Bioanalytical approach-ageing, exercise and oxidative stress
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/35835 |
Resumo: | Abstract: Exercise interferes with the ageing, causing changes in markers of the antioxidant system, such as nitric oxide (NO) and uric acid. Aim: The objective of this study was to evaluate if regular exercise affects the ageing process by causing changes in the antioxidant markers, nitric oxide and uric acid, in individuals aged ≥ 65 years, subjected to an exercise plan. Methods: The study involved 12 participants distributed in an experimental and control group. The experimental group performed exercises guided by a physiotherapist during 12 weeks. Three blood samples were collected from participants: T0, at the start of the study; T1, after 12 weeks of exercise and T2, 12 weeks after finishing the exercise. NO and uric acid were quantified with commercial kits. The statistics were performed using SPSS and the ANOVA and Student t-tests were applied. Result: In the experimental group, the mean values of NO showed an increase between T0 and T1, with a slight decrease between T1 and T2. Similar effects were observed for the uric acid concentration in the experimental group, with statistical significance from T0 to T1. Conclusion: After exercise, there was an increase in blood uric acid and NO levels, highlighting the importance of moderate and controlled exercise practice. Therefore, exercise seems relevant and beneficial in activating antioxidant mechanisms. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Bioanalytical approach-ageing, exercise and oxidative stressAgeingExerciseNitric oxideUric acidAgeing processSignalling pathwayPostponementBiological processEnvelhecimentoExercício físicoÓxido nítricoÁcido úricoProcessos biológicosAbstract: Exercise interferes with the ageing, causing changes in markers of the antioxidant system, such as nitric oxide (NO) and uric acid. Aim: The objective of this study was to evaluate if regular exercise affects the ageing process by causing changes in the antioxidant markers, nitric oxide and uric acid, in individuals aged ≥ 65 years, subjected to an exercise plan. Methods: The study involved 12 participants distributed in an experimental and control group. The experimental group performed exercises guided by a physiotherapist during 12 weeks. Three blood samples were collected from participants: T0, at the start of the study; T1, after 12 weeks of exercise and T2, 12 weeks after finishing the exercise. NO and uric acid were quantified with commercial kits. The statistics were performed using SPSS and the ANOVA and Student t-tests were applied. Result: In the experimental group, the mean values of NO showed an increase between T0 and T1, with a slight decrease between T1 and T2. Similar effects were observed for the uric acid concentration in the experimental group, with statistical significance from T0 to T1. Conclusion: After exercise, there was an increase in blood uric acid and NO levels, highlighting the importance of moderate and controlled exercise practice. Therefore, exercise seems relevant and beneficial in activating antioxidant mechanisms.Juniper publishersRepositório ComumValado, AnaLopes, DianaOsório, NádiaCaseiro, ArmandoFigueiredo, JoãoPatrício, CristinaPacheco, Maria PaulaOostingh, Gertie JannekeGabriel, António José dos Santos2021-03-05T20:54:15Z2020-05-27T00:00:00Z2020-05-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/35835eng2572-123210.19080/JCMAH.2020.11.555810info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T15:41:21Zoai:comum.rcaap.pt:10400.26/35835Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:17:05.731274Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Bioanalytical approach-ageing, exercise and oxidative stress |
title |
Bioanalytical approach-ageing, exercise and oxidative stress |
spellingShingle |
Bioanalytical approach-ageing, exercise and oxidative stress Valado, Ana Ageing Exercise Nitric oxide Uric acid Ageing process Signalling pathway Postponement Biological process Envelhecimento Exercício físico Óxido nítrico Ácido úrico Processos biológicos |
title_short |
Bioanalytical approach-ageing, exercise and oxidative stress |
title_full |
Bioanalytical approach-ageing, exercise and oxidative stress |
title_fullStr |
Bioanalytical approach-ageing, exercise and oxidative stress |
title_full_unstemmed |
Bioanalytical approach-ageing, exercise and oxidative stress |
title_sort |
Bioanalytical approach-ageing, exercise and oxidative stress |
author |
Valado, Ana |
author_facet |
Valado, Ana Lopes, Diana Osório, Nádia Caseiro, Armando Figueiredo, João Patrício, Cristina Pacheco, Maria Paula Oostingh, Gertie Janneke Gabriel, António José dos Santos |
author_role |
author |
author2 |
Lopes, Diana Osório, Nádia Caseiro, Armando Figueiredo, João Patrício, Cristina Pacheco, Maria Paula Oostingh, Gertie Janneke Gabriel, António José dos Santos |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Valado, Ana Lopes, Diana Osório, Nádia Caseiro, Armando Figueiredo, João Patrício, Cristina Pacheco, Maria Paula Oostingh, Gertie Janneke Gabriel, António José dos Santos |
dc.subject.por.fl_str_mv |
Ageing Exercise Nitric oxide Uric acid Ageing process Signalling pathway Postponement Biological process Envelhecimento Exercício físico Óxido nítrico Ácido úrico Processos biológicos |
topic |
Ageing Exercise Nitric oxide Uric acid Ageing process Signalling pathway Postponement Biological process Envelhecimento Exercício físico Óxido nítrico Ácido úrico Processos biológicos |
description |
Abstract: Exercise interferes with the ageing, causing changes in markers of the antioxidant system, such as nitric oxide (NO) and uric acid. Aim: The objective of this study was to evaluate if regular exercise affects the ageing process by causing changes in the antioxidant markers, nitric oxide and uric acid, in individuals aged ≥ 65 years, subjected to an exercise plan. Methods: The study involved 12 participants distributed in an experimental and control group. The experimental group performed exercises guided by a physiotherapist during 12 weeks. Three blood samples were collected from participants: T0, at the start of the study; T1, after 12 weeks of exercise and T2, 12 weeks after finishing the exercise. NO and uric acid were quantified with commercial kits. The statistics were performed using SPSS and the ANOVA and Student t-tests were applied. Result: In the experimental group, the mean values of NO showed an increase between T0 and T1, with a slight decrease between T1 and T2. Similar effects were observed for the uric acid concentration in the experimental group, with statistical significance from T0 to T1. Conclusion: After exercise, there was an increase in blood uric acid and NO levels, highlighting the importance of moderate and controlled exercise practice. Therefore, exercise seems relevant and beneficial in activating antioxidant mechanisms. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05-27T00:00:00Z 2020-05-27T00:00:00Z 2021-03-05T20:54:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/35835 |
url |
http://hdl.handle.net/10400.26/35835 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2572-1232 10.19080/JCMAH.2020.11.555810 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Juniper publishers |
publisher.none.fl_str_mv |
Juniper publishers |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130033917263872 |