A ensemble methodology for automatic classification of chest X-rays using deep learning

Detalhes bibliográficos
Autor(a) principal: Luis Vogado
Data de Publicação: 2022
Outros Autores: Flávio Araújo, Pedro Santos Neto, João Almeida, João Manuel R. S. Tavares, Rodrigo Veras
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/140809
Resumo: Chest radiographies, or chest X-rays, are the most standard imaging exams used in daily hospitals. Responsible for assisting in detecting numerous pathologies and findings that directly interfere in the patient's life, this exam is therefore crucial in screening patients. This work proposes a methodology based on a Convolutional Neural Networks (CNNs) ensemble to aid the diagnosis of chest X-ray exams by screening them with a high probability of being normal or abnormal. In the development of this study, a private dataset with frontal and lateral projections X-ray images was used. To build the ensemble model, VGG-16, ResNet50 and DenseNet121 architectures, which are commonly used in the classification of Chest X-rays, were evaluated. A Confidence Threshold (CTR) was used to define the predictions into High Confidence Normal (HCn), Borderline classification (BC), or High Confidence Abnormal (HCa). In the tests performed, very promising results were achieved: 54.63% of the exams were classified with high confidence; of the normal exams, 32% were classified as HCn with an false discovery rate (FDR) of 1.68%; and as to the abnormal exams, 23% were classified as HCa with 4.91% false omission rate (FOR).
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spelling A ensemble methodology for automatic classification of chest X-rays using deep learningCiências Tecnológicas, Ciências médicas e da saúdeTechnological sciences, Medical and Health sciencesChest radiographies, or chest X-rays, are the most standard imaging exams used in daily hospitals. Responsible for assisting in detecting numerous pathologies and findings that directly interfere in the patient's life, this exam is therefore crucial in screening patients. This work proposes a methodology based on a Convolutional Neural Networks (CNNs) ensemble to aid the diagnosis of chest X-ray exams by screening them with a high probability of being normal or abnormal. In the development of this study, a private dataset with frontal and lateral projections X-ray images was used. To build the ensemble model, VGG-16, ResNet50 and DenseNet121 architectures, which are commonly used in the classification of Chest X-rays, were evaluated. A Confidence Threshold (CTR) was used to define the predictions into High Confidence Normal (HCn), Borderline classification (BC), or High Confidence Abnormal (HCa). In the tests performed, very promising results were achieved: 54.63% of the exams were classified with high confidence; of the normal exams, 32% were classified as HCn with an false discovery rate (FDR) of 1.68%; and as to the abnormal exams, 23% were classified as HCa with 4.91% false omission rate (FOR).2022-062022-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleimage/pngapplication/pdfhttps://hdl.handle.net/10216/140809eng0010-482510.1016/j.compbiomed.2022.105442Luis VogadoFlávio AraújoPedro Santos NetoJoão AlmeidaJoão Manuel R. S. TavaresRodrigo Verasinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:22:53Zoai:repositorio-aberto.up.pt:10216/140809Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:00:00.619409Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A ensemble methodology for automatic classification of chest X-rays using deep learning
title A ensemble methodology for automatic classification of chest X-rays using deep learning
spellingShingle A ensemble methodology for automatic classification of chest X-rays using deep learning
Luis Vogado
Ciências Tecnológicas, Ciências médicas e da saúde
Technological sciences, Medical and Health sciences
title_short A ensemble methodology for automatic classification of chest X-rays using deep learning
title_full A ensemble methodology for automatic classification of chest X-rays using deep learning
title_fullStr A ensemble methodology for automatic classification of chest X-rays using deep learning
title_full_unstemmed A ensemble methodology for automatic classification of chest X-rays using deep learning
title_sort A ensemble methodology for automatic classification of chest X-rays using deep learning
author Luis Vogado
author_facet Luis Vogado
Flávio Araújo
Pedro Santos Neto
João Almeida
João Manuel R. S. Tavares
Rodrigo Veras
author_role author
author2 Flávio Araújo
Pedro Santos Neto
João Almeida
João Manuel R. S. Tavares
Rodrigo Veras
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Luis Vogado
Flávio Araújo
Pedro Santos Neto
João Almeida
João Manuel R. S. Tavares
Rodrigo Veras
dc.subject.por.fl_str_mv Ciências Tecnológicas, Ciências médicas e da saúde
Technological sciences, Medical and Health sciences
topic Ciências Tecnológicas, Ciências médicas e da saúde
Technological sciences, Medical and Health sciences
description Chest radiographies, or chest X-rays, are the most standard imaging exams used in daily hospitals. Responsible for assisting in detecting numerous pathologies and findings that directly interfere in the patient's life, this exam is therefore crucial in screening patients. This work proposes a methodology based on a Convolutional Neural Networks (CNNs) ensemble to aid the diagnosis of chest X-ray exams by screening them with a high probability of being normal or abnormal. In the development of this study, a private dataset with frontal and lateral projections X-ray images was used. To build the ensemble model, VGG-16, ResNet50 and DenseNet121 architectures, which are commonly used in the classification of Chest X-rays, were evaluated. A Confidence Threshold (CTR) was used to define the predictions into High Confidence Normal (HCn), Borderline classification (BC), or High Confidence Abnormal (HCa). In the tests performed, very promising results were achieved: 54.63% of the exams were classified with high confidence; of the normal exams, 32% were classified as HCn with an false discovery rate (FDR) of 1.68%; and as to the abnormal exams, 23% were classified as HCa with 4.91% false omission rate (FOR).
publishDate 2022
dc.date.none.fl_str_mv 2022-06
2022-06-01T00:00:00Z
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dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/140809
url https://hdl.handle.net/10216/140809
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0010-4825
10.1016/j.compbiomed.2022.105442
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