexed in Pubmed, Scopus or LILACS on i) non-specific effects of vaccines in ii) human populations from iii) Angola, Cape Verde, Guinea-Bissau, Equatorial Guinea, Mozambique and/or São Tomé and Príncipe. Qualitative synthesis of results. Results: 421 studies retrieved; data collected on 67. 66 of these were conducted in Guinea-Bissau, were mainly cohort and experimental studies and most commonly included measles vaccine, BCG, DTP and OPV. The non-specific effects studied included mostly mortality and morbidity. Discussion: Non-specific effects of vaccines are a relevant issue for global public health.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-22
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25761/anaisihmt.429
oai:ojs.anaisihmt.com:article/429
url https://doi.org/10.25761/anaisihmt.429
identifier_str_mv oai:ojs.anaisihmt.com:article/429
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://anaisihmt.com/index.php/ihmt/article/view/429
https://doi.org/10.25761/anaisihmt.429
http://anaisihmt.com/index.php/ihmt/article/view/429/354
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nova de Lisboa
publisher.none.fl_str_mv Universidade Nova de Lisboa
dc.source.none.fl_str_mv Anais do Instituto de Higiene e Medicina Tropical; Vol 21 (2022): Estratégias de vacinação em contexto pandémico; 48-65
Anais do Instituto de Higiene e Medicina Tropical; v. 21 (2022): Estratégias de vacinação em contexto pandémico; 48-65
2184-2310
0303-7762
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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