Non-progressive leukoencephalopathy with bilateral temporal cysts

Detalhes bibliográficos
Autor(a) principal: Gomes, A
Data de Publicação: 2001
Outros Autores: Vieira, J, Saldanha, J
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.10/677
Resumo: We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood.
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spelling Non-progressive leukoencephalopathy with bilateral temporal cystsInfecções por citomegalovirusDoenças desmielinizantesCytomegalovirus infectionsDemyelinating diseasesLeukoencephalopathyWe report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood.SaundersRepositório do Hospital Prof. Doutor Fernando FonsecaGomes, AVieira, JSaldanha, J2012-08-29T10:52:15Z2001-01-01T00:00:00Z2001-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/677engEur J Paediatr Neurol. 2001;5(3):121-51090-3798info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:51:33Zoai:repositorio.hff.min-saude.pt:10400.10/677Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:51:54.712299Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Non-progressive leukoencephalopathy with bilateral temporal cysts
title Non-progressive leukoencephalopathy with bilateral temporal cysts
spellingShingle Non-progressive leukoencephalopathy with bilateral temporal cysts
Gomes, A
Infecções por citomegalovirus
Doenças desmielinizantes
Cytomegalovirus infections
Demyelinating diseases
Leukoencephalopathy
title_short Non-progressive leukoencephalopathy with bilateral temporal cysts
title_full Non-progressive leukoencephalopathy with bilateral temporal cysts
title_fullStr Non-progressive leukoencephalopathy with bilateral temporal cysts
title_full_unstemmed Non-progressive leukoencephalopathy with bilateral temporal cysts
title_sort Non-progressive leukoencephalopathy with bilateral temporal cysts
author Gomes, A
author_facet Gomes, A
Vieira, J
Saldanha, J
author_role author
author2 Vieira, J
Saldanha, J
author2_role author
author
dc.contributor.none.fl_str_mv Repositório do Hospital Prof. Doutor Fernando Fonseca
dc.contributor.author.fl_str_mv Gomes, A
Vieira, J
Saldanha, J
dc.subject.por.fl_str_mv Infecções por citomegalovirus
Doenças desmielinizantes
Cytomegalovirus infections
Demyelinating diseases
Leukoencephalopathy
topic Infecções por citomegalovirus
Doenças desmielinizantes
Cytomegalovirus infections
Demyelinating diseases
Leukoencephalopathy
description We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood.
publishDate 2001
dc.date.none.fl_str_mv 2001-01-01T00:00:00Z
2001-01-01T00:00:00Z
2012-08-29T10:52:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.10/677
url http://hdl.handle.net/10400.10/677
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eur J Paediatr Neurol. 2001;5(3):121-5
1090-3798
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dc.publisher.none.fl_str_mv Saunders
publisher.none.fl_str_mv Saunders
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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