Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.4/321 |
Resumo: | OBJECTIVES: Although several algorithms have been proposed to select postmenopausal women PMW for dual-energy x-ray absorptiometry DEXA measurements information on their utility in clinical practice is scarce. Our aim was to assess the utility and the economic repercussion of the use of five of these algorithms in Portuguese postmenopausal women. METHODS: We included 588 PMW and selected five simple algorithms ORAI ABONE Body Weight Criterion OSTA and a modified version of OSTA (OST). Sensitivities specificities predictive values areas under the receiver operating characteristic curve (AUROC) and economic estimates were computed. RESULTS: Sensitivities ranged between 71.2%-80.8% and AUROC between 0.611-0.674. In PMW aged > or = 65 years (Y) the use of any of the algorithms would cause extra costs or a residual saving. In PMW aged > or = 55 and < 65Y considering total savings ABONE had the best performance but considering savings per preventable fracture, ORAI assumed the lead, followed by BWC. In the age group > or = 40 and < 55Y, the most profitable option considering total savings would be not doing DEXA to anyone; considering savings per preventable fracture, BWC figures as the most useful. CONCLUSIONS: This study provides evidence for the validity of all the selected tools as useful algorithms to select PMW for DEXA. On the basis of our results and considering the importance of simplicity in the applicability of an algorithm we would suggest the following strategy in Portuguese PMW: 1) Aged > or = 65Y: perform DEXA irrespective of other risk factors. 2) Aged < 65Y: perform DEXA if body weight < 70Kg. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesasPerformance of decision algorithms for the identification of low bone mineral density in portuguese postmenopausal womenDensidade ÓsseaOsteoporoseAlgoritmosOBJECTIVES: Although several algorithms have been proposed to select postmenopausal women PMW for dual-energy x-ray absorptiometry DEXA measurements information on their utility in clinical practice is scarce. Our aim was to assess the utility and the economic repercussion of the use of five of these algorithms in Portuguese postmenopausal women. METHODS: We included 588 PMW and selected five simple algorithms ORAI ABONE Body Weight Criterion OSTA and a modified version of OSTA (OST). Sensitivities specificities predictive values areas under the receiver operating characteristic curve (AUROC) and economic estimates were computed. RESULTS: Sensitivities ranged between 71.2%-80.8% and AUROC between 0.611-0.674. In PMW aged > or = 65 years (Y) the use of any of the algorithms would cause extra costs or a residual saving. In PMW aged > or = 55 and < 65Y considering total savings ABONE had the best performance but considering savings per preventable fracture, ORAI assumed the lead, followed by BWC. In the age group > or = 40 and < 55Y, the most profitable option considering total savings would be not doing DEXA to anyone; considering savings per preventable fracture, BWC figures as the most useful. CONCLUSIONS: This study provides evidence for the validity of all the selected tools as useful algorithms to select PMW for DEXA. On the basis of our results and considering the importance of simplicity in the applicability of an algorithm we would suggest the following strategy in Portuguese PMW: 1) Aged > or = 65Y: perform DEXA irrespective of other risk factors. 2) Aged < 65Y: perform DEXA if body weight < 70Kg.Sociedade Portuguesa de ReumatologiaRIHUCMachado, PPereira da Silva, JA2008-12-11T14:51:42Z20082008-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/321porActa Reumatol Port. 2008 Jul-Sep;33(3):314-28info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:21:28Zoai:rihuc.huc.min-saude.pt:10400.4/321Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:07.757285Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas Performance of decision algorithms for the identification of low bone mineral density in portuguese postmenopausal women |
title |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
spellingShingle |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas Machado, P Densidade Óssea Osteoporose Algoritmos |
title_short |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
title_full |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
title_fullStr |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
title_full_unstemmed |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
title_sort |
Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas |
author |
Machado, P |
author_facet |
Machado, P Pereira da Silva, JA |
author_role |
author |
author2 |
Pereira da Silva, JA |
author2_role |
author |
dc.contributor.none.fl_str_mv |
RIHUC |
dc.contributor.author.fl_str_mv |
Machado, P Pereira da Silva, JA |
dc.subject.por.fl_str_mv |
Densidade Óssea Osteoporose Algoritmos |
topic |
Densidade Óssea Osteoporose Algoritmos |
description |
OBJECTIVES: Although several algorithms have been proposed to select postmenopausal women PMW for dual-energy x-ray absorptiometry DEXA measurements information on their utility in clinical practice is scarce. Our aim was to assess the utility and the economic repercussion of the use of five of these algorithms in Portuguese postmenopausal women. METHODS: We included 588 PMW and selected five simple algorithms ORAI ABONE Body Weight Criterion OSTA and a modified version of OSTA (OST). Sensitivities specificities predictive values areas under the receiver operating characteristic curve (AUROC) and economic estimates were computed. RESULTS: Sensitivities ranged between 71.2%-80.8% and AUROC between 0.611-0.674. In PMW aged > or = 65 years (Y) the use of any of the algorithms would cause extra costs or a residual saving. In PMW aged > or = 55 and < 65Y considering total savings ABONE had the best performance but considering savings per preventable fracture, ORAI assumed the lead, followed by BWC. In the age group > or = 40 and < 55Y, the most profitable option considering total savings would be not doing DEXA to anyone; considering savings per preventable fracture, BWC figures as the most useful. CONCLUSIONS: This study provides evidence for the validity of all the selected tools as useful algorithms to select PMW for DEXA. On the basis of our results and considering the importance of simplicity in the applicability of an algorithm we would suggest the following strategy in Portuguese PMW: 1) Aged > or = 65Y: perform DEXA irrespective of other risk factors. 2) Aged < 65Y: perform DEXA if body weight < 70Kg. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-11T14:51:42Z 2008 2008-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.4/321 |
url |
http://hdl.handle.net/10400.4/321 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Acta Reumatol Port. 2008 Jul-Sep;33(3):314-28 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Reumatologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Reumatologia |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131696178659328 |