Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis.
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/23345 |
Resumo: | Objectives. To test the relation between white matter lesions (WML) location and physical performance, in aged patients. Methods. SUBJECTS: 29 patients (17 males), aged >65 (mean age 72.6 ± 5.2), with leukoaraiosis. WML was quantified with a visual scale; Apparent Diffusion Coefficient (ADC) was measured bilaterally in frontal periventricular lesioned white matter and frontal and parieto-occipital normal appearing white matter (NAWM). Motor performance was studied using the Short Physical Performance Battery (SPPB), single leg stand time, finger tapping and grooved pegboard tests (GPT). Results. There were significant correlations between the frontal region visual scale scores and SPPB chair stands (r = -0.379; P = .039) and Grooved Pegboard (r = 0.393; P = .032); frontal NAWM ADC values and SPPB standing balance (r = -0.450; P = .014) and SPPB 4 meter walk (r = -0.379; P = .043). Conclusion. Frontal WML are negatively related to motor performance in patients with leukoaraiosis. DWI results suggest that this may be true even for NAWM. |
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Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis.Objectives. To test the relation between white matter lesions (WML) location and physical performance, in aged patients. Methods. SUBJECTS: 29 patients (17 males), aged >65 (mean age 72.6 ± 5.2), with leukoaraiosis. WML was quantified with a visual scale; Apparent Diffusion Coefficient (ADC) was measured bilaterally in frontal periventricular lesioned white matter and frontal and parieto-occipital normal appearing white matter (NAWM). Motor performance was studied using the Short Physical Performance Battery (SPPB), single leg stand time, finger tapping and grooved pegboard tests (GPT). Results. There were significant correlations between the frontal region visual scale scores and SPPB chair stands (r = -0.379; P = .039) and Grooved Pegboard (r = 0.393; P = .032); frontal NAWM ADC values and SPPB standing balance (r = -0.450; P = .014) and SPPB 4 meter walk (r = -0.379; P = .043). Conclusion. Frontal WML are negatively related to motor performance in patients with leukoaraiosis. DWI results suggest that this may be true even for NAWM.Centro de Estudos de Doenças Crónicas (CEDOC)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNBaptista, Miguel VianaBugalho, PauloJordão, ConstançaRibeiro, OlgaPina, José A EsperançaFerro, José2017-09-18T22:00:22Z2011-05-152011-05-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6application/pdfhttp://hdl.handle.net/10362/23345eng2090-2204PURE: 127112https://doi.org/10.4061/2011/950341info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:11:35Zoai:run.unl.pt:10362/23345Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:27:45.839305Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
title |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
spellingShingle |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. Baptista, Miguel Viana |
title_short |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
title_full |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
title_fullStr |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
title_full_unstemmed |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
title_sort |
Motor dysfunction correlates with frontal white matter ischemic changes in patients with leukoaraiosis. |
author |
Baptista, Miguel Viana |
author_facet |
Baptista, Miguel Viana Bugalho, Paulo Jordão, Constança Ribeiro, Olga Pina, José A Esperança Ferro, José |
author_role |
author |
author2 |
Bugalho, Paulo Jordão, Constança Ribeiro, Olga Pina, José A Esperança Ferro, José |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Centro de Estudos de Doenças Crónicas (CEDOC) NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Baptista, Miguel Viana Bugalho, Paulo Jordão, Constança Ribeiro, Olga Pina, José A Esperança Ferro, José |
description |
Objectives. To test the relation between white matter lesions (WML) location and physical performance, in aged patients. Methods. SUBJECTS: 29 patients (17 males), aged >65 (mean age 72.6 ± 5.2), with leukoaraiosis. WML was quantified with a visual scale; Apparent Diffusion Coefficient (ADC) was measured bilaterally in frontal periventricular lesioned white matter and frontal and parieto-occipital normal appearing white matter (NAWM). Motor performance was studied using the Short Physical Performance Battery (SPPB), single leg stand time, finger tapping and grooved pegboard tests (GPT). Results. There were significant correlations between the frontal region visual scale scores and SPPB chair stands (r = -0.379; P = .039) and Grooved Pegboard (r = 0.393; P = .032); frontal NAWM ADC values and SPPB standing balance (r = -0.450; P = .014) and SPPB 4 meter walk (r = -0.379; P = .043). Conclusion. Frontal WML are negatively related to motor performance in patients with leukoaraiosis. DWI results suggest that this may be true even for NAWM. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-05-15 2011-05-15T00:00:00Z 2017-09-18T22:00:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/23345 |
url |
http://hdl.handle.net/10362/23345 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2090-2204 PURE: 127112 https://doi.org/10.4061/2011/950341 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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6 application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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