Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration

Detalhes bibliográficos
Autor(a) principal: Gavinho, Sílvia Rodrigues
Data de Publicação: 2023
Outros Autores: Pádua, Ana Sofia, Holz, Laura Isabel Vilas, Sá-Nogueira, Isabel, Silva, Jorge Carvalho, Borges, João Paulo, Valente, Manuel Almeida, Graça, Manuel Pedro Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/162707
Resumo: The authors extend their appreciation to the FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2020, UIDP/50025/2020, and UIDB/50025/2020 of the Associate Laboratory Institute of Nanostructures, Nanomodelling, and Nanofabrication—i3N., UCIBIO (UIDP/04378/2020 and UIDB/04378/2020) and Associate Laboratory i4HB (LA/P/0140/2020) and TEMA (UIDB/00481/2020 and UIDP/00481/2020). Publisher Copyright: © 2023 by the authors.
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spelling Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regenerationantibacterial activitybioactive glassbioactivitybone regenerationdental applicationsimplant coatingsmagnesiumstrontiumtissue engineeringChemical Engineering(all)Materials Science(all)The authors extend their appreciation to the FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2020, UIDP/50025/2020, and UIDB/50025/2020 of the Associate Laboratory Institute of Nanostructures, Nanomodelling, and Nanofabrication—i3N., UCIBIO (UIDP/04378/2020 and UIDB/04378/2020) and Associate Laboratory i4HB (LA/P/0140/2020) and TEMA (UIDB/00481/2020 and UIDP/00481/2020). Publisher Copyright: © 2023 by the authors.The non-surgical treatments are being required to reconstruct damaged tissue, prioritizing our body’s natural healing process. Thus, the use of bioactive materials such as bioactive glass has been studied to support the repair and restoration of hard and soft tissue. Thus, in this work Bioglass 45S5 was developed, adding 1 and 2%mol of SrO or MgO and the physical and biological properties were evaluated. The addition of MgO and SrO at the studied concentrations promoted the slight increase in non-bridging oxygens number, observed through the temperature shift in phase transitions to lower values compared to Bioglass 45S5. The insertion of the ions also showed a positive effect on Saos-2 cell viability, decreasing the cytotoxic of Bioglass 45S5. Besides the Ca/P ratio on the pellets surface demonstrating no evidence of higher reactivity between Bioglass 45S5 and Bioglass with Sr and Mg, micrographs show that at 24 h the Ca/P rich layer is denser than in Bioglass 45S5 after the contact with simulated body fluid. The samples with Sr and Mg show a higher antibacterial effect compared to Bioglass 45S5. The addition of the studied ions may benefit the biological response of Bioglass 45S5 in dental applications as scaffolds or coatings.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DF – Departamento de FísicaUCIBIO - Applied Molecular Biosciences UnitDCV - Departamento de Ciências da VidaDCM - Departamento de Ciência dos MateriaisRUNGavinho, Sílvia RodriguesPádua, Ana SofiaHolz, Laura Isabel VilasSá-Nogueira, IsabelSilva, Jorge CarvalhoBorges, João PauloValente, Manuel AlmeidaGraça, Manuel Pedro Fernandes2024-01-24T16:59:54Z2023-10-062023-10-06T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article17application/pdfhttp://hdl.handle.net/10362/162707eng2079-4991PURE: 81995338https://doi.org/10.3390/nano13192717info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:45:39Zoai:run.unl.pt:10362/162707Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:02.026624Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
title Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
spellingShingle Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
Gavinho, Sílvia Rodrigues
antibacterial activity
bioactive glass
bioactivity
bone regeneration
dental applications
implant coatings
magnesium
strontium
tissue engineering
Chemical Engineering(all)
Materials Science(all)
title_short Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
title_full Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
title_fullStr Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
title_full_unstemmed Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
title_sort Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
author Gavinho, Sílvia Rodrigues
author_facet Gavinho, Sílvia Rodrigues
Pádua, Ana Sofia
Holz, Laura Isabel Vilas
Sá-Nogueira, Isabel
Silva, Jorge Carvalho
Borges, João Paulo
Valente, Manuel Almeida
Graça, Manuel Pedro Fernandes
author_role author
author2 Pádua, Ana Sofia
Holz, Laura Isabel Vilas
Sá-Nogueira, Isabel
Silva, Jorge Carvalho
Borges, João Paulo
Valente, Manuel Almeida
Graça, Manuel Pedro Fernandes
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DF – Departamento de Física
UCIBIO - Applied Molecular Biosciences Unit
DCV - Departamento de Ciências da Vida
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Gavinho, Sílvia Rodrigues
Pádua, Ana Sofia
Holz, Laura Isabel Vilas
Sá-Nogueira, Isabel
Silva, Jorge Carvalho
Borges, João Paulo
Valente, Manuel Almeida
Graça, Manuel Pedro Fernandes
dc.subject.por.fl_str_mv antibacterial activity
bioactive glass
bioactivity
bone regeneration
dental applications
implant coatings
magnesium
strontium
tissue engineering
Chemical Engineering(all)
Materials Science(all)
topic antibacterial activity
bioactive glass
bioactivity
bone regeneration
dental applications
implant coatings
magnesium
strontium
tissue engineering
Chemical Engineering(all)
Materials Science(all)
description The authors extend their appreciation to the FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2020, UIDP/50025/2020, and UIDB/50025/2020 of the Associate Laboratory Institute of Nanostructures, Nanomodelling, and Nanofabrication—i3N., UCIBIO (UIDP/04378/2020 and UIDB/04378/2020) and Associate Laboratory i4HB (LA/P/0140/2020) and TEMA (UIDB/00481/2020 and UIDP/00481/2020). Publisher Copyright: © 2023 by the authors.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-06
2023-10-06T00:00:00Z
2024-01-24T16:59:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/162707
url http://hdl.handle.net/10362/162707
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-4991
PURE: 81995338
https://doi.org/10.3390/nano13192717
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 17
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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