Prognostic factors after liver resection for colorectal liver metastasis

Detalhes bibliográficos
Autor(a) principal: Matias, Margarida
Data de Publicação: 2015
Outros Autores: Casa-Nova, Mafalda, Faria, Mariana, Pires, Ricardo, Tato-Costa, Joana, Ribeiro, Maria Leonor, Costa, Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54636
Resumo: © Ordem dos Médicos 2015
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spelling Prognostic factors after liver resection for colorectal liver metastasisFactores de prognóstico após ressecção de metástases hepáticas de cancro colo-rectalColorectal NeoplasmsHepatectomyLiver neoplasms/secondaryLiver neoplasms/surgeryPrognosis© Ordem dos Médicos 2015Introduction: Surgery is the only potentially curative treatment for patients with colorectal liver metastases, resulting in 5-year survival rates of 36 - 58. Although many studies have been performed to determine prognostic factors for tumor recurrence and survival after resection of colorectal liver metastases, there are few prognostic scoring systems stratifying patients undergoing surgery for colorectal liver metastases into risk group models. Objectives: To identify, evaluate and compare the existing prognostic scores for survival after surgery for resection of colorectal liver metastases. Material and methods: Electronic search in PubMed, Cochrane and Embase from 1990 to 2013 using the terms ' hepatic resection', ' colorectal cancer' , 'liver metastasis', ' hepatectomy', ' prognostic' , and ' score' . Only studies proposing a prognostic model or risk stratification based on clinical and/or pathological variables were included. Results: From 1996 to June 2013, 19 scoring systems were identified, including one nomogram. Thirty prognostic factors were identified although none of the factors was common to all prognostic models. The 4 factors most often included were: number of liver metastases, regional lymph node metastization of primary tumor, preoperative CEA level and maximum size of metastases. The median study sample size was 305 patients (81-1 568 patients) and median follow-up was 33 months (16-54 months). All studies were retrospective and used the Cox proportional hazards model for multi-variable analysis. Conclusion: Several factors have been constantly reported as having prognostic value after liver resection of colorectal livermetastases, although there is no consensus on the ideal scoring system.Ordem dos MédicosRepositório da Universidade de LisboaMatias, MargaridaCasa-Nova, MafaldaFaria, MarianaPires, RicardoTato-Costa, JoanaRibeiro, Maria LeonorCosta, Luis2022-09-29T16:12:56Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54636engActa Med Port. 2015 May-Jun;28(3):357-3690870-399X10.20344/amp.48161646-0758info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:01:08Zoai:repositorio.ul.pt:10451/54636Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:05:25.706058Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Prognostic factors after liver resection for colorectal liver metastasis
Factores de prognóstico após ressecção de metástases hepáticas de cancro colo-rectal
title Prognostic factors after liver resection for colorectal liver metastasis
spellingShingle Prognostic factors after liver resection for colorectal liver metastasis
Matias, Margarida
Colorectal Neoplasms
Hepatectomy
Liver neoplasms/secondary
Liver neoplasms/surgery
Prognosis
title_short Prognostic factors after liver resection for colorectal liver metastasis
title_full Prognostic factors after liver resection for colorectal liver metastasis
title_fullStr Prognostic factors after liver resection for colorectal liver metastasis
title_full_unstemmed Prognostic factors after liver resection for colorectal liver metastasis
title_sort Prognostic factors after liver resection for colorectal liver metastasis
author Matias, Margarida
author_facet Matias, Margarida
Casa-Nova, Mafalda
Faria, Mariana
Pires, Ricardo
Tato-Costa, Joana
Ribeiro, Maria Leonor
Costa, Luis
author_role author
author2 Casa-Nova, Mafalda
Faria, Mariana
Pires, Ricardo
Tato-Costa, Joana
Ribeiro, Maria Leonor
Costa, Luis
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Matias, Margarida
Casa-Nova, Mafalda
Faria, Mariana
Pires, Ricardo
Tato-Costa, Joana
Ribeiro, Maria Leonor
Costa, Luis
dc.subject.por.fl_str_mv Colorectal Neoplasms
Hepatectomy
Liver neoplasms/secondary
Liver neoplasms/surgery
Prognosis
topic Colorectal Neoplasms
Hepatectomy
Liver neoplasms/secondary
Liver neoplasms/surgery
Prognosis
description © Ordem dos Médicos 2015
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2022-09-29T16:12:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54636
url http://hdl.handle.net/10451/54636
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Med Port. 2015 May-Jun;28(3):357-369
0870-399X
10.20344/amp.4816
1646-0758
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
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