Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/2341 |
Resumo: | We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood. |
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Non-Progressive Leukoencephalopathy with Bilateral Temporal CystsCentral Nervous System Cysts/diagnosisCerebral Cortex/pathologyCytomegalovirus Infections/congenitalCytomegalovirus Infections/diagnosisDemyelinating Diseases/diagnosisDiagnosis, DifferentialDominance, Cerebral/physiologyIntellectual Disability/diagnosisMagnetic Resonance ImagingChildInfant, Low Birth WeightFollow-Up StudiesHDE NEU PEDWe report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood.ElsevierRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEGomes, ALVieira, JPSaldanha, J2015-11-11T13:02:27Z20012001-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2341engEur J Paediatr Neurol. 2001;5(3):121-5.10.1053/ejpn.2001.0482info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:36:30Zoai:repositorio.chlc.min-saude.pt:10400.17/2341Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:19:42.169453Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
title |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
spellingShingle |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts Gomes, AL Central Nervous System Cysts/diagnosis Cerebral Cortex/pathology Cytomegalovirus Infections/congenital Cytomegalovirus Infections/diagnosis Demyelinating Diseases/diagnosis Diagnosis, Differential Dominance, Cerebral/physiology Intellectual Disability/diagnosis Magnetic Resonance Imaging Child Infant, Low Birth Weight Follow-Up Studies HDE NEU PED |
title_short |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
title_full |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
title_fullStr |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
title_full_unstemmed |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
title_sort |
Non-Progressive Leukoencephalopathy with Bilateral Temporal Cysts |
author |
Gomes, AL |
author_facet |
Gomes, AL Vieira, JP Saldanha, J |
author_role |
author |
author2 |
Vieira, JP Saldanha, J |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Gomes, AL Vieira, JP Saldanha, J |
dc.subject.por.fl_str_mv |
Central Nervous System Cysts/diagnosis Cerebral Cortex/pathology Cytomegalovirus Infections/congenital Cytomegalovirus Infections/diagnosis Demyelinating Diseases/diagnosis Diagnosis, Differential Dominance, Cerebral/physiology Intellectual Disability/diagnosis Magnetic Resonance Imaging Child Infant, Low Birth Weight Follow-Up Studies HDE NEU PED |
topic |
Central Nervous System Cysts/diagnosis Cerebral Cortex/pathology Cytomegalovirus Infections/congenital Cytomegalovirus Infections/diagnosis Demyelinating Diseases/diagnosis Diagnosis, Differential Dominance, Cerebral/physiology Intellectual Disability/diagnosis Magnetic Resonance Imaging Child Infant, Low Birth Weight Follow-Up Studies HDE NEU PED |
description |
We report two cases of a peculiar leukoencephalopathy with temporal cysts. Both patients have a non-progressive neurological disorder with mental retardation, microcephaly and sensorineural deafness although clinical differences between them may reflect a different aetiology. The metabolic disorders with white matter involvement and the recently described leukoencephalopathies (Van Der Knaap disease, 'vanishing white matter disease') were excluded based on clinical, biologic and imaging findings. Cytomegalovirus infection is a likely possibility in the first case although the magnetic resonance imaging picture is only partially similar to previously reported cases. Our patients are strikingly similar to the patients reported by Deonna et al. and Olivier et al. We discuss the clinical and imaging findings in our patients and the differential diagnosis considering the known disorders of the white matter in childhood. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001 2001-01-01T00:00:00Z 2015-11-11T13:02:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/2341 |
url |
http://hdl.handle.net/10400.17/2341 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eur J Paediatr Neurol. 2001;5(3):121-5. 10.1053/ejpn.2001.0482 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131293754064896 |