earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned

Detalhes bibliográficos
Autor(a) principal: Martins, Carla
Data de Publicação: 2022
Outros Autores: Assunção, Ricardo, Costa, Ana, Serrano, Débora, Visintin, Lia, De Boevre, Marthe, Lachat, Carl, Vidal, Arnau, De Saeger, Sarah, Namorado, Sónia, Vidigal, Cristina, Almeida, Elisabete, Alvito, Paula, Nunes, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8292
Resumo: This article belongs to the Special Issue Environmental Exposures and Epidemiological Studies on Maternal and Child Health
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spelling earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons LearnedMycotoxinsEarly-life ExposureBirth CohortsExposomeEarlyMYCOMicotoxinasExposição no Início de VidaExpossomaEstados de Saúde e de DoençaDeterminantes da Saúde e da DoençaSegurança AlimentarToxicologiaAvaliação do RiscoPortugalThis article belongs to the Special Issue Environmental Exposures and Epidemiological Studies on Maternal and Child HealthEarly-life exposure occurs during gestation through transfer to the fetus and later, during lactation. Recent monitoring data revealed that the Portuguese population is exposed to mycotoxins, including young children. This study aimed to develop a pilot study to assess the early-life exposure to mycotoxins through a mother-child cohort, and to identify the associated challenges. Participants were recruited during pregnancy (1st trimester) and followed-up in three moments of observation: 2nd trimester of pregnancy (mother), and 1st and 6th month of the child's life (mother and child), with the collection of biological samples and sociodemographic and food consumption data. The earlyMYCO pilot study enrolled 19 mother-child pairs. The analysis of biological samples from participants revealed the presence of 4 out of 15 and 5 out of 18 mycotoxins' biomarkers of exposure in urine and breast milk samples, respectively. The main aspects identified as contributors for the successful development of the cohort were the multidisciplinary and dedicated team members in healthcare units, reduced burden of participation, and the availability of healthcare units for the implementation of the fieldwork. Challenges faced, lessons learned, and suggestions were discussed as a contribution for the development of further studies in this area.The earlyMYCO study was funded by Foundation for Science and Technology (PTDC/DTPMEDTOX/28762/2017), by CESAM (UIDP/50017/2020+UIDB/50017/2020+LA/P/0094/2020) and by the project MYTOX-SOUTH, Ghent University Global Minds programme.MDPIRepositório Científico do Instituto Nacional de SaúdeMartins, CarlaAssunção, RicardoCosta, AnaSerrano, DéboraVisintin, LiaDe Boevre, MartheLachat, CarlVidal, ArnauDe Saeger, SarahNamorado, SóniaVidigal, CristinaAlmeida, ElisabeteAlvito, PaulaNunes, Carla2022-11-02T12:49:04Z2022-06-232022-06-23T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8292engInt J Environ Res Public Health. 2022 Jun 23;19(13):7716. doi: 10.3390/ijerph191377161661-782710.3390/ijerph19137716info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:31Zoai:repositorio.insa.pt:10400.18/8292Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:59.406385Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
title earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
spellingShingle earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
Martins, Carla
Mycotoxins
Early-life Exposure
Birth Cohorts
Exposome
EarlyMYCO
Micotoxinas
Exposição no Início de Vida
Expossoma
Estados de Saúde e de Doença
Determinantes da Saúde e da Doença
Segurança Alimentar
Toxicologia
Avaliação do Risco
Portugal
title_short earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
title_full earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
title_fullStr earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
title_full_unstemmed earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
title_sort earlyMYCO: A Pilot Mother-Child Cohort Study to Assess Early-Life Exposure to Mycotoxins - Challenges and Lessons Learned
author Martins, Carla
author_facet Martins, Carla
Assunção, Ricardo
Costa, Ana
Serrano, Débora
Visintin, Lia
De Boevre, Marthe
Lachat, Carl
Vidal, Arnau
De Saeger, Sarah
Namorado, Sónia
Vidigal, Cristina
Almeida, Elisabete
Alvito, Paula
Nunes, Carla
author_role author
author2 Assunção, Ricardo
Costa, Ana
Serrano, Débora
Visintin, Lia
De Boevre, Marthe
Lachat, Carl
Vidal, Arnau
De Saeger, Sarah
Namorado, Sónia
Vidigal, Cristina
Almeida, Elisabete
Alvito, Paula
Nunes, Carla
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Martins, Carla
Assunção, Ricardo
Costa, Ana
Serrano, Débora
Visintin, Lia
De Boevre, Marthe
Lachat, Carl
Vidal, Arnau
De Saeger, Sarah
Namorado, Sónia
Vidigal, Cristina
Almeida, Elisabete
Alvito, Paula
Nunes, Carla
dc.subject.por.fl_str_mv Mycotoxins
Early-life Exposure
Birth Cohorts
Exposome
EarlyMYCO
Micotoxinas
Exposição no Início de Vida
Expossoma
Estados de Saúde e de Doença
Determinantes da Saúde e da Doença
Segurança Alimentar
Toxicologia
Avaliação do Risco
Portugal
topic Mycotoxins
Early-life Exposure
Birth Cohorts
Exposome
EarlyMYCO
Micotoxinas
Exposição no Início de Vida
Expossoma
Estados de Saúde e de Doença
Determinantes da Saúde e da Doença
Segurança Alimentar
Toxicologia
Avaliação do Risco
Portugal
description This article belongs to the Special Issue Environmental Exposures and Epidemiological Studies on Maternal and Child Health
publishDate 2022
dc.date.none.fl_str_mv 2022-11-02T12:49:04Z
2022-06-23
2022-06-23T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8292
url http://hdl.handle.net/10400.18/8292
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Environ Res Public Health. 2022 Jun 23;19(13):7716. doi: 10.3390/ijerph19137716
1661-7827
10.3390/ijerph19137716
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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