Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering

Detalhes bibliográficos
Autor(a) principal: Trindade, Daniela
Data de Publicação: 2021
Outros Autores: Cordeiro, Rachel, José, Henrique Cardoso, Ângelo, David, Alves, Nuno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/48718
Resumo: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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spelling Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineeringTemporomandibular joint discFibrocartilageDisc dysfunctionsTissue engineeringDecellularization© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).The temporomandibular joint (TMJ) is an important structure for the masticatory system and the pathologies associated with it affect a large part of the population and impair people’s lifestyle. It comprises an articular disc, that presents low regeneration capacities and the existing clinical options for repairing it are not effective. This way, it is imperative to achieve a permanent solution to guarantee a good quality of life for people who suffer from these pathologies. Complete knowledge of the unique characteristics of the disc will make it easier to achieve a successful tissue engineering (TE) construct. Thus, the search for an effective, safe and lasting solution has already started, including materials that replace the disc, is currently growing. The search for a solution based on TE approaches, which involve regenerating the disc. The present work revises the TMJ disc characteristics and its associated diseases. The different materials used for a total disc replacement are presented, highlighting the TE area. A special focus on future trends in the field and part of the solution for the TMJ problems described in this review will involve the development of a promising engineered disc approach through the use of decellularized extracellular matrices.This work is supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the Project references: UIDB/04044/2020; UIDP/04044/2020; PAMI—ROTEIRO/0328/2013 (Nº 022158), MATIS (CENTRO-01-0145-FEDER-000014), and BIODISCUS (CENTRO-01-0247-FEDER-039969).MDPIRepositório da Universidade de LisboaTrindade, DanielaCordeiro, RachelJosé, Henrique CardosoÂngelo, DavidAlves, Nuno2021-06-23T12:59:10Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/48718engBiomolecules 2021,11, 9310.3390/biom110709332218-273Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:52:06Zoai:repositorio.ul.pt:10451/48718Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:29.328235Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
title Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
spellingShingle Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
Trindade, Daniela
Temporomandibular joint disc
Fibrocartilage
Disc dysfunctions
Tissue engineering
Decellularization
title_short Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
title_full Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
title_fullStr Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
title_full_unstemmed Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
title_sort Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering
author Trindade, Daniela
author_facet Trindade, Daniela
Cordeiro, Rachel
José, Henrique Cardoso
Ângelo, David
Alves, Nuno
author_role author
author2 Cordeiro, Rachel
José, Henrique Cardoso
Ângelo, David
Alves, Nuno
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Trindade, Daniela
Cordeiro, Rachel
José, Henrique Cardoso
Ângelo, David
Alves, Nuno
dc.subject.por.fl_str_mv Temporomandibular joint disc
Fibrocartilage
Disc dysfunctions
Tissue engineering
Decellularization
topic Temporomandibular joint disc
Fibrocartilage
Disc dysfunctions
Tissue engineering
Decellularization
description © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2021
dc.date.none.fl_str_mv 2021-06-23T12:59:10Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/48718
url http://hdl.handle.net/10451/48718
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Biomolecules 2021,11, 93
10.3390/biom11070933
2218-273X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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