Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/25445 |
Resumo: | Methicillin-resistant S. aureus (MRSA) are a threat to public health as they frequently reveal a multidrug-resistant pattern. Researchers all over the world are on an urgent hunt for new treatments to help fight infections before antibiotics become obsolete, and some natural alternatives, such as polyphenols, have already exhibited therapeutic properties. Therefore, this study aimed to determine the phenolic profile, antioxidant capacity, and antimicrobial activity against MRSA of the leaf, fruit, and stem bark extracts of Platanus hybrida. The polyphenols were extracted with a water/ethanol (20:80) mixture and the methodology included HPLC-DAD, DPPH, FRAP, and CuPRAC. To address this issue from a One Health perspective, the Kirby–Bauer disc diffusion method was performed against nine MRSA strains from three different sources (livestock, wild animals, and humans). Fourteen phenolics were identified and the leaf extract showed the highest phenolic content, followed by the fruit extract. The leaf extract also showed the highest antioxidant capacity while the fruit extract had the lowest antioxidant capacity. Both leaf and fruit extracts inhibited the growth of strains from all sources, while the stem bark extract did not inhibit the growth of human strains. This work highlights the complex chemical composition and the antioxidative and antimicrobial potential of extracts derived from P. hydrida. |
id |
RCAP_9bfb81f40cc6b25395e64b56c1398509 |
---|---|
oai_identifier_str |
oai:bibliotecadigital.ipb.pt:10198/25445 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA)Antimicrobial activityAntioxidant activityDrug-resistant bacteriaMRSAOne healthPhenolic compoundsMethicillin-resistant S. aureus (MRSA) are a threat to public health as they frequently reveal a multidrug-resistant pattern. Researchers all over the world are on an urgent hunt for new treatments to help fight infections before antibiotics become obsolete, and some natural alternatives, such as polyphenols, have already exhibited therapeutic properties. Therefore, this study aimed to determine the phenolic profile, antioxidant capacity, and antimicrobial activity against MRSA of the leaf, fruit, and stem bark extracts of Platanus hybrida. The polyphenols were extracted with a water/ethanol (20:80) mixture and the methodology included HPLC-DAD, DPPH, FRAP, and CuPRAC. To address this issue from a One Health perspective, the Kirby–Bauer disc diffusion method was performed against nine MRSA strains from three different sources (livestock, wild animals, and humans). Fourteen phenolics were identified and the leaf extract showed the highest phenolic content, followed by the fruit extract. The leaf extract also showed the highest antioxidant capacity while the fruit extract had the lowest antioxidant capacity. Both leaf and fruit extracts inhibited the growth of strains from all sources, while the stem bark extract did not inhibit the growth of human strains. This work highlights the complex chemical composition and the antioxidative and antimicrobial potential of extracts derived from P. hydrida.This work was supported by the projects UIDB/CVT/00772/2020 and LA/P/0059/2020 funded by the Portuguese Foundation for Science and Technology (FCT). This work was also supported by the Associate Laboratory for Green Chemistry-LAQV, which is financed by national funds from FCT/MCTES (UIDB/50006/2020 and UIDP/50006/2020) funded by FCT. The authors acknowledge the financial support of FCT by national funds under the project UIDB/04033/2020. Vanessa Silva is grateful to FCT for financial support through PhD grant SFRH/BD/137947/2018. To FCT, Portugal for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020) and the contract of L. Barros through the institutional scientific employment program-contract. This work was supported.Biblioteca Digital do IPBRibeiro, JessicaSilva, VanessaAires, AlfredoCarvalho, Rosa PaulaBarros, LillianGaivão, IsabelIgrejas, GilbertoPoeta, Patrícia2022-05-13T10:31:15Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/25445engRibeiro, Jessica; Silva, Vanessa; Aires, Alfredo; Carvalho, Rosa; Barros, Lillian; Gaivão, Isabel; Igrejas, Gilberto; Poeta, Patrícia (2022). Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA). Horticulturae. eISSN 2311-7524. 8:3, p. 1-1410.3390/horticulturae80302432311-7524info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:56:56Zoai:bibliotecadigital.ipb.pt:10198/25445Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:16:05.520481Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
title |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
spellingShingle |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) Ribeiro, Jessica Antimicrobial activity Antioxidant activity Drug-resistant bacteria MRSA One health Phenolic compounds |
title_short |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
title_full |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
title_fullStr |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
title_full_unstemmed |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
title_sort |
Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA) |
author |
Ribeiro, Jessica |
author_facet |
Ribeiro, Jessica Silva, Vanessa Aires, Alfredo Carvalho, Rosa Paula Barros, Lillian Gaivão, Isabel Igrejas, Gilberto Poeta, Patrícia |
author_role |
author |
author2 |
Silva, Vanessa Aires, Alfredo Carvalho, Rosa Paula Barros, Lillian Gaivão, Isabel Igrejas, Gilberto Poeta, Patrícia |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Ribeiro, Jessica Silva, Vanessa Aires, Alfredo Carvalho, Rosa Paula Barros, Lillian Gaivão, Isabel Igrejas, Gilberto Poeta, Patrícia |
dc.subject.por.fl_str_mv |
Antimicrobial activity Antioxidant activity Drug-resistant bacteria MRSA One health Phenolic compounds |
topic |
Antimicrobial activity Antioxidant activity Drug-resistant bacteria MRSA One health Phenolic compounds |
description |
Methicillin-resistant S. aureus (MRSA) are a threat to public health as they frequently reveal a multidrug-resistant pattern. Researchers all over the world are on an urgent hunt for new treatments to help fight infections before antibiotics become obsolete, and some natural alternatives, such as polyphenols, have already exhibited therapeutic properties. Therefore, this study aimed to determine the phenolic profile, antioxidant capacity, and antimicrobial activity against MRSA of the leaf, fruit, and stem bark extracts of Platanus hybrida. The polyphenols were extracted with a water/ethanol (20:80) mixture and the methodology included HPLC-DAD, DPPH, FRAP, and CuPRAC. To address this issue from a One Health perspective, the Kirby–Bauer disc diffusion method was performed against nine MRSA strains from three different sources (livestock, wild animals, and humans). Fourteen phenolics were identified and the leaf extract showed the highest phenolic content, followed by the fruit extract. The leaf extract also showed the highest antioxidant capacity while the fruit extract had the lowest antioxidant capacity. Both leaf and fruit extracts inhibited the growth of strains from all sources, while the stem bark extract did not inhibit the growth of human strains. This work highlights the complex chemical composition and the antioxidative and antimicrobial potential of extracts derived from P. hydrida. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-13T10:31:15Z 2022 2022-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/25445 |
url |
http://hdl.handle.net/10198/25445 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ribeiro, Jessica; Silva, Vanessa; Aires, Alfredo; Carvalho, Rosa; Barros, Lillian; Gaivão, Isabel; Igrejas, Gilberto; Poeta, Patrícia (2022). Platanus hybrida’s phenolic profile, antioxidant power, and antibacterial activity against methicillin-resistant staphylococcus aureus (MRSA). Horticulturae. eISSN 2311-7524. 8:3, p. 1-14 10.3390/horticulturae8030243 2311-7524 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799135444918599680 |