The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report

• Autor(a) principal: Barradas Lopes, Joana
• Data de Publicação: 2022
• Outros Autores: Labrador-Horrilo, Moises, Bartolomé, Borja, Cunha, Leonor
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15483
• topic: Cats/immunology; Food Hypersensitivity/immunology; Meat/adverse effects; Serum Albumin/immunology; Swine/immunology; Albumina Sérica/imunologia; Carne/efeitos adversos; Gato/imunologia; Hipersensibilidade Alimentar/imunologia; Suíno/imunologia

Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.