CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS

Detalhes bibliográficos
Autor(a) principal: Sequeira Silva, Ângela
Data de Publicação: 2013
Outros Autores: Rosa, Bruno, Soares, João, Sepodes, Bruno
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25756/rpf.v5i2.52
Resumo: Rheumatoid arthritis is a chronic inflammatory auto-immune disease characterized by a progressive destruction of joints and variable extra-articular manifestations. More prevalent among women, usually develops between 35 and 50 years, and there is a genetic predisposition. The etiology remains unknown but is consensus the importance of T lymphocytes, B lymphocytes and cytokines in the inflammatory process.It is important then to tackle the disease by a multi-disciplinary strand which includes symptoms control with the use of analgesics and anti-inflammatory drugs, and use of glucorticosteroids, disease-modifying drugs and new biological drugs aimed to control disease progression. It’s associated to the pharmacological approach complementary therapies, surgery and patient education programs. This review intended to raise awareness of the complexity of this disease and what the science has offered us, as new strategies pharmacological / non-pharmacological, always with the aim of contributing to an improved quality of life in patients with rheumatoid arthritis.
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spelling CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITISDESAFIOS E OPORTUNIDADES NA ABORDAGEM TERAPÊUTICA DA ARTRITE REUMATOIDERheumatoid arthritis is a chronic inflammatory auto-immune disease characterized by a progressive destruction of joints and variable extra-articular manifestations. More prevalent among women, usually develops between 35 and 50 years, and there is a genetic predisposition. The etiology remains unknown but is consensus the importance of T lymphocytes, B lymphocytes and cytokines in the inflammatory process.It is important then to tackle the disease by a multi-disciplinary strand which includes symptoms control with the use of analgesics and anti-inflammatory drugs, and use of glucorticosteroids, disease-modifying drugs and new biological drugs aimed to control disease progression. It’s associated to the pharmacological approach complementary therapies, surgery and patient education programs. This review intended to raise awareness of the complexity of this disease and what the science has offered us, as new strategies pharmacological / non-pharmacological, always with the aim of contributing to an improved quality of life in patients with rheumatoid arthritis.A artrite reumatoide é uma doença inflamatória crónica autoimune, caracterizada por uma destruição progressiva das articulações e manifestações extra-articulares variáveis. Mais prevalente no sexo feminino, inicia-se normalmente entre os 35 e 50 anos, verificando-se marcada predisposição genética. A etiologia da doença é desconhecida, mas é consensual a importância dos linfócitos T, linfócitos B e citocinas no processo inflamatório. É importante abordar esta patologia numa vertente multidisciplinar que englobe o controlo da sintomatologia, com recurso a analgésicos e anti-inflamatórios não-esteroides, e a utilização de corticosteroides, fármacos modificadores da doença e de novas terapêuticas biológicas, com o objetivo de controlar a progressão da doença. À abordagem farmacológica associam-se terapias complementares, cirurgia e programas de educação do doente. Através desta revisão pretende-se dar a conhecer a complexidade desta doença e o que a ciência nos tem oferecido, como novas estratégias farmacológicas/não farmacológicas, sempre com o objetivo de contribuir para uma melhoria da qualidade de vida dos doentes com artrite reumatoide.Formifarma2013-06-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25756/rpf.v5i2.52https://doi.org/10.25756/rpf.v5i2.52Revista Portuguesa de Farmacoterapia / Portuguese Journal of Pharmacotherapy; Vol 5 No 2 (2013): Abril; 41-50Revista Portuguesa de Farmacoterapia; v. 5 n. 2 (2013): Abril; 41-502183-73411647-354Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://revista.farmacoterapia.pt/index.php/rpf/article/view/52http://revista.farmacoterapia.pt/index.php/rpf/article/view/52/41Direitos de Autor (c) 2017 Revista Portuguesa de Farmacoterapiahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessSequeira Silva, ÂngelaRosa, BrunoSoares, JoãoSepodes, Bruno2023-09-01T04:33:07Zoai:ojs.farmacoterapia.pt:article/52Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:11:31.607959Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
DESAFIOS E OPORTUNIDADES NA ABORDAGEM TERAPÊUTICA DA ARTRITE REUMATOIDE
title CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
spellingShingle CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
Sequeira Silva, Ângela
title_short CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
title_full CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
title_fullStr CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
title_full_unstemmed CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
title_sort CHALLENGES AND OPPORTUNITIES IN APPROACH THERAPY OF RHEUMATOID ARTHRITIS
author Sequeira Silva, Ângela
author_facet Sequeira Silva, Ângela
Rosa, Bruno
Soares, João
Sepodes, Bruno
author_role author
author2 Rosa, Bruno
Soares, João
Sepodes, Bruno
author2_role author
author
author
dc.contributor.author.fl_str_mv Sequeira Silva, Ângela
Rosa, Bruno
Soares, João
Sepodes, Bruno
description Rheumatoid arthritis is a chronic inflammatory auto-immune disease characterized by a progressive destruction of joints and variable extra-articular manifestations. More prevalent among women, usually develops between 35 and 50 years, and there is a genetic predisposition. The etiology remains unknown but is consensus the importance of T lymphocytes, B lymphocytes and cytokines in the inflammatory process.It is important then to tackle the disease by a multi-disciplinary strand which includes symptoms control with the use of analgesics and anti-inflammatory drugs, and use of glucorticosteroids, disease-modifying drugs and new biological drugs aimed to control disease progression. It’s associated to the pharmacological approach complementary therapies, surgery and patient education programs. This review intended to raise awareness of the complexity of this disease and what the science has offered us, as new strategies pharmacological / non-pharmacological, always with the aim of contributing to an improved quality of life in patients with rheumatoid arthritis.
publishDate 2013
dc.date.none.fl_str_mv 2013-06-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.25756/rpf.v5i2.52
https://doi.org/10.25756/rpf.v5i2.52
url https://doi.org/10.25756/rpf.v5i2.52
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv http://revista.farmacoterapia.pt/index.php/rpf/article/view/52
http://revista.farmacoterapia.pt/index.php/rpf/article/view/52/41
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2017 Revista Portuguesa de Farmacoterapia
http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2017 Revista Portuguesa de Farmacoterapia
http://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Formifarma
publisher.none.fl_str_mv Formifarma
dc.source.none.fl_str_mv Revista Portuguesa de Farmacoterapia / Portuguese Journal of Pharmacotherapy; Vol 5 No 2 (2013): Abril; 41-50
Revista Portuguesa de Farmacoterapia; v. 5 n. 2 (2013): Abril; 41-50
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