Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering

Detalhes bibliográficos
Autor(a) principal: Lopes, João
Data de Publicação: 2019
Outros Autores: Fonseca, Rita, Viana, Tânia, Fernandes, Cristiana, Morouço, Pedro, Moura, Carla, Biscaia, Sara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.8/8334
Resumo: Acknowledgements: This work is supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the Project references: UID/Multi/04044/2013 and PAMI - ROTEIRO/0328/2013 (Nº022158). It is also funded by the projects insitu.Biomas (POCI-01-0247-FEDER-017771), and NEXT. parts (POCI-01-0247-FEDER-017963) from the Portuguese National Innovation Agency.
id RCAP_8a64d59810a64cbcc2434118770a004c
oai_identifier_str oai:iconline.ipleiria.pt:10400.8/8334
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue EngineeringHydrogelPhotoinitiatorPoly(ethylene glycol)-dimethacrylateMechanical propertiesFTIRAcknowledgements: This work is supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the Project references: UID/Multi/04044/2013 and PAMI - ROTEIRO/0328/2013 (Nº022158). It is also funded by the projects insitu.Biomas (POCI-01-0247-FEDER-017771), and NEXT. parts (POCI-01-0247-FEDER-017963) from the Portuguese National Innovation Agency.Tissue Engineering depends on broadly techniques to regenerate tissues and/or organ functions. To do so, tailored polymeric and/or hydrogel scaffolds may be used to ensure the appropriate regeneration. Hydrogels are suitable materials for constructing cell-laden matrices as they can be produced with incorporation of cells and rapidly cross-linked in situ through photopolymerisation reactions. Measurement of the polymerization degree, as well as resistance to compression and water retention are fundamental tests to evaluate the characteristics of hydrogels. In this work, free-radical polymerisation of poly(ethylene glycol)-dimethacrylate (PEGDMA) in UV light was assessed. Several hydrogels with different photoinitiator and water contents were produced to evaluate their influence on hydrogels behaviour. Experiments showed that variations on water and photoinitiator content induce changes in the physical and chemical behaviour of hydrogels. As it was found, water content prevents polymerisation to occur and reduces the mechanical properties of hydrogels weakening them. Furthermore, differences were found in varying water content from 15 to 30%, since this increase turned hydrogels more fragile and increase their stabilization time for water retention.Trans Tech PublicationsIC-OnlineLopes, JoãoFonseca, RitaViana, TâniaFernandes, CristianaMorouço, PedroMoura, CarlaBiscaia, Sara2023-04-05T14:07:23Z2019-04-092019-04-09T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/8334engLopes, J., Fonseca, R., Viana, T., Fernandes, C., Morouço, P., Moura, C., & Biscaia, S. (2019). Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering. Applied Mechanics and Materials, 890, 290–300. https://doi.org/10.4028/www.scientific.net/amm.890.290https://doi.org/10.4028/www.scientific.net/AMM.890.2901662-7482info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T15:56:58Zoai:iconline.ipleiria.pt:10400.8/8334Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:51:02.341111Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
title Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
spellingShingle Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
Lopes, João
Hydrogel
Photoinitiator
Poly(ethylene glycol)-dimethacrylate
Mechanical properties
FTIR
title_short Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
title_full Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
title_fullStr Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
title_full_unstemmed Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
title_sort Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering
author Lopes, João
author_facet Lopes, João
Fonseca, Rita
Viana, Tânia
Fernandes, Cristiana
Morouço, Pedro
Moura, Carla
Biscaia, Sara
author_role author
author2 Fonseca, Rita
Viana, Tânia
Fernandes, Cristiana
Morouço, Pedro
Moura, Carla
Biscaia, Sara
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv IC-Online
dc.contributor.author.fl_str_mv Lopes, João
Fonseca, Rita
Viana, Tânia
Fernandes, Cristiana
Morouço, Pedro
Moura, Carla
Biscaia, Sara
dc.subject.por.fl_str_mv Hydrogel
Photoinitiator
Poly(ethylene glycol)-dimethacrylate
Mechanical properties
FTIR
topic Hydrogel
Photoinitiator
Poly(ethylene glycol)-dimethacrylate
Mechanical properties
FTIR
description Acknowledgements: This work is supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the Project references: UID/Multi/04044/2013 and PAMI - ROTEIRO/0328/2013 (Nº022158). It is also funded by the projects insitu.Biomas (POCI-01-0247-FEDER-017771), and NEXT. parts (POCI-01-0247-FEDER-017963) from the Portuguese National Innovation Agency.
publishDate 2019
dc.date.none.fl_str_mv 2019-04-09
2019-04-09T00:00:00Z
2023-04-05T14:07:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.8/8334
url http://hdl.handle.net/10400.8/8334
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Lopes, J., Fonseca, R., Viana, T., Fernandes, C., Morouço, P., Moura, C., & Biscaia, S. (2019). Characterization of Biocompatible Poly(Ethylene Glycol)-Dimethacrylate Hydrogels for Tissue Engineering. Applied Mechanics and Materials, 890, 290–300. https://doi.org/10.4028/www.scientific.net/amm.890.290
https://doi.org/10.4028/www.scientific.net/AMM.890.290
1662-7482
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Trans Tech Publications
publisher.none.fl_str_mv Trans Tech Publications
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799137002251091968

Registros relacionados