The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483 |
Resumo: | Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations. |
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The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case ReportO Papel dos Alergénios Moleculares no Diagnóstico de Síndrome Gato-Porco: A Propósito de um Caso Clínico RaroCats/immunologyFood Hypersensitivity/immunologyMeat/adverse effectsSerum Albumin/immunologySwine/immunologyAlbumina Sérica/imunologiaCarne/efeitos adversosGato/imunologiaHipersensibilidade Alimentar/imunologiaSuíno/imunologiaCat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.A síndrome do gato-porco é rara, com poucos casos relatados na literatura. Esta patologia é justificada pela homologia entre albuminas séricas de gato e de porco. A evidência sugere que ocorre uma sensibilização primária à albumina sérica de gato Fel d 2, seguida por reações alérgicas após a ingestão de carne de porco contendo albumina sérica Sus s 1. Devido à homologia com outras albuminas séricas de mamíferos, reações com outras carnes também podem ocorrer. Reportamos um caso clínico bem documentado de uma doente com síndrome do gato-porco, com sintomas clínicos ligeiros e inespecíficos com ingestão de carne de porco cozinhada, que foram desvalorizados. O diagnóstico por componentes moleculares foi fundamental para estabelecer o diagnóstico, confirmando o envolvimento do Fed 2 e do Sus s 1, mas foi, no entanto, menos relevante na definição de dietas e evicção, uma vez que o perfil de sensibilização não se mostrou concordante com as manifestações clínicas.Ordem dos Médicos2022-05-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483Acta Médica Portuguesa; Vol. 35 No. 5 (2022): May; 388-391Acta Médica Portuguesa; Vol. 35 N.º 5 (2022): Maio; 388-3911646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483/6609Direitos de Autor (c) 2022 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessBarradas Lopes, JoanaLabrador-Horrilo, MoisesBartolomé, BorjaCunha, Leonor2023-05-14T03:00:34Zoai:ojs.www.actamedicaportuguesa.com:article/15483Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:39.134046Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report O Papel dos Alergénios Moleculares no Diagnóstico de Síndrome Gato-Porco: A Propósito de um Caso Clínico Raro |
title |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
spellingShingle |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report Barradas Lopes, Joana Cats/immunology Food Hypersensitivity/immunology Meat/adverse effects Serum Albumin/immunology Swine/immunology Albumina Sérica/imunologia Carne/efeitos adversos Gato/imunologia Hipersensibilidade Alimentar/imunologia Suíno/imunologia |
title_short |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
title_full |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
title_fullStr |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
title_full_unstemmed |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
title_sort |
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report |
author |
Barradas Lopes, Joana |
author_facet |
Barradas Lopes, Joana Labrador-Horrilo, Moises Bartolomé, Borja Cunha, Leonor |
author_role |
author |
author2 |
Labrador-Horrilo, Moises Bartolomé, Borja Cunha, Leonor |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Barradas Lopes, Joana Labrador-Horrilo, Moises Bartolomé, Borja Cunha, Leonor |
dc.subject.por.fl_str_mv |
Cats/immunology Food Hypersensitivity/immunology Meat/adverse effects Serum Albumin/immunology Swine/immunology Albumina Sérica/imunologia Carne/efeitos adversos Gato/imunologia Hipersensibilidade Alimentar/imunologia Suíno/imunologia |
topic |
Cats/immunology Food Hypersensitivity/immunology Meat/adverse effects Serum Albumin/immunology Swine/immunology Albumina Sérica/imunologia Carne/efeitos adversos Gato/imunologia Hipersensibilidade Alimentar/imunologia Suíno/imunologia |
description |
Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483/6609 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2022 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2022 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 35 No. 5 (2022): May; 388-391 Acta Médica Portuguesa; Vol. 35 N.º 5 (2022): Maio; 388-391 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130654986731520 |