Congenital chylothorax: A series of eight cases

Detalhes bibliográficos
Autor(a) principal: Jorge Antunes, Joana
Data de Publicação: 2023
Outros Autores: Borges, Madalena, Mascarenhas, Andreia, Brito, Sara, Iglesias, Célia, Fernandes, Eduardo, Vieira, Eunice, Pinto, Filomena, Ferreira, Leonor, Tomé, Teresa, Nona, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v32.i3.25442
Resumo: Introduction: Congenital chylothorax (CC) is the accumulation of lymph in the pleural space. The aim of this study was to review the cases of CC diagnosed in newborns admitted to a level III neonatal intensive care unit between January 2014 and December 2020. Results: Eight cases of CC were identified, all with prenatal diagnosis. After postnatal confirmation of the diagnosis, supportive care and conservative therapy were initiated. Six cases underwent mechanical ventilation, two were treated with surfactant and inhaled nitric oxide, four required inotropic support, and one underwent extracorporeal membrane oxygenation. Five newborns were effectively treated with octreotide. One patient with hydrops fetalis died after birth. Discussion: The prognosis of CC depends on the severity of the effusion and on associated abnormalities. Medical treatment is based on supportive and conservative treatment. Although the use of octreotide is not unanimous, it proved to be an effective and safe adjuvant therapy in these patients.
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spelling Congenital chylothorax: A series of eight casesQuilotórax congénito: Uma série de oito casosCase ReportsIntroduction: Congenital chylothorax (CC) is the accumulation of lymph in the pleural space. The aim of this study was to review the cases of CC diagnosed in newborns admitted to a level III neonatal intensive care unit between January 2014 and December 2020. Results: Eight cases of CC were identified, all with prenatal diagnosis. After postnatal confirmation of the diagnosis, supportive care and conservative therapy were initiated. Six cases underwent mechanical ventilation, two were treated with surfactant and inhaled nitric oxide, four required inotropic support, and one underwent extracorporeal membrane oxygenation. Five newborns were effectively treated with octreotide. One patient with hydrops fetalis died after birth. Discussion: The prognosis of CC depends on the severity of the effusion and on associated abnormalities. Medical treatment is based on supportive and conservative treatment. Although the use of octreotide is not unanimous, it proved to be an effective and safe adjuvant therapy in these patients.Introdução: O quilotórax congénito consiste na acumulação de linfa no espaço pleural. O objetivo deste estudo foi analisar os casos de recém-nascidos com diagnóstico de quilotórax congénito admitidos numa unidade de cuidados intensivos neonatais de nível III entre janeiro de 2014 e dezembro de 2020. Resultados: Foram identificados oito casos de quilotórax congénito, todos com diagnóstico pré-natal. Após confirmação pós-natal do diagnóstico, foi iniciado tratamento de suporte e conservador. Seis casos foram submetidos a ventilação mecânica invasiva, dois foram tratados com surfactante e óxido nítrico inalado, quatro tiveram necessidade de suporte inotrópico e um recebeu oxigenação por membrana extracorporal. Cinco casos foram efetivamente tratados com octreótido. Um recém-nascido com hidrópsia fetal faleceu após o nascimento. Discussão: O prognóstico do quilotórax congénito depende da gravidade do derrame pleural e das anomalias associadas. O tratamento inicial deve ser de suporte e conservador. Embora a utilização de octreótido não seja consensual, demonstrou ser uma terapêutica efetiva e segura nesta amostra de doentes.Centro Hospitalar Universitário de Santo António2023-11-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v32.i3.25442eng2183-9417Jorge Antunes, JoanaBorges, MadalenaMascarenhas, AndreiaBrito, SaraIglesias, CéliaFernandes, EduardoVieira, EunicePinto, FilomenaFerreira, LeonorTomé, TeresaNona, Joséinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-16T17:28:48Zoai:ojs.revistas.rcaap.pt:article/25442Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:53:51.688014Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Congenital chylothorax: A series of eight cases
Quilotórax congénito: Uma série de oito casos
title Congenital chylothorax: A series of eight cases
spellingShingle Congenital chylothorax: A series of eight cases
Jorge Antunes, Joana
Case Reports
title_short Congenital chylothorax: A series of eight cases
title_full Congenital chylothorax: A series of eight cases
title_fullStr Congenital chylothorax: A series of eight cases
title_full_unstemmed Congenital chylothorax: A series of eight cases
title_sort Congenital chylothorax: A series of eight cases
author Jorge Antunes, Joana
author_facet Jorge Antunes, Joana
Borges, Madalena
Mascarenhas, Andreia
Brito, Sara
Iglesias, Célia
Fernandes, Eduardo
Vieira, Eunice
Pinto, Filomena
Ferreira, Leonor
Tomé, Teresa
Nona, José
author_role author
author2 Borges, Madalena
Mascarenhas, Andreia
Brito, Sara
Iglesias, Célia
Fernandes, Eduardo
Vieira, Eunice
Pinto, Filomena
Ferreira, Leonor
Tomé, Teresa
Nona, José
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Jorge Antunes, Joana
Borges, Madalena
Mascarenhas, Andreia
Brito, Sara
Iglesias, Célia
Fernandes, Eduardo
Vieira, Eunice
Pinto, Filomena
Ferreira, Leonor
Tomé, Teresa
Nona, José
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Introduction: Congenital chylothorax (CC) is the accumulation of lymph in the pleural space. The aim of this study was to review the cases of CC diagnosed in newborns admitted to a level III neonatal intensive care unit between January 2014 and December 2020. Results: Eight cases of CC were identified, all with prenatal diagnosis. After postnatal confirmation of the diagnosis, supportive care and conservative therapy were initiated. Six cases underwent mechanical ventilation, two were treated with surfactant and inhaled nitric oxide, four required inotropic support, and one underwent extracorporeal membrane oxygenation. Five newborns were effectively treated with octreotide. One patient with hydrops fetalis died after birth. Discussion: The prognosis of CC depends on the severity of the effusion and on associated abnormalities. Medical treatment is based on supportive and conservative treatment. Although the use of octreotide is not unanimous, it proved to be an effective and safe adjuvant therapy in these patients.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-16
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v32.i3.25442
url https://doi.org/10.25753/BirthGrowthMJ.v32.i3.25442
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário de Santo António
publisher.none.fl_str_mv Centro Hospitalar Universitário de Santo António
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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