Non-progressive leukoencephalopathy with bilateral temporal cysts
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.10/677 |
Resumo: | We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
Non-progressive leukoencephalopathy with bilateral temporal cystsInfecções por citomegalovirusDoenças desmielinizantesCytomegalovirus infectionsDemyelinating diseasesLeukoencephalopathyWe report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood.SaundersRepositório do Hospital Prof. Doutor Fernando FonsecaGomes, AVieira, JSaldanha, J2012-08-29T10:52:15Z2001-01-01T00:00:00Z2001-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/677engEur J Paediatr Neurol. 2001;5(3):121-51090-3798info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:51:33Zoai:repositorio.hff.min-saude.pt:10400.10/677Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:51:54.712299Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
title |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
spellingShingle |
Non-progressive leukoencephalopathy with bilateral temporal cysts Gomes, A Infecções por citomegalovirus Doenças desmielinizantes Cytomegalovirus infections Demyelinating diseases Leukoencephalopathy |
title_short |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
title_full |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
title_fullStr |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
title_full_unstemmed |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
title_sort |
Non-progressive leukoencephalopathy with bilateral temporal cysts |
author |
Gomes, A |
author_facet |
Gomes, A Vieira, J Saldanha, J |
author_role |
author |
author2 |
Vieira, J Saldanha, J |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Repositório do Hospital Prof. Doutor Fernando Fonseca |
dc.contributor.author.fl_str_mv |
Gomes, A Vieira, J Saldanha, J |
dc.subject.por.fl_str_mv |
Infecções por citomegalovirus Doenças desmielinizantes Cytomegalovirus infections Demyelinating diseases Leukoencephalopathy |
topic |
Infecções por citomegalovirus Doenças desmielinizantes Cytomegalovirus infections Demyelinating diseases Leukoencephalopathy |
description |
We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-01-01T00:00:00Z 2001-01-01T00:00:00Z 2012-08-29T10:52:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.10/677 |
url |
http://hdl.handle.net/10400.10/677 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eur J Paediatr Neurol. 2001;5(3):121-5 1090-3798 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Saunders |
publisher.none.fl_str_mv |
Saunders |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130383339487232 |