When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use

Detalhes bibliográficos
Autor(a) principal: Machado Nogueira, J
Data de Publicação: 2021
Outros Autores: Freire, MJ, Vila Nova, V, Jesus, G
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/3924
Resumo: Tacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior psychiatric history, who developed a severe psychosis secondary to supratherapeutic tacrolimus' blood concentrations. This case highlights the importance of clinical awareness to rare but severe neuropsychiatric effects due to tacrolimus use.
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spelling When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus UseCHLC PSIQPsychosisTacrolimusNeurotoxicNeuropsychiatric Side EffectsTacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior psychiatric history, who developed a severe psychosis secondary to supratherapeutic tacrolimus' blood concentrations. This case highlights the importance of clinical awareness to rare but severe neuropsychiatric effects due to tacrolimus use.KargerRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMachado Nogueira, JFreire, MJVila Nova, VJesus, G2021-11-24T15:49:08Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3924engCase Rep Nephrol Dial. 2021 Aug 4;11(2):241-246.10.1159/000515048.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:44:38Zoai:repositorio.chlc.min-saude.pt:10400.17/3924Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:21:13.973491Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
title When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
spellingShingle When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
Machado Nogueira, J
CHLC PSIQ
Psychosis
Tacrolimus
Neurotoxic
Neuropsychiatric Side Effects
title_short When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
title_full When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
title_fullStr When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
title_full_unstemmed When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
title_sort When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use
author Machado Nogueira, J
author_facet Machado Nogueira, J
Freire, MJ
Vila Nova, V
Jesus, G
author_role author
author2 Freire, MJ
Vila Nova, V
Jesus, G
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Machado Nogueira, J
Freire, MJ
Vila Nova, V
Jesus, G
dc.subject.por.fl_str_mv CHLC PSIQ
Psychosis
Tacrolimus
Neurotoxic
Neuropsychiatric Side Effects
topic CHLC PSIQ
Psychosis
Tacrolimus
Neurotoxic
Neuropsychiatric Side Effects
description Tacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior psychiatric history, who developed a severe psychosis secondary to supratherapeutic tacrolimus' blood concentrations. This case highlights the importance of clinical awareness to rare but severe neuropsychiatric effects due to tacrolimus use.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-24T15:49:08Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/3924
url http://hdl.handle.net/10400.17/3924
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Case Rep Nephrol Dial. 2021 Aug 4;11(2):241-246.
10.1159/000515048.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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