The apicomplexan parasite Toxoplasma gondii

Detalhes bibliográficos
Autor(a) principal: Delgado, Inês
Data de Publicação: 2022
Outros Autores: Zúquete, Sara, Santos, Dulce, Basto, Afonso Silva Pinto, Leitão, José Alexandre da Costa Perdigão e Cameira, Nolasco, Sofia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10437/12409
Resumo: Toxoplasma gondii is a ubiquitous zoonotic parasite with an obligatory intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for host cell invasion. When infecting its felid definitive host, T. gondii undergoes sexual reproduction in the intestinal epithelium, producing oocysts that are excreted with the feces and sporulate in the environment. In other hosts and/or tissues, T. gondii multiplies by asexual reproduction. Rapidly dividing tachyzoites expand through multiple tissues, particularly nervous and muscular tissues, and eventually convert to slowly dividing bradyzoites which produce tissue cysts, structures that evade the immune system and remain infective within the host. Infection normally occurs through ingestion of sporulated oocysts or tissue cysts. While T. gondii is able to infect virtually all warm-blooded animals, most infections in humans are asymptomatic, with clinical disease occurring most often in immunocompromised hosts or fetuses carried by seronegative mothers that are infected during pregnancy.
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spelling The apicomplexan parasite Toxoplasma gondiiBIOLOGIATOXOPLASMA GONDIITOXOPLASMOSEPARASITASCICLO DE VIDAAPICOMPLEXABIOLOGYTOXOPLASMA GONDIITOXOPLASMOSISPARASITESLIFE CYCLEAPICOMPLEXAToxoplasma gondii is a ubiquitous zoonotic parasite with an obligatory intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for host cell invasion. When infecting its felid definitive host, T. gondii undergoes sexual reproduction in the intestinal epithelium, producing oocysts that are excreted with the feces and sporulate in the environment. In other hosts and/or tissues, T. gondii multiplies by asexual reproduction. Rapidly dividing tachyzoites expand through multiple tissues, particularly nervous and muscular tissues, and eventually convert to slowly dividing bradyzoites which produce tissue cysts, structures that evade the immune system and remain infective within the host. Infection normally occurs through ingestion of sporulated oocysts or tissue cysts. While T. gondii is able to infect virtually all warm-blooded animals, most infections in humans are asymptomatic, with clinical disease occurring most often in immunocompromised hosts or fetuses carried by seronegative mothers that are infected during pregnancy.MDPI2022-01-18T15:15:19Z2022-01-01T00:00:00Z2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10437/12409enghttps://doi.org/10.3390/encyclopedia2010012Delgado, InêsZúquete, SaraSantos, DulceBasto, Afonso Silva PintoLeitão, José Alexandre da Costa Perdigão e CameiraNolasco, Sofiainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-09T14:06:07Zoai:recil.ensinolusofona.pt:10437/12409Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:13:44.694539Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The apicomplexan parasite Toxoplasma gondii
title The apicomplexan parasite Toxoplasma gondii
spellingShingle The apicomplexan parasite Toxoplasma gondii
Delgado, Inês
BIOLOGIA
TOXOPLASMA GONDII
TOXOPLASMOSE
PARASITAS
CICLO DE VIDA
APICOMPLEXA
BIOLOGY
TOXOPLASMA GONDII
TOXOPLASMOSIS
PARASITES
LIFE CYCLE
APICOMPLEXA
title_short The apicomplexan parasite Toxoplasma gondii
title_full The apicomplexan parasite Toxoplasma gondii
title_fullStr The apicomplexan parasite Toxoplasma gondii
title_full_unstemmed The apicomplexan parasite Toxoplasma gondii
title_sort The apicomplexan parasite Toxoplasma gondii
author Delgado, Inês
author_facet Delgado, Inês
Zúquete, Sara
Santos, Dulce
Basto, Afonso Silva Pinto
Leitão, José Alexandre da Costa Perdigão e Cameira
Nolasco, Sofia
author_role author
author2 Zúquete, Sara
Santos, Dulce
Basto, Afonso Silva Pinto
Leitão, José Alexandre da Costa Perdigão e Cameira
Nolasco, Sofia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Delgado, Inês
Zúquete, Sara
Santos, Dulce
Basto, Afonso Silva Pinto
Leitão, José Alexandre da Costa Perdigão e Cameira
Nolasco, Sofia
dc.subject.por.fl_str_mv BIOLOGIA
TOXOPLASMA GONDII
TOXOPLASMOSE
PARASITAS
CICLO DE VIDA
APICOMPLEXA
BIOLOGY
TOXOPLASMA GONDII
TOXOPLASMOSIS
PARASITES
LIFE CYCLE
APICOMPLEXA
topic BIOLOGIA
TOXOPLASMA GONDII
TOXOPLASMOSE
PARASITAS
CICLO DE VIDA
APICOMPLEXA
BIOLOGY
TOXOPLASMA GONDII
TOXOPLASMOSIS
PARASITES
LIFE CYCLE
APICOMPLEXA
description Toxoplasma gondii is a ubiquitous zoonotic parasite with an obligatory intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for host cell invasion. When infecting its felid definitive host, T. gondii undergoes sexual reproduction in the intestinal epithelium, producing oocysts that are excreted with the feces and sporulate in the environment. In other hosts and/or tissues, T. gondii multiplies by asexual reproduction. Rapidly dividing tachyzoites expand through multiple tissues, particularly nervous and muscular tissues, and eventually convert to slowly dividing bradyzoites which produce tissue cysts, structures that evade the immune system and remain infective within the host. Infection normally occurs through ingestion of sporulated oocysts or tissue cysts. While T. gondii is able to infect virtually all warm-blooded animals, most infections in humans are asymptomatic, with clinical disease occurring most often in immunocompromised hosts or fetuses carried by seronegative mothers that are infected during pregnancy.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-18T15:15:19Z
2022-01-01T00:00:00Z
2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10437/12409
url http://hdl.handle.net/10437/12409
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://doi.org/10.3390/encyclopedia2010012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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