Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola

Detalhes bibliográficos
Autor(a) principal: Yefimenko, Lesya
Data de Publicação: 2023
Outros Autores: Gasparinho, Carolina, Lopes, Ângela, Castro, Rita, Pereira, Filomena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/155419
Resumo: Publisher Copyright: Copyright © 2023 Yefimenko et al.
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spelling Treponema pallidum infection rate in patients attending the general hospital of Benguela, AngolaAfricaAngolaRPRSyphilisTPHATreponema pallidumRA0421 Public health. Hygiene. Preventive MedicineRG Gynecology and obstetricsQR MicrobiologyQR355 VirologyQR180 ImmunologyParasitologyMicrobiologyInfectious DiseasesVirologyAssessment and DiagnosisImmunology and Microbiology(all)Medical Laboratory TechnologyHealth PolicySDG 3 - Good Health and Well-beingSDG 10 - Reduced InequalitiesSDG 9 - Industry, Innovation, and InfrastructureSDG 8 - Decent Work and Economic GrowthPublisher Copyright: Copyright © 2023 Yefimenko et al.Introduction: The objectives of this study were to estimate the rate of infection by Treponema pallidum and co-infection with Human Immunodeficiency Virus (HIV) in individuals attending the General Hospital of Benguela (GHB), Angola, to verify the Rapid Plasma Reagin (RPR) test performance for its diagnosis when compared with other RPR tests, and to compare a rapid treponemal test with the Treponema pallidum hemagglutination assay (TPHA). Methodology: This is a cross-sectional study carried out between August 2016 and January 2017, at the GHB, 546 individuals attending the emergency room, the outpatient service or hospitalized at the GHB were included. All the samples were tested at the GHB with the routine hospital RPR test and a rapid treponemal test. The samples were then transported to the Institute of Hygiene and Tropical Medicine (IHMT) where RPR testing and TPHA testing were performed. Results: The rate of T. pallidum active infection, demonstrated by a reactive RPR and TPHA result, was 2.9%, of which 81.2% corresponded to indeterminate latent syphilis and 18.8% to secondary syphilis. HIV co-infection was detected in 62.5% of individuals diagnosed with syphilis. Past infection, defined as a non-reactive RPR and reactive TPHA test, was diagnosed in 4.1% of individuals. Conclusions: The high rate of syphilis/HIV co-infection emphasizes the urgent requirement for adequate sexually transmitted infections (STIs) screening, prevention and treatment programs. In addition, implementation of quality control measures within RPR testing protocols at GHB are needed, including training for laboratory personnel, adequate equipment and introduction of other rapid testing.Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)Population health, policies and services (PPS)RUNYefimenko, LesyaGasparinho, CarolinaLopes, ÂngelaCastro, RitaPereira, Filomena2023-07-17T22:15:44Z2023-012023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4application/pdfhttp://hdl.handle.net/10362/155419eng2036-6590PURE: 64657352https://doi.org/10.3855/jidc.17122info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:37:59Zoai:run.unl.pt:10362/155419Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:56:03.365923Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
title Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
spellingShingle Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
Yefimenko, Lesya
Africa
Angola
RPR
Syphilis
TPHA
Treponema pallidum
RA0421 Public health. Hygiene. Preventive Medicine
RG Gynecology and obstetrics
QR Microbiology
QR355 Virology
QR180 Immunology
Parasitology
Microbiology
Infectious Diseases
Virology
Assessment and Diagnosis
Immunology and Microbiology(all)
Medical Laboratory Technology
Health Policy
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
SDG 9 - Industry, Innovation, and Infrastructure
SDG 8 - Decent Work and Economic Growth
title_short Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
title_full Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
title_fullStr Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
title_full_unstemmed Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
title_sort Treponema pallidum infection rate in patients attending the general hospital of Benguela, Angola
author Yefimenko, Lesya
author_facet Yefimenko, Lesya
Gasparinho, Carolina
Lopes, Ângela
Castro, Rita
Pereira, Filomena
author_role author
author2 Gasparinho, Carolina
Lopes, Ângela
Castro, Rita
Pereira, Filomena
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Global Health and Tropical Medicine (GHTM)
Instituto de Higiene e Medicina Tropical (IHMT)
Population health, policies and services (PPS)
RUN
dc.contributor.author.fl_str_mv Yefimenko, Lesya
Gasparinho, Carolina
Lopes, Ângela
Castro, Rita
Pereira, Filomena
dc.subject.por.fl_str_mv Africa
Angola
RPR
Syphilis
TPHA
Treponema pallidum
RA0421 Public health. Hygiene. Preventive Medicine
RG Gynecology and obstetrics
QR Microbiology
QR355 Virology
QR180 Immunology
Parasitology
Microbiology
Infectious Diseases
Virology
Assessment and Diagnosis
Immunology and Microbiology(all)
Medical Laboratory Technology
Health Policy
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
SDG 9 - Industry, Innovation, and Infrastructure
SDG 8 - Decent Work and Economic Growth
topic Africa
Angola
RPR
Syphilis
TPHA
Treponema pallidum
RA0421 Public health. Hygiene. Preventive Medicine
RG Gynecology and obstetrics
QR Microbiology
QR355 Virology
QR180 Immunology
Parasitology
Microbiology
Infectious Diseases
Virology
Assessment and Diagnosis
Immunology and Microbiology(all)
Medical Laboratory Technology
Health Policy
SDG 3 - Good Health and Well-being
SDG 10 - Reduced Inequalities
SDG 9 - Industry, Innovation, and Infrastructure
SDG 8 - Decent Work and Economic Growth
description Publisher Copyright: Copyright © 2023 Yefimenko et al.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-17T22:15:44Z
2023-01
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/155419
url http://hdl.handle.net/10362/155419
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2036-6590
PURE: 64657352
https://doi.org/10.3855/jidc.17122
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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